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Traditional Chinese medicine composition for treating diabetic skin ulcer and preparation method thereof

A technology for skin ulcers and compositions, applied in the field of traditional Chinese medicine compositions, can solve problems such as unsatisfactory therapeutic effects, and achieve the effects of tissue growth and repair, good therapeutic effects, and improved blood circulation

Active Publication Date: 2019-09-10
北京市中医研究所
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many drugs for the treatment of diabetic skin ulcers, but the therapeutic effect is not ideal

Method used

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  • Traditional Chinese medicine composition for treating diabetic skin ulcer and preparation method thereof
  • Traditional Chinese medicine composition for treating diabetic skin ulcer and preparation method thereof

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] According to another aspect of the present invention, there is also provided a preparation method of a Chinese medicine composition for treating diabetic skin ulcer, comprising the following steps:

[0059] (a) raw Astragalus membranaceus, fried Atractylodes macrocephala, Atractylodes macrocephala, cinnamon, aconite, antler cream, papaya, white mustard seed, rehmannia glutinosa, angelica, northern ginseng, and optionally ghost arrow feathers and optionally Shouwu vine in the prescribed amount, add water performing multiple decoctions and separations, combining and concentrating the decoctions obtained through multiple separations to obtain a concentrate;

[0060] (b) carrying out alcohol precipitation and separation on the concentrated solution, concentrating and drying the separated alcohol precipitation supernatant to obtain a traditional Chinese medicine composition for treating diabetic skin ulcer.

[0061] The preparation method of the traditional Chinese medicine ...

Embodiment approach

[0076] As a preferred embodiment of the present invention, the preparation method of the traditional Chinese medicine composition for the treatment of diabetic skin ulcers comprises the following steps:

[0077] (a) raw Astragalus membranaceus, fried Atractylodes macrocephala, Atractylodes macrocephala, cinnamon, aconite, antler cream, papaya, white mustard seed, rehmannia glutinosa, angelica, northern ginseng, and optionally ghost arrow feathers and optionally Shouwu vine in the prescribed amount, add water Decocting and separating for many times, combining the decoctions obtained by multiple separations, and concentrating until each milliliter of medicinal liquid contains 0.8-1.2 g of crude drug to obtain a concentrated liquid;

[0078] (b) using 1.5 to 4 times the amount of ethanol with a volume fraction of 90 to 95% to carry out alcohol precipitation and separation on the concentrated solution, and to carry out decompression concentration of the separated alcohol precipitat...

Embodiment 1

[0086] This example provides a traditional Chinese medicine composition for treating diabetic skin ulcers, which is made of the following raw materials in parts by weight: 20 parts of raw Radix Astragali, 20 parts of fried Atractylodes Rhizoma Atractylodes Rhizome, 5 parts of Atractylodes Rhizome, 30 parts of Poria cocos, 6 parts of cinnamon, 5 parts of aconite, 5 parts of antler cream, 5 parts of papaya, 8 parts of white mustard seed, 12 parts of rehmannia glutinosa, 15 parts of angelica and 10 parts of northern ginseng.

[0087] The preparation method of the Chinese medicine composition for the treatment of diabetic skin ulcer provided by the present embodiment comprises the following steps:

[0088] (a) After soaking each raw material in water for 30 minutes, after boiling on high heat, change to low heat for 30 minutes, filter to obtain a water decoction, and decoct the dregs obtained by filtering for the second time (the second decoction step is the same second decoction)...

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Abstract

The invention provides a traditional Chinese medicine composition for treating diabetic skin ulcer and a preparation method thereof, and relates to the technical field of traditional Chinese medicinecompositions. The traditional Chinese medicine composition is mainly prepared from unprocessed radix astragali, roasted Rhizoma Atractylodis Macrocephalae, poria cocos, cinnamon, radix aconiti carmichaeli, Cornu cervi degelatinatum, pawpaw, semen brassicae, cultivated land, Angelica sinensis, radix glehniae and the like. By defining the specific consumption of the raw materials, the compatibilityof raw materials is scientific and reasonable, the effect ingredients of the raw materials supplement each other and complement each other, the obtained traditional Chinese medicine composition can improve blood circulation of the diabetic skin ulcer part, tissue growth and repairing are facilitated, skin regeneration at the affected part is promoted, wound healing is accelerated, and the good treatment effect is achieved for diabetic skin ulcer. The invention further provides the preparation method of the traditional Chinese medicine composition for treating diabetic skin ulcer. The preparation method is simple and easy to implement and suitable for industrial large-scale production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating diabetic skin ulcers and a preparation method thereof. Background technique [0002] Diabetes is a group of metabolic diseases characterized by hyperglycemia. The long-term high blood sugar in diabetes will lead to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. [0003] Diabetic skin ulcer is a complication of diabetes. It mostly occurs on the feet of patients, so it is also called diabetic foot. , will directly affect the patient's diabetes treatment effect, and even lead to amputation and death. At present, there are many medicines for treating diabetic skin ulcers, but the therapeutic effect is not satisfactory. [0004] In view of this, the present invention is proposed to solve at least one of the above technical pro...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P17/02A61P3/10A61K35/32
CPCA61K35/32A61K36/076A61K36/23A61K36/232A61K36/284A61K36/31A61K36/37A61K36/481A61K36/54A61K36/704A61K36/714A61K36/732A61K36/804A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P3/10A61P17/02A61K2300/00
Inventor 李萍何秀娟张金超刘青武陈佳
Owner 北京市中医研究所
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