Yunnan olive freeze-dried ultrafine powder buccal tablet, preparation method and application thereof

Abstract

The invention relates to a Yunnan olive freeze-dried ultrafine powder buccal tablet, a preparation method and application thereof, and belongs to the field of traditional Chinese medicine preparation.The freeze-dried ultrafine powder buccal tablets of Yunnan olive obtained by ultrafine pulverization technology have good dispersibility and solubility, which is favorable for drug release and absorption, can improve bioavailability, is favorable for molding, and is widely used. The freeze-dried ultrafine powder buccal tablets of Yunnan olive can reduce the transformation of macrophages into lipid-rich foam cells.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to the use of a Yunnan olive preparation for preparing anti-atherosclerosis drugs, in particular to the use of a Yunnan olive freeze-dried ultrafine powder preparation for preparing a drug for reducing lipid content in foam cells . Background technique [0002] Yunnan olive, also known as Yunnan olive, Niugao, throat Ganzi, Yanggan, Huiganzi, oil glycerin, grapefruit Gan, emblica, etc., is a species of Yunnan olive (Phyllanthus emblica L.) The fruit is an important medicinal and edible plant resource. It has a very long history in traditional Chinese medicine systems such as Chinese herbal medicine and ethnic medicine. About 16 ethnic groups use this medicine. Yunnan olive has the effects of clearing away heat and cooling blood, promoting digestion and invigorating the stomach, promoting body fluid and quenching thirst. It is traditionally used to treat blood heat and bloo...

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Problems solved by technology

In my country, it is mainly distributed in 8 provinces including Yunnan, Guangxi, Guangdong, Fujian, Hainan, Taiwan, Sichuan and Guizhou, among which Yunnan and Fujian are the most distributed, and Yunnan olives are concentrated in Jinsha River, Nanpan River, Yuan River, Lancang River and Nu River and other five major water system areas, according to survey statistics, Yunnan Province currently has 600,000 to 700,000 mu of Yunnan olive groves, with an area suitable for growth of more than 3 million mu, with an annual output of about 10,000 tons of fresh fruit, but the utilization rate is less than 10%. One of the few natural resources that can be developed sustainably and on a large scale

[0009] Yunnan olives are rich in nutrition and have a unique taste. Currently, the production of Yunnan olive products on the market mostly adopts the method of squeezing the juice of Yunnan olive fruit, drying and concentrating after squeezing the juice, and solvent extraction. These methods only use the fruit juice components of Yunnan olive fruit. A large number of beneficial ingredients in the pulp are discarded. In addition, these methods will also destroy the beneficial effects of heat sensitivity or structural instability in Yunnan olives, resulting in the inability of the nutrients to be fully utilized.

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