Bone-like Havers system bioactive scaffold and its preparation method and application
A bioactive, bone-like technology, used in bone implants, medical science, prostheses, etc., can solve the problems of uneven size of stent holes, inability to prepare bioceramic stents, low mechanical strength, etc., to promote osteogenesis and angiogenesis effect
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Embodiment 1
[0058] Use 3ds Max software to design the bracket model, the design size is 10mm in diameter, 3mm in height cylindrical bone imitation Havers system structure bracket, in which the diameter of Havers tube is divided into three types: 1.6mm, 1.2mm, 0.8mm, and the number of Havers tube is 8 indivual. Output the drawn bracket model as an STL format file and import it into the software that comes with the photocuring printer (purchased from Beijing Shiwei Technology Co., Ltd., model autocera-m) for slicing, generate a TDP format file and import it into the printer.
[0059] Pure feldspar powder (purchased from Kunshan Huaqiao Technology New Material Co., Ltd.) 60g, and 1.5g45S5 bioglass powder (purchased from Kunshan Huaqiao Technology New Material Co., Ltd.), 41g photosensitive resin (epoxy acrylic resin, purchased from Jinhua Wanhao Accessories Co., Ltd.) mixed ball mill to obtain the photosensitive ceramic slurry, and put the prepared slurry in the printer for printing to obtai...
Embodiment 2
[0062] Use 3ds Max software to design the bracket model, the design size is 10mm in diameter, 3mm in height cylindrical bone imitation Havers system structure bracket, in which the diameter of Havers tube is 1.6mm, the number of Havers tubes is divided into 2, 4, 8 three kind. Output the drawn bracket model as an STL format file and import it into the software that comes with the photo-curing printer for slicing processing, generate a TDP format file and import it into the printer.
[0063] 50g of pure feldspar powder, mixed with 1.25g of 45S5 bio-glass powder, and 51.25g of photosensitive resin are ball-milled to obtain a photosensitive ceramic slurry, and the prepared slurry is placed in a printer for printing to obtain a scaffold material.
[0064] The printed scaffold was calcined at 1350°C for 3 hours to obtain a pure feldspar ceramic scaffold.
Embodiment 3
[0066] Use 3ds Max software to design the bracket model, the design size is 10mm in diameter, 3mm in height cylindrical bone imitation Havers system structure bracket, in which the diameter of Havers tube is 1.6mm, the number of Havers tubes is divided into 2, 4, 8 three kind. Output the drawn bracket model as an STL format file and import it into the software that comes with the photo-curing printer for slicing processing, generate a TDP format file and import it into the printer.
[0067] 50g of pure β-TCP powder (purchased from Kunshan Huaqiao Technology New Material Co., Ltd.) was mixed with 50g of photosensitive resin and ball-milled to obtain a photosensitive ceramic slurry, and the prepared slurry was placed in a printer for printing to obtain a scaffold material.
[0068] The printed scaffolds were calcined at 1100 °C for 3 hours to obtain pure β-TCP ceramic scaffolds.
[0069] The obtained scaffolds were characterized and evaluated for bioactivity, osteogenesis and a...
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Abstract
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