A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, its preparation method and application

A technology of ceramide and composition, which is applied in the field of moisturizing, anti-inflammatory and anti-wrinkle compositions, can solve the problems of difficult application of water-based cosmetics, easy crystallization and precipitation, etc., and achieve the effect of not being easily affected by external factors, avoiding the phenomenon of Austenitic ripening, and excellent moisturizing Effect

Active Publication Date: 2021-11-05
广州科斯曼生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since ceramide is fat-soluble and easy to crystallize and precipitate, it is difficult to apply in water-based cosmetics, especially transparent water-based products (such as lotion, essence, etc.)

Method used

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  • A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, its preparation method and application
  • A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, its preparation method and application
  • A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] A moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide, the raw material composition of which is shown in the following table:

[0058] Table 1 A composition of raw materials of a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide

[0059]

[0060] The preparation method of the above-mentioned moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide comprises the following steps:

[0061] 1) Mix isomeric sugars, sodium stearyl glutamate, butanediol and water, heat to 85°C, and stir evenly to obtain a mixed solution;

[0062] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0063]3) Add the mixed solution of step 1) and the liquid mixture of step 2) into a homogenizer for homogenization (the speed of the homogenizer is 10000r / min), then cool...

Embodiment 2

[0078] A moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide, the raw material composition of which is shown in the following table:

[0079] Table 3 Raw material composition table of a moisturizing anti-inflammatory anti-wrinkle composition comprising ceramide

[0080]

[0081] The preparation method of the above-mentioned moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide comprises the following steps:

[0082] 1) Mix isomeric sugars, sodium stearyl glutamate, butanediol and water, heat to 85°C, and stir evenly to obtain a mixed solution;

[0083] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0084] 3) Add the mixed solution of step 1) and the liquid mixture of step 2) into a homogenizer for homogenization (the speed of the homogenizer is 10000r / min), then cool the...

Embodiment 3

[0098] A moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide, the raw material composition of which is shown in the following table:

[0099] Table 5 A raw material composition table of a moisturizing anti-inflammatory anti-wrinkle composition comprising ceramide

[0100]

[0101] The preparation method of the above-mentioned moisturizing, anti-inflammatory and anti-wrinkle composition comprising ceramide comprises the following steps:

[0102] 1) Mix isomeric sugars, sodium stearyl glutamate, butanediol and water, heat to 85°C, and stir evenly to obtain a mixed solution;

[0103] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0104] 3) Add the mixed solution of step 1) and the liquid mixture of step 2) into a homogenizer for homogenization (the speed of the homogenizer is 10000r / min), then cool t...

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PUM

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Abstract

The invention discloses a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and its preparation method and application. The composition is composed of isomerized sugar, phosphatidylcholine, ceramide, phytosterol, sodium stearyl glutamate, butanediol and water; the phosphatidylcholine and ceramide form a sphingomyelin-like structure. The preparation method comprises the following steps: 1) preparing a mixed solution of isomerized sugar, sodium stearyl glutamate and butanediol; 2) preparing a liquid mixture of phosphatidylcholine, ceramide and phytosterol; 3) step 1 ) of the mixed solution and step 2) of the liquid mixture of homogenization, micro-fluidic treatment and filtration. The composition of the present invention has excellent moisturizing, anti-inflammation and anti-wrinkle effects, and is easy to absorb through the membrane. When added to transparent water-based cosmetics, it has a transparent appearance, long-term stability, no delamination and turbidity, and its preparation process is simple and can be used on a large scale. Production.

Description

technical field [0001] The invention relates to a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, a preparation method and application thereof. Background technique [0002] The barrier function of the skin is mainly provided by the stratum corneum, the outermost layer of the skin. The stratum corneum has a structure similar to a brick wall. Keratinocytes (flat cells without nuclei) are "bricks" embedded in lipid "cement". It is mainly composed of ceramide, cholesterol and fatty acid. The proportion of ceramide in the horny sebum is 40%-50%, which can make the intercellular lipids in the stratum corneum form a multilayer lamination structure, and further form a high-viscosity two-way lipid layer to prevent or reduce transdermal The effect of water loss. The reduction of ceramide will directly affect the skin barrier function, resulting in increased skin water loss and easier invasion of external harmful substances, eventually causing dry a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/68A61K8/63A61K8/60A61K8/55A61K8/34A61K8/44A61P29/00A61Q19/00A61Q19/08
CPCA61K8/345A61K8/44A61K8/55A61K8/60A61K8/63A61K8/68A61K2800/413A61Q19/00A61Q19/08A61P29/00
Inventor 庄福平
Owner 广州科斯曼生物科技有限公司
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