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Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and preparation method thereof

A technology of Shuanghuanglian oral liquid and laryngotracheitis, which is applied to medical preparations containing non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc., which can solve the problem of loss of active ingredients, ineffective therapeutic effects, and onset of efficacy Slow and slow problems, to achieve the effect of increasing immune enhancement, excellent therapeutic effect, and long acting time

Pending Publication Date: 2018-11-30
广州白云山宝神动物保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] With the continuous development of my country's livestock and poultry breeding industry, the veterinary Shuanghuanglian preparation prepared with the existing Shuanghuanglian prescription has not very obvious preventive effect on livestock and poultry viral diseases, and the therapeutic effect is not significant, and it has not been fully developed. Playing the best pharmacological effect of Shuanghuanglian's classic antiviral prescription
On the one hand, the reason is that the preparation method of traditional Shuanghuanglian preparations is generally a water-alcohol method, and the preparation process is affected by decoction, filtration, concentration and other processes, resulting in the main active ingredients such as chlorogenic acid, forsythin, and baicalin. loss, effective biologically active substances degrade and fail, and their extraction rate is low; on the other hand, the extracted components of traditional Chinese medicine are complex, and it is inevitable that other components will affect the main components. There are few targeted antiviral components and lack of auxiliary body absorption. The auxiliary substances of the drug ingredients lead to the shortcomings of the traditional Shuanghuanglian preparations, such as slow onset of action and insignificant therapeutic effect after entering the body

Method used

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  • Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and preparation method thereof
  • Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and preparation method thereof
  • Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and preparation method thereof

Examples

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Effect test

Embodiment 1

[0052] This embodiment discloses Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis. The parts by weight of the raw materials are as follows:

[0053] 187.5 parts of honeysuckle, 187.5 parts of Scutellaria baicalensis, 750 parts of forsythia, 187.5 parts of Polygonum daqingye, 187.5 parts of Shegan, 0.50 parts of sodium selenite, and 50 parts of vitamin E.

[0054] In order to further improve the therapeutic effect of the Shuanghuanglian oral liquid, a sodium humate solution with a mass fraction of 50% is also used as a solvent.

[0055] In order to have stable properties and stable storage of the Shuanghuanglian oral liquid, it also contains 20 parts of a dispersant, 5 parts of an emulsifying wetting agent, 0.75 parts of an anti-mold preservative, 0.02 parts of an antioxidant, and 0.05 parts of an antifreezing and defoaming agent.

[0056] Wherein, the dispersant is sodium lignosulfonate;

[0057] The emulsifying wetting agent is at least on...

Embodiment 2

[0068] This embodiment discloses Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis, comprising the following raw materials in parts by weight:

[0069] 100 parts of honeysuckle, 100 parts of Scutellaria baicalensis, 500g of forsythia, 100 parts of Polygonum daqingye, 100 parts of Shegan, 0.1 parts of sodium selenite, 10 parts of vitamin E, 20 parts of sodium lignosulfonate, 5 parts of polysorbate-80, 0.5 parts of benzoic acid, 0.25 parts of methylparaben, 0.02 parts of butylated hydroxyanisole, and 0.05 parts of glycerin.

[0070] Its preparation method is with embodiment 1.

Embodiment 3

[0072] This embodiment discloses Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis, comprising the following raw materials in parts by weight:

[0073] 400 parts of honeysuckle, 400 parts of Scutellaria baicalensis, 1000g of forsythia, 200 parts of Polygonum daqingye, 200 parts of Shegan, 1 part of sodium selenite, 100 parts of vitamin E, 20 parts of sodium lignosulfonate, 5 parts of sucrose fatty acid ester, benzene 0.5 parts of sodium formate, 0.25 parts of ethyl paraben, 0.02 parts of dibutyl hydroxytoluene, and 0.05 parts of propylene glycol.

[0074] Its preparation method is with embodiment 1.

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Abstract

The invention discloses a Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and belongs to the technical field of poultry medicine. The Shuanghuanglian oral liquid is prepared from 100-400 parts by weight of honeysuckle, 100-400 parts by weight of radix scutellariae, 500-1000g of fructus forsythiae, 100-200 parts by weight of folium polygoni tinctorii, 100-200 parts by weight of blackberry lily, 0.1-1 part by weight of sodium selenite and 10-100 parts by weight of vitamin E. A preparation method of the Shuanghuanglian oral liquid utilizes sodium humate as a solvent and an ultra-high pressure crushing technology. The Shuanghuanglian oral liquid can be used for preventing and treating viral diseases such as infectious laryngotracheitis in poultry, replacesthe anti-viral chemical medicine, has remarkable curative effects and fully produces the best pharmacological effects of the classic Shuanghuanglian prescription.

Description

technical field [0001] The invention relates to the technical field of poultry medicine, in particular to a Shuanghuanglian oral liquid for preventing and treating infectious laryngotracheitis and a preparation method thereof. Background technique [0002] Infectious laryngotracheitis is an acute and highly contagious respiratory infectious disease of poultry caused by herpes virus, and is one of the most common viral diseases in poultry farming. Viral diseases have always been the most harmful and difficult to control diseases in the aquaculture industry, especially the poultry industry, which has seriously affected the development of my country's aquaculture industry. Such as: chicken viral diseases are widely prevalent in the world, which has caused serious economic losses to the chicken industry, and is one of the most serious diseases that endanger the poultry industry today. What is especially serious is that the avian influenza virus that has occurred many times in r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/00A61P11/00A61P31/22A61K31/355A61K33/04
CPCA61K9/0095A61K31/355A61K33/04A61K36/355A61K36/539A61K36/634A61K36/704A61K36/88A61K47/26A61P11/00A61P31/22A61K2300/00
Inventor 廖海标李城丰
Owner 广州白云山宝神动物保健品有限公司
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