A Blumea balsamifera tablet, and a preparation method thereof

A technology of Ainaxiang tablets and weighing scales, which is applied in the direction of pharmaceutical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve the problem of small drug loading per unit preparation, large amount of raw materials, and unstable preparations and other problems, to achieve the effect of improving bioavailability, simple preparation method, and short method process

Inactive Publication Date: 2019-01-15
贵州省罗甸县全兴药业开发有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current preparations using cinnamon cinnamon as raw materials have a large amount of raw materials, a small drug loading per unit preparation, and most of the methods are relatively complicated, and the preparations are unstable.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A kind of Ai Naxiang tablet, by weight 20-40 parts of microcrystalline fiber, 3-5 parts of mannitol, 2-4 parts of titanium dioxide, 1-3 parts of carboxymethyl starch sodium, 2-2 parts of colloidal silicon dioxide 4 parts and 0.8-1 part of glyceryl distearate.

[0014] A kind of preparation method of Ai Naxiang tablet, it comprises the steps:

[0015] (1) Weigh silicified microcrystalline cellulose and mannitol, and mix them evenly to obtain product A;

[0016] (2) Mix titanium dioxide, sodium carboxymethyl starch, and colloidal silicon dioxide to obtain product B;

[0017] (3) Mix product A and product B, add glyceryl distearate, mix and press into tablets to obtain the obtained product.

Embodiment 2

[0019] A kind of Ai Naxiang tablet, by weight 20 parts of microcrystalline fiber, 3 parts of mannitol, 2 parts of titanium dioxide, 1 part of sodium carboxymethyl starch, 2 parts of colloidal silicon dioxide and 0.8 parts of glyceryl distearate portion composition.

[0020] A kind of preparation method of Ai Naxiang tablet, it comprises the steps:

[0021] (1) Weigh silicified microcrystalline cellulose and mannitol, and mix them evenly to obtain product A;

[0022] (2) Mix titanium dioxide, sodium carboxymethyl starch, and colloidal silicon dioxide to obtain product B;

[0023] (3) Mix product A and product B, add glyceryl distearate, mix and press into tablets to obtain the obtained product.

Embodiment 3

[0025] A kind of Ai Naxiang tablet, by weight 40 parts of microcrystalline fiber, 5 parts of mannitol, 4 parts of titanium dioxide, 3 parts of sodium carboxymethyl starch, 4 parts of colloidal silicon dioxide and 1 part of glyceryl distearate portion composition.

[0026] A kind of preparation method of Ai Naxiang tablet, it comprises the steps:

[0027] (1) Weigh silicified microcrystalline cellulose and mannitol, and mix them evenly to obtain product A;

[0028] (2) Mix titanium dioxide, sodium carboxymethyl starch, and colloidal silicon dioxide to obtain product B;

[0029] (3) Mix product A and product B, add glyceryl distearate, mix and press into tablets to obtain the obtained product.

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PUM

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Abstract

A Blumea balsamifera tablet is disclosed and is prepared from, by weight, 20-40 parts of microcrystalline fiber, 3-5 parts of mannitol, 2-4 parts of titanium dioxide, 1-3 parts of sodium carboxymethylstarch, 2-4 parts of colloidal silica and 0.8-1 part of glycerol distearate. The tablet can reduce the daily dosage of the patient under the same crude drug content through the proportion of the Blumea balsamifera. Silicified microcrystalline cellulose, mannitol, and other adjuvants are reasonably prepared to give full play to the synergistic effect of each component. The silicified microcrystalline cellulose in the tablet and the added disintegrating agent carboxymethyl starch sodium can rapidly disintegrate the tablet, greatly improving the dissolution and absorption of the active ingredient, and improving the bioavailability of the drug. The preparation method is simple, the process is short and the production is easy.

Description

technical field [0001] The invention relates to an Ainaxiang tablet and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Ainaxiang, also known as Baihua Jiuliming and Huaainaxiang, is derived from the dry whole herb of Asteraceae plant False Dongfeng. It is mainly produced in southwestern Guangxi and southeastern Yunnan. It is often grown in forest edges, hillside shrubs or dense forests. . Guiai Naxiang is a traditional Chinese herbal medicine commonly used by ethnic minorities in Southwest China. Zhuang doctors believe that it has a slightly bitter taste and mild warm nature. As a folk herbal medicine of the Zhuang nationality, Guiai Naxiang has a unique curative effect on clinically treating women's functional uterine bleeding, postpartum hemorrhage, early menstruation, postpartum metrorrhagia, postpartum edema, infertility, and vaginal sores. However, the current preparations using cinnamon cin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K47/38A61K47/36A61P15/00A61P7/04A61P15/08
CPCA61K36/28A61K9/2054A61K9/2059
Inventor 胡全贵
Owner 贵州省罗甸县全兴药业开发有限责任公司
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