Summer-heat removal agent for preventing and treating Newcastle disease and preparation method thereof

A technology for Newcastle disease and mixture, which is applied to medical preparations containing active ingredients, antiviral agents, pharmaceutical formulations, etc., can solve the problems of insignificant treatment effect, degradation of effective bioactive substances and ineffective treatment effect, etc.

Pending Publication Date: 2018-11-30
广州白云山宝神动物保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] With the continuous development of my country's livestock and poultry breeding industry, the preventive effect of Qingjie mixture for livestock and poultry viral diseases is not very obvious with the Qingjie mixture prepared from the existing Qingjie mixture prescription, and the therapeutic effect is not significant. Give full play to the best antiviral pharmacological effect of Qingjie Mixture Classical Prescription
On the one hand, the reason is that the preparation method of the traditional Qingjie mixture is generally the water-alcohol method, which is affected by decoction, filtration, concentration and other processes during the preparation process, resulting in the loss of the main effective drug components, and the degradation of effective biologically active components. On the other hand, the extracted components of traditional Chinese medicine are complex, and it is inevitable that other components will affect the main components. Its targeted antiviral components are less, and there is a lack of auxiliary substances to assist the body to absorb drug components. After the body, there are defects such as slow onset and unobvious therapeutic effect

Method used

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  • Summer-heat removal agent for preventing and treating Newcastle disease and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0060] This embodiment discloses a Qingjie mixture for preventing and treating Newcastle disease. The parts by weight of the raw materials are as follows:

[0061] 670 parts of gypsum, 140 parts of honeysuckle, 100 parts of scrophulariaceae, 80 parts of skullcap, 80 parts of rehmannia, 70 parts of forsythia, 70 parts of gardenia, 60 parts of gentian, 60 parts of sweet diding, 60 parts of isatid root, 60 parts of Anemarrhena 60 parts of Ophiopogon japonicus, 60 parts of Liaogewang, 45 parts of dark plum, 0.50 parts of sodium selenite, 50 parts of vitamin E, 5 parts of sucrose fatty acid ester, 0.5 parts of sodium benzoate, 0.25 parts of ethyl paraben, sodium ascorbate 0.02 parts, 0.05 parts of organic silicone.

[0062] In order to keep the properties of the Qingjie mixture for preventing and treating Newcastle disease stable and stable, it also contains 5 parts of emulsifying wetting agent, 0.75 part of anti-mold preservative, 0.02 part of antioxidant, and 0.05 part of antifre...

Embodiment 2

[0077] This embodiment discloses the Qingjie mixture for preventing and treating Newcastle disease, including the following raw materials in parts by weight:

[0078] 500 parts of gypsum, 100 parts of honeysuckle, 50 parts of Scrophulariaceae, 50 parts of Scutellaria baicalensis, 50 parts of rehmannia root, 50 parts of forsythia, 50 parts of gardenia, 30 parts of gentian, 30 parts of sweet diding, 30 parts of isatid root, 30 parts of Anemarrhena 30 parts of Ophiopogon japonicus, 10 parts of Liaogewang, 10 parts of dark plum, 0.1 part of sodium selenite, 10 parts of vitamin E, 5 parts of sucrose fatty acid ester, 0.5 part of sodium benzoate, 0.25 part of ethyl paraben, sodium ascorbate 0.02 parts, 0.05 parts of organic silicone. Its preparation method is with embodiment 1.

Embodiment 3

[0080] This embodiment discloses the Qingjie mixture for preventing and treating Newcastle disease, including the following raw materials in parts by weight:

[0081] 1000 parts of gypsum, 200 parts of honeysuckle, 150 parts of Scrophulariaceae, 150 parts of Scutellaria baicalensis, 150 parts of rehmannia root, 150 parts of forsythia, 150 parts of gardenia, 100 parts of gentian, 100 parts of candidia, 100 parts of isatidis, 100 parts of anemarrhena 100 parts of Ophiopogon japonicus, 150 parts of Liaogewang, 150 parts of dark plum, 1 part of sodium selenite, 100 parts of vitamin E, 5 parts of sucrose fatty acid ester, 0.5 part of sodium benzoate, 0.25 part of ethyl hydroxybenzoate, 0.02 part of dibutyl hydroxytoluene, 0.05 part of propylene glycol. Its preparation method is with embodiment 1.

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Abstract

The invention discloses a summer-heat removal agent for preventing and treating Newcastle disease and belongs to the technical field of poultry medicine. The summer-heat removal agent is prepared from500-1000 parts by weight of gypsum, 100-200 parts by weight of honeysuckle, 50-150 parts by weight of radix scrophulariae, 50-150 parts by weight of radix scutellariae, 50-150 parts by weight of unprocessed rehmannia root, 50-150 parts by weight of fructus forsythiae, 50-150 parts by weight of fructus gardenia, 30-100 parts by weight of radix gentianae, 30-100 parts by weight of manyflower gueldenstaedtid herb, 30-100 parts by weight of isatis root, 30-100 parts by weight of rhizoma anemarrhenae, 30-100 parts by weight of radix ophiopogonis, 10-150 parts by weight of root of indian stringbush, 10-150 parts by weight of dark plum, 0.1-1 part by weight of sodium selenite and 10-100 parts by weight of vitamin E. A preparation method utilizes an ultra-high pressure crushing technology. The summer-heat removal agent is suitable for veterinary clinical application and large-scale aquaculture industry development, replaces the antiviral chemical drug for preventing and treating viral diseases of livestock and poultry and fully produces the best antiviral pharmacological effects of the classic prescription.

Description

technical field [0001] The invention relates to the technical field of poultry medicine, in particular to a Qingjie mixture for preventing and treating Newcastle disease and a preparation method thereof. Background technique [0002] Newcastle disease (ND) is an acute, febrile, septic and highly contagious infectious disease of poultry caused by Newcastle disease virus. It is characterized by high fever, dyspnea, diarrhea, nervous disturbance, and mucosal and serosal hemorrhage. It has a high morbidity and fatality rate and is a major infectious disease that endangers the poultry industry. [0003] The traditional Qingjie mixture is a compound prescription composed of gypsum, honeysuckle, scrophulariaceae and other traditional Chinese medicines. Qingjie Mixture has the function of clearing heat and detoxifying, and can be used clinically to prevent and treat colds, fever, cough, sore throat and other diseases caused by viral infections. Chlorogenic acid and baicalin are t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P31/14A61K31/355A61K33/04A61K33/06
CPCA61K31/355A61K33/04A61K33/06A61K36/195A61K36/315A61K36/355A61K36/485A61K36/515A61K36/539A61K36/634A61K36/736A61K36/744A61K36/804A61K36/808A61K36/83A61K36/8964A61K36/8968A61P31/14A61K2300/00
Inventor 廖海标李城丰
Owner 广州白云山宝神动物保健品有限公司
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