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Medicament for treating hepatitis and preparation method thereof
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A technology for medicament and hepatitis, applied in the field of drug preparation, can solve the problems of complex preparation conditions, influence of drug quality, etc., and achieve the effects of simple preparation process, good therapeutic effect and fast absorption
Inactive Publication Date: 2019-08-16
南京博源医药科技有限公司
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Abstract
Description
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Problems solved by technology
[0005] Therefore, the preparation conditions of existing hepatitis drugs are complicated, and some organic solvents are often used in the drug preparation process. Although they will be removed by evaporation and distillation in the subsequent process, a small amount of residue will also affect the quality of the drug.
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preparation example Construction
[0042] A preparation method of a medicament for treating hepatitis, comprising the following steps:
[0043] (1) After mixing Capillaris and meglumine, add it to a ball mill to grind, sieve, add deionized water, heat up to 50~80°C, and stir to obtain mixture A;
[0044] (2) Add curcumin, Bupleurum and Scutellaria baicalensis to mixture A, and then perform ultrasonic treatment at 60-100°C to obtain mixture B;
[0045] (3) Grind and sievedandelion and betaine, add to mixture B, ultrasonically treat at 50-80°C for 30-60 minutes, freeze-dry in vacuum, add to granulator, and granulate to treat hepatitis medicine.
Embodiment 1
[0047] A medicament for treating hepatitis, comprising the following components in parts by weight: 60 parts of capillary, 8 parts of meglumine, 12 parts of curcumin, 50 parts of Bupleurum, 28 parts of Scutellaria baicalensis, and 32 parts of dandelion , Betaine is 3 parts.
[0048] A preparation method of a medicament for treating hepatitis, comprising the following steps:
[0049] (1) After mixing 60g capillary capillary and 8g meglumine, put into a ball mill and grind for 30 minutes, sieve through a 100-mesh filter, add 50g of deionized water, heat up to 50°C, and stir to prepare mixture A;
[0050] (2) Add 12g curcumin, 50g Bupleurum and 28g Scutellaria baicalensis to mixture A, and then ultrasonicate at 60°C, the ultrasonic treatment conditions are ultrasonic power 1000W, ultrasonic time 20min to obtain mixture B;
[0051] (3) Grind dandelion and betaine with a ball mill, sieve through a 150-mesh filter, add to mixture B, and ultrasonically treat at 50°C for 30 minutes. ...
Embodiment 2
[0053] A medicament for treating hepatitis, comprising the following components in parts by weight: 50 parts of capillary, 5 parts of meglumine, 10 parts of curcumin, 40 parts of Bupleurum, 25 parts of Scutellaria baicalensis, and 30 parts of dandelion , Betaine is 2 parts.
[0054] A preparation method of a medicament for treating hepatitis, comprising the following steps:
[0055] (1) After mixing 50g of capillary capillary and 5g of meglumine, put into a ball mill and grind for 30 minutes, sieve through a 150-mesh filter, add 40g of deionized water, heat up to 65°C, and stir to obtain mixture A;
[0056] (2) Add 10g curcumin, 40g Bupleurum and 25g Scutellaria baicalensis to mixture A, and then conduct ultrasonic treatment at 80°C. The ultrasonic treatment conditions are that the ultrasonic power is 1100W, and the ultrasonic time is 25min to obtain mixture B;
[0057] (3) Grind dandelion and betaine with a ball mill, sieve through a 200-mesh filter, add to mixture B, and ul...
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Abstract
The invention discloses a medicament for treating hepatitis and a preparation method thereof, wherein the medicament comprises the following components in parts by weight: 50-70 parts of oriental wormwood, 5-10 parts of meglumine, 10-15 parts of curcumin, 40-60 parts of radix bupleuri, 25-30 parts of scutellaria baicalensis, 30-35 parts of dandelion, and 2-5 parts of betaine. The preparation method of the medicament for treating hepatitis comprises the following steps: mixing oriental wormwood and meglumine, adding the mixture into a ball mill, grinding, sieving, adding deionized water, heating up to 50-80 DEG C, stirring, and preparing a mixture A; adding curcumin, radix bupleuri and scutellaria baicalensis into the mixture A, and then carrying out ultrasonic treatment at the temperatureof 60-100 DEG C, to obtain a mixture B; and grindingdandelion and betaine, sieving, then adding to the mixture B, carrying out ultrasonic treatment at the temperature of 50-80 DEG C for 30-60 min, after vacuum freeze-drying, adding to a granulator, and granulating to obtain the medicament for treating hepatitis. The invention provides the medicament for treating hepatitis and the preparation method thereof. Through three-step operation, the preparation process is simple, the preparation process does not need organic solvents and the pollution cannot be caused.
Description
technical field [0001] The invention relates to a medicament for treating hepatitis and a preparation method thereof, belonging to the technical field of medicine preparation. Background technique [0002] Hepatitis is a common infectious disease caused by a variety of hepatitis viruses. The main clinical manifestations are fatigue, loss of appetite, nausea, vomiting, hepatomegaly and liver function damage. Some patients may have jaundice and fever. Since hepatitis has the characteristics of strong infectivity, complex transmission route, wide prevalence and high incidence rate, the research and development of hepatitis drugs is one of the key points of drug research and development at this stage. [0003] At present, the medical treatment of hepatitis, especially the treatment of hepatitis B, etc., mainly adopts antiviral therapy. Patients receiving formal antiviral treatment are still relatively limited, so most patients can only prevent the further development of the dis...
Claims
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Application Information
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