Preparation method and application for glycosylated naringenin

A technology of naringenin and glycosylation, applied in the field of bioengineering, can solve problems such as low bioavailability of naringenin, complex extraction, separation process, research affecting pharmacological activity, etc., to achieve improved bioavailability and broad development Foreground, effect of solubility improvement
CN110205351APending Publication Date: 2019-09-06FOSHAN GOLDEN HEALTH TECH CO LTD

Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
FOSHAN GOLDEN HEALTH TECH CO LTD
Publication Date
2019-09-06

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Abstract

The present disclosure provides a preparation method for glycosylated naringenin, wherein the preparation method is characterized by particularly comprising the steps: putting raw materials and glycosyl donors into a reaction buffer solution, mixing the feed liquid evenly, and then adding glycosidase and glycosyltransferase into the reaction system, wherein the raw materials are naringin and naringenin extracts or conversion products and derivatives thereof. The glycosylated naringenin prepared by the method can have the solubility of naringenin greatly improved by adding 1-9 glycosyl groups to a flavone matrix, not only solves the problem of poor solubility of naringenin, but also solves the problem of decomposition and absorption of naringenin in a human body, and greatly improves the bioavailability of naringenin.
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Description

technical field

[0001] The disclosure relates to the field of bioengineering, in particular to a preparation method and application of glycosylated naringenin. Background technique

[0002] Citrus is one of the fruits with the largest planting area in my country. There are a large number of small, thin, and secondary citrus fruits every year. These fruits are generally just thrown away directly, causing a lot of waste of resources. Literature reports: the content of citrus hesperidin in the small fruit, fruit thinning and falling fruit of citrus is the highest in the whole growth cycle. Therefore, it is of high economic value to extract flavonoids from small fruit, fruit thinning and fruit drop produced during the growth of citrus.

[0003] Flavonoids are treasures given to humans by nature. At present, there are about 4,000 kinds of flavonoids, which mainly exist in leaves, fruits, roots, and bark of plants. They have similar mother nucleus structures, but the structure t...

Claims

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