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Animal genetic vaccine based on nanotechnology

A gene vaccine and nanotechnology technology, applied in the field of animal gene vaccines, can solve the problems of insignificant vaccination effect, increase the cost of raising animals, infection of infectious or non-infectious diseases, etc., to ensure the prevention effect and effect, and improve the prevention effect , the effect of improving stability

Pending Publication Date: 2019-10-08
商丘美兰生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] But the inoculation effect of the animal vaccine in the above-mentioned prior art is not remarkable, and often the animal after vaccinating can be infected with infectious disease as usual, can not avoid the risk of animal infection infectious or non-infectious disease completely, not only improved raising The cost of animals, and animals carrying infectious diseases also pose a great threat to human health

Method used

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  • Animal genetic vaccine based on nanotechnology
  • Animal genetic vaccine based on nanotechnology
  • Animal genetic vaccine based on nanotechnology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Such as figure 1 As shown, an animal gene vaccine based on nanotechnology includes 0.1-20 parts of emulsifier, 0.01-10 parts of polymer, 0.01-5 parts of immune enhancer, 0-4 parts of co-emulsifier and animal vaccine.

[0057] The emulsifier is one or more of nonionic emulsifiers such as xylitol, maltitol, and sorbitan. The polymer is a natural polymer or a synthetic polymer; further, it is one or more of mannan, polyethylene glycol, polyglycerin, polymethacrylate, and polylactic-glycolic acid.

[0058] The immune enhancer is a bacterial immune enhancer, specifically BCG. The immune enhancer is a product of human or animal immune system, specifically thymosin, transfer factor, interferon, interleukin and the like.

[0059] The co-emulsifier is straight-chain or straight-chain fatty acid or fatty alcohol. The animal vaccine is an inactivated vaccine for bird flu, foot-and-mouth disease, bovine epidemic fever or dental caries vaccine.

[0060] The dental caries vaccine...

Embodiment 2

[0072] An animal genetic vaccine based on nanotechnology, comprising 0.1-20 parts of emulsifier, 0.01-10 parts of polymer, 0.01-5 parts of immune enhancer, 0-4 parts of co-emulsifier, 10-70 parts of vegetable oil for injection, Animal vaccine 0.01-5 parts.

[0073] The emulsifier is one or more of nonionic emulsifiers such as xylitol, maltitol, and sorbitan. The polymer is a natural polymer or a synthetic polymer; further, it is one or more of mannan, polyethylene glycol, polyglycerin, polymethacrylate, and polylactic-glycolic acid.

[0074] The immune enhancer is a bacterial immune enhancer, specifically BCG. The immune enhancer is a product of human or animal immune system, specifically thymosin, transfer factor, interferon, interleukin and the like.

[0075] The co-emulsifier is straight-chain or straight-chain fatty acid or fatty alcohol. The animal vaccine is an inactivated vaccine for bird flu, foot-and-mouth disease, bovine epidemic fever or dental caries vaccine.

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Abstract

The invention discloses an animal genetic vaccine based on nanotechnology, which comprises the following components: 0.1-20 parts of an emulsifier, 0.01-10 parts of a polymer, 0.01-5 parts of an immune enhancer, 0-4 parts of an auxiliary emulsifier, and 0.01-5 parts of an animal vaccine. The animal genetic vaccine of the invention improves the effect of the animal genetic vaccine, achieves a significant reduction in the incidence of infectious or non-infectious diseases on the animal, and improves the preventive effect of the vaccine.

Description

technical field [0001] The invention belongs to the technical field of animal vaccines, in particular to an animal gene vaccine based on nanotechnology. Background technique [0002] With the development of the economy, whether it is pet animals or artificially raised food animals, the animal industry has experienced great development. In the process of raising animals, they are faced with the threat of various infectious diseases or non-infectious diseases. In order to improve the immunity of animals and reduce the incidence of various infectious diseases, various animal vaccines have been developed. [0003] In the prior art, in order to improve the immunity of animals and reduce the incidence of various infectious diseases or non-infectious diseases, the commonly used animal vaccines are as follows: [0004] Chinese patent application 201810259585.7 discloses a marine mammal vaccine whose active ingredient is an inactivated marine mammal Pseudomonas aeruginosa antigen. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/135A61K39/145A61K39/12A61K39/09A61K39/39A61K47/26A61P31/16A61P31/14A61P1/02F25D11/00F25D25/02
CPCA61K39/12A61K39/09A61K39/39A61K47/26A61P31/16A61P31/14A61P1/02F25D11/00F25D25/027A61K2039/53A61K2039/552A61K2039/55594C12N2760/16134C12N2770/32134
Inventor 韩运涛姚奋卯王书丽张宁孟祥焦金英李国辉黄向丽
Owner 商丘美兰生物工程有限公司
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