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Antibacterial gynecological composition, and antibacterial gynecological gel and preparation method thereof

A composition and gynecological technology, applied in the field of gel and its preparation, antibacterial gynecological composition, can solve the problems of unsatisfactory effect of traditional Chinese medicine, need to improve efficacy, limited bactericidal effect, etc. effect, improving quality of life

Inactive Publication Date: 2019-02-01
湖北李时珍现代生物医药集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Medicines for external use are further divided into Chinese patent medicines, chemical medicines, and mixtures of Chinese and Western medicines; chemical medicines have obvious bactericidal effects and quick results, but they are highly targeted and have no effect on other complications caused by infection, and the recurrence rate is high; The effect is limited, and it is often necessary to use it together with other drugs to achieve the effect; however, the effect of the existing Chinese patent medicines is not satisfactory, and the efficacy needs to be improved

Method used

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  • Antibacterial gynecological composition, and antibacterial gynecological gel and preparation method thereof
  • Antibacterial gynecological composition, and antibacterial gynecological gel and preparation method thereof
  • Antibacterial gynecological composition, and antibacterial gynecological gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1. An antibacterial gynecological composition

[0027] The composition includes the following components in parts by weight: 2 parts of Artemisia argyi extract, 4 parts of Cnidium mongolica, 4 parts of Sophora flavescens, and 3 parts of safflower.

[0028] 2. An antibacterial gynecological gel

[0029] Composition: 2 parts of Artemisia argyi extract, 4 parts of Fructus Cnidii, 4 parts of Sophora flavescens, 3 parts of safflower;

[0030] Excipients: 0.3 parts of gel base (xanthan gum); 1 part of emulsifier (Tween 80); 1 part of humectant (glycerol);

[0031] 3. Preparation method of antibacterial gynecological gel

[0032] Follow the steps below:

[0033] (1) Fructus Cnidii, Sophorae flavescens and safflower are dried, adopt pulverizer to pulverize respectively, obtain the Chinese medicinal material powder, the powder diameter control is 60-80 order;

[0034] (2) Get Fructus Cnidii, Radix Sophora Radix and Fructus Cnidii Chinese medicinal material powder respectivel...

Embodiment 2

[0037] 1. An antibacterial gynecological composition

[0038] The composition comprises the following components in parts by weight: 5 parts of Artemisia argyi extract, 10 parts of Fructus Cnidii, 10 parts of Sophora flavescens, and 7 parts of safflower.

[0039] 2. An antibacterial gynecological gel

[0040] Composition: 5 parts of Artemisia argyi extract, 10 parts of Fructus Cnidii, 10 parts of Sophora flavescens, 7 parts of safflower;

[0041] Excipients: 1.5 parts of gel matrix (carbomer); 3 parts of emulsifier (Tween 80); 5 parts of humectant (sorbitol);

[0042] 3. Preparation method of antibacterial gynecological gel

[0043] Follow the steps below:

[0044] (1) Fructus Cnidii, Sophorae flavescens and safflower are dried, adopt pulverizer to pulverize respectively, obtain the Chinese medicinal material powder, the powder diameter control is 60-80 order;

[0045] (2) Get Fructus Cnidii, Radix Sophora Radix and Fructus Cnidii Chinese medicinal material powder respecti...

Embodiment 3

[0048]1. An antibacterial gynecological composition

[0049] The composition includes the following components in parts by weight: 3 parts of Artemisia argyi extract, 7 parts of Cnidium mongolica, 8 parts of Sophora flavescens, and 5 parts of safflower.

[0050] 2. An antibacterial gynecological gel

[0051] Composition: 3 parts of Artemisia argyi extract, 7 parts of Fructus Cnidii, 8 parts of Sophora flavescens, 5 parts of safflower;

[0052] Excipients: 1 part of gel base (xanthan gum); 2 parts of emulsifier (Tween 80); 2 parts of humectant (glycerol);

[0053] 3. Preparation method of antibacterial gynecological gel

[0054] Follow the steps below:

[0055] (1) Fructus Cnidii, Sophorae flavescens and safflower are dried, adopt pulverizer to pulverize respectively, obtain the Chinese medicinal material powder, the powder diameter control is 60-80 order;

[0056] (2) Get Fructus Cnidii, Radix Sophora Radix and Fructus Cnidii Chinese medicinal material powder respectively,...

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Abstract

The invention discloses an antibacterial gynecological composition, and an antibacterial gynecological gel and a preparation method thereof, wherein the antibacterial gynecological composition comprises, by weight, 2-5 parts of a Qichun Artemisia argyi extraction liquid, 4-10 parts of Fructus cnidii, 4-10 parts of Sophora flavescens Ait, and 3-7 parts of safflower. The antibacterial gynecologicalgel comprises auxiliary materials and the antibacterial gynecological composition, wherein the auxiliary materials comprise a gel matrix, an emulsifier, a humectant and an acidity adjuster. Accordingto the present invention, the antibacterial gynecological composition uses the Qichun Artemisia argyi extraction liquid as the principal drug so as to inhibit most of Gram-negative bacteria and Gram-positive bacteria and ensure the antibacterial property of the drug; the antibacterial gynecological composition uses Fructus cnidii and Sophora flavescens Ait as the ministerial drug so as to achievethe assisted treatment of gynecological inflammatory complications, improve the efficacy, accelerate the healing, effectively kill bacteria, stop itching, kill insects, maintain the vaginal acid-basebalance, and achieve effects of heat clearing, dampness removing, stagnation eliminating and swelling subsiding; and the antibacterial gynecological composition uses safflower as the adjunctive drug,wherein safflower has good treatment effects yin deficiency hemophthisis, dysmenorrhea, unsmooth menstrual discharge and other symptoms.

Description

technical field [0001] The invention relates to the technical field of gynecological medicines, in particular to an antibacterial gynecological composition, a gel and a preparation method thereof. Background technique [0002] Gynecological inflammation, including vaginitis, cervicitis, etc., is an inflammation caused by the invasion of pathogenic bacteria due to external injury or infection. For the current treatment of gynecological diseases, it is divided into internal medicine and external medicine. Internal medicine is mainly a kind of medicine, and the dosage forms include capsules, dripping pills, etc.; external medicine is mainly chemical drugs, and the dosage forms are mostly built-in suppositories and tablets. Excessive consumption of gynecological chemicals can easily destroy the relationship between the bacteria in the introduction tract, leading to adverse effects such as drug resistance. Suppositories and tablets are inconvenient to eat and can easily cause v...

Claims

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Application Information

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IPC IPC(8): A61K36/489A61K9/06A61P15/00A61P15/02A61P31/04
CPCA61K9/0034A61K9/06A61K36/234A61K36/282A61K36/286A61K36/489A61K47/26A61K47/36A61P15/00A61P15/02A61P31/04A61K2300/00
Inventor 刘子昂伊晓波胡军斌
Owner 湖北李时珍现代生物医药集团有限公司
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