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Medical cold application plaster and preparation method thereof

A cold compress and preparation process technology, applied in the field of medical supplies, can solve the problems of unsatisfactory water retention and moisturizing performance of medical cold compress, unfavorable drug transdermal absorption, poor skin affinity, etc. Strong anti-aging effect

Inactive Publication Date: 2019-09-17
安徽宝华药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The medical cold compress described in this invention has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and dispelling dampness and numbness. The treatment of soft tissue injury and soreness, but the water retention and moisturizing performance of the medical cold compress of the invention is not ideal, and it is easy to produce irritation to the skin after application, and has poor affinity with the skin, which is not conducive to the transdermal absorption of drugs

Method used

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  • Medical cold application plaster and preparation method thereof
  • Medical cold application plaster and preparation method thereof
  • Medical cold application plaster and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A medical cold compress, comprising several cold compress monomers and connecting strips, the cold compress monomers sequentially include a backing layer, a gel layer and a cover layer from top to bottom, and the raw materials of the gel layer are by weight Including: 25 parts of carbomer, 6 parts of sodium polyacrylate, 3 parts of ethanol, 2 parts of moisturizing agent, 4 parts of penetration enhancer, 15 parts of Chinese herbal medicine extract, 60 parts of purified water;

[0040] Wherein, the moisturizing agent is composed of sodium hyaluronate and decyl glucoside in a mass ratio of 3:2; the penetration enhancer is composed of N-acetylproline amyl alcohol ester and menthol in a mass ratio of 1: 5 compounded.

[0041] The preparation process of the Chinese herbal medicine extract is:

[0042] (1) Weigh the following Chinese medicine raw materials in parts by weight: Drynaria 6 parts, Panax notoginseng 3 parts, Nuxychium 4 parts, Saffron 3 parts, Wood beetle 2 parts,...

Embodiment 2

[0052] A medical cold compress, comprising several cold compress monomers and connecting strips, the cold compress monomers sequentially include a backing layer, a gel layer and a cover layer from top to bottom, and the raw materials of the gel layer are by weight Including: 30 parts of carbomer, 7 parts of sodium polyacrylate, 4 parts of ethanol, 3 parts of moisturizing agent, 5 parts of penetration enhancer, 18 parts of Chinese herbal medicine extract, 70 parts of purified water;

[0053] Wherein, the moisturizing agent is composed of sodium hyaluronate and decyl glucoside in a mass ratio of 3:2; the penetration enhancer is composed of N-acetylproline amyl alcohol ester and menthol in a mass ratio of 2: 5 compounded.

[0054] The preparation process of the Chinese herbal medicine extract is:

[0055] (1) Weigh the following Chinese medicine raw materials in parts by weight: 7 parts of drynariae, 4 parts of Sanqi, 5 parts of Nuxychia, 4 parts of saffron, 3 parts of ground be...

Embodiment 3

[0065] A medical cold compress, comprising several cold compress monomers and connecting strips, the cold compress monomers sequentially include a backing layer, a gel layer and a cover layer from top to bottom, and the raw materials of the gel layer are by weight It includes: 40 parts of carbomer, 8 parts of sodium polyacrylate, 5 parts of ethanol, 4 parts of moisturizing agent, 7 parts of penetration enhancer, 20 parts of Chinese herbal medicine extract, and 80 parts of purified water;

[0066] Wherein, the moisturizing agent is composed of sodium hyaluronate and decyl glucoside in a mass ratio of 3:2; the penetration enhancer is composed of N-acetylproline amyl alcohol ester and menthol in a mass ratio of (2 : 5 compounded.

[0067] The preparation process of the Chinese herbal medicine extract is:

[0068] (1) Weigh the following Chinese medicine raw materials in parts by weight: Drynaria 8 parts, Panax notoginseng 5 parts, Nuxychium 6 parts, Saffron 5 parts, Wood beetle ...

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Abstract

The invention belongs to the technical field of medical supplies and particularly to a medical cold application plaster. The medical cold application plaster comprises multiple single cold application bodies and connecting strips, the single cold application bodies and the connecting strips are of an integrated structure, every two adjacent single cold application bodies are separated by the corresponding connecting strip, and strip-shaped holes are uniformly formed in the connecting strips; each single cold application body sequentially includes a backing layer, a gel layer and a covering layer from top to bottom. By optimizing compositions of the gel layers and the ratio of the components, the obtained gel layers have good air permeability and no irritation or sensitization and can be repeatedly peeled off and applied, and water and moisture of the skin can be retained to prevent skin aging; at the same time, the medical cold application plaster has high affinity to the skin and is also conducive to transdermal absorption of drugs, wherein ingredients of the drugs are mainly derived from Chinese herbal extracts, and raw materials in the Chinese herbal extracts are in coordinated compatibility and mutual gain to achieve the effects of promoting blood circulation, dispelling blood stasis, dredging collaterals and relieving pain. The medical cold application plaster has a good curative effect, takes effect quickly and is high in cure rate and free of toxic and side effect.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to a medical cold compress and a preparation method thereof. Background technique [0002] The medical cold compress is improved according to the traditional cold compress method. The TDDS new drug release system prepared on the basis of polymer gel is the core, and it is composed of a backing layer, a gel layer, and an anti-adhesive layer. Through the vaporization of the water contained in the polymer gel and the natural cooling ingredients to take away the heat, local cooling can be achieved. The drug ingredients in it are combined with the hydrogel, and through hydration, the drug ingredients can quickly penetrate the fat layer. It penetrates into the subcutaneous tissue, directly reaches the lesion, acts on the affected area, and achieves the effects of cold compress to relieve pain, percutaneous absorption, and sustained release. Medical cold compresses ca...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/70A61K47/26A61K47/32A61K47/36A61P29/00A61F7/02A61K31/045A61K35/64
CPCA61F7/02A61F2007/0219A61K9/7023A61K31/045A61K35/64A61K36/126A61K36/232A61K36/258A61K36/56A61K36/605A61K36/61A61K36/88A61K47/26A61K47/32A61K47/36A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61P29/00A61K2300/00
Inventor 张玉丽李丽娜
Owner 安徽宝华药业有限公司