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Application of bletilla striata(Thunb.)Rchb.f. extract

A technology of extract and bletilla striata, applied in the field of application of bletilla striata extract

Inactive Publication Date: 2019-03-22
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no report that Bletilla striata extract has the ability to increase the expression of basement membrane-related genes and anti-aging-related genes, stabilize skin structure, and is suitable for cosmetics with anti-aging effects

Method used

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  • Application of bletilla striata(Thunb.)Rchb.f. extract
  • Application of bletilla striata(Thunb.)Rchb.f. extract
  • Application of bletilla striata(Thunb.)Rchb.f. extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The production of embodiment 1 bletilla striata extract (1)

[0026] (1) Take the medicinal material of Bletilla striata, dry it until the water content is lower than 5%, take 100g after crushing, add 1.5L deionized water to decoct for 0.5-1h; centrifugally filter, and collect the filtrate;

[0027] (2) Add 1.5L of deionized water to the filter residue and decoct for 0.5h again, and combine the filtrate;

[0028] (3) Freeze-drying or spray-drying after concentration.

Embodiment 2

[0029] The production of embodiment 2 bletilla striata extract (2)

[0030] (1) Take the medicinal material of Bletilla striata, dry it until the water content is less than 5%, take 100g after crushing, first soak in 0.5L 70% ethanol for 12h or decoct for 5min, and take the filter residue; or soak it in 1L of acetone for 12h, take the filter residue to remove the acetone;

[0031] (2) according to the method for embodiment 1, add deionized water and decoct twice, combine filtrate;

[0032] (3) Freeze-drying or spray-drying after concentration.

Embodiment 4

[0033] The production of embodiment 4 bletilla striata extract (4)

[0034] In step (2) of Example 1 or 2, after combining the filtrates, concentrate to 500 mL, add 1.5-2 L of ethanol, and let stand for 6-24 hours; filter to collect the precipitate and dry it.

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Abstract

The invention relates to the field of daily chemicals and plant extracts, in particular to application of a bletilla striata(Thunb.)Rchb.f extract. The bletilla striata(Thunb.)Rchb.f extract has the ability of improving the expression of basilar membrane related genes and anti-aging related genes, and can effectively improve the expression of anti-aging effect related genes hbegf (heparin bindingEGF like growth factor), csf2 (colony stimulating factor 2) and egfr (epidermal growth factor receptor), and a basilar membrane stabilization related gene hspg2 (heparan sulfate proteoglycan) at the content of 0.01 percent. Thus, the bletilla striata(Thunb.)Rchb.f extract can be used for preparing external skin agents, and can serve as an anti-aging active component for firming a skin structure orstabilizing a dermal-epidermis junction.

Description

technical field [0001] The invention relates to the fields of daily chemicals and plant extracts, in particular to the application of the bletilla striata extract. Background technique [0002] The skin covers the entire human body and is in direct contact with the external environment. In addition to protecting the body from various external factors, the skin is also a mirror that reflects the health of the whole body. Skin is composed of epidermis, dermis, and subcutaneous tissue, and contains skin appendages, abundant nerves, blood vessels, lymphatic vessels, and muscles. The connecting area between the dermis and the epidermis is also called the basement membrane zone. It is not only a layer of structural model, but also has various functions. The basement membrane is the support pad of epithelial cells and plays a structural connection between epithelial cell tissue and connective tissue. , but also has other effects. For example, the basement membrane acts as a barri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61Q19/08A61Q19/00A61K36/898A61P17/18A61P17/00
CPCA61K36/898A61Q19/00A61Q19/08A61K8/97A61K9/0014
Inventor 史晓婷宋肖洁戴竞蒋耀权章漳吴越
Owner JALA GROUP CORPORATION
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