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Preparation method of flavone-rich hypoglycemic papaya lozenge

A technology of Chuan papaya and flavonoids, which is applied in the field of preparation of hypoglycemic Chuan papaya lozenges, can solve problems such as toxic and side effects, increased diabetes, and difficulty in research and development, and achieve the effect of being easy to accept and good in taste

Inactive Publication Date: 2019-10-18
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to develop a pure natural hypoglycemic Chuan papaya compound with multi-purpose, multi-target, and small side effects in order to solve the problems of current chemical drugs for treating diabetes with toxic and side effects, difficulty in research and development, and increasing diabetes patients. lozenge

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Purchase appropriate amount of high-quality fresh papaya, peach, lemon, apple, and passion fruit, remove the core, stem, etc., clean them, freeze-dry them for 48 hours, and crush them; purchase β-cyclodextrin, pregelatinized starch, and xylitol , crushed separately; purchase an appropriate amount of dried rose tea, and crush it. Ultrasonic extraction of flavonoids in papaya and rose tea, the conditions are solid-liquid ratio 1:15, 60% ethanol at 50 ℃, ultrasonic 60min, ultrasonic power 400w, rotary evaporation to 1 / 5 of the volume, freeze-dried to obtain the extract. Various raw materials were passed through a 40-mesh sieve, and the sieved papaya 15g, peach 8g, lemon 8g, apple 10g, passion fruit 8g, rose tea 3g, β-cyclodextrin 6g, pregelatinized starch 6g, Xylitol 15g, fully mixed to obtain the raw material, the raw material is placed in a special mold and pressed into tablets to obtain the finished product.

Embodiment 2

[0011] Purchase appropriate amount of high-quality fresh papaya, lemon, apple, strawberry, and passion fruit, remove the core, stem, etc., clean them, freeze-dry them for 48 hours, and crush them; purchase β-cyclodextrin, pregelatinized starch, and xylitol , crushed separately; purchase dry Qingqian willow and lotus leaves in appropriate amounts, and crush them separately. Ultrasonic extraction of flavonoids from papaya, papaya papaya, and lotus leaves. The conditions are solid-liquid ratio 1:15, 60% ethanol at 50°C, ultrasonic 60min, ultrasonic power 400w, rotary evaporation to 1 / 5 of the volume, freeze-dried to obtain extraction thing. Various raw materials were passed through a 40-mesh sieve, and the sieved Chuan papaya 20g, lemon 6g, apple 10g, strawberry 6g, passion fruit 6g, Qingqian willow 5g, lotus leaf 5g, β-cyclodextrin 15g, pre- 7g of gelatinized starch and 8g of xylitol are fully mixed to obtain the raw materials, and the raw materials are placed in a special mold...

Embodiment 3

[0013] Purchase high-quality fresh papaya, peaches, lemons, apples, and strawberries in appropriate amounts, remove the cores and stems, clean them, freeze-dry them for 48 hours, and crush them; purchase β-cyclodextrin, pregelatinized starch, and xylitol. Pulverize separately; purchase appropriate amount of dried rose tea and lotus leaves, and pulverize them separately. Ultrasonic extraction of flavonoids from Chuan papaya, rose tea, Qingqian willow, and lotus leaves. The conditions are solid-liquid ratio 1:15, 60% ethanol at 50°C, ultrasonic 60min, ultrasonic power 400w, and freeze when the volume is 1 / 5 by rotary evaporation Dry to obtain the extract. Various raw materials were passed through a 40-mesh sieve, and the sieved papaya 15g, peach 10g, lemon 5g, apple 5g, strawberry 5g, rose tea 3g, lotus leaf 3g, β-cyclodextrin 10g, pregelatinized 7g of starch and 20g of xylitol are fully mixed to obtain the raw materials, and the raw materials are placed in a special mold and p...

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Abstract

The invention relates to a preparation method of a flavone-rich hypoglycemic papaya lozenge. The hypoglycemic lozenge is prepared from papayas, passion fruits, rose tea, cyclocarya paliurus, lotus leaves, peaches, lemons, apples, strawberries, xylitol, beta-cyclodextrin and pregelatinized starch, wherein a formula of the lozenge includes 15-20% of the papayas, 10% of the passion fruits, 3-6% of the rose tea, 3-6% of the cyclocarya paliurus, 3-6% of the lotus leaves, 5-10% of the peaches, 5-10% of the lemons, 5-10% of the apples, 5-10% of the strawberries, 15% of the beta-cyclodextrin and the balance the xylitol, and the total volume of the lozenge is counted as 100%. The innovation of the hypoglycemic lozenge lies in that multiple raw materials containing the flavone component are extracted and added into the lozenge, a plurality of natural products are selected, the proportion is optimized, a synergistic effect of active components is achieved to promote insulin secretion, and meanwhile, the hypoglycemic lozenge has the functions of resisting oxidation and reducing blood sugar and blood fat. Papaya flavone and cyclocarya paliurus are used as main materials, and the fruits rich inpolyphenol compounds are used as auxiliary materials, so that the lozenge has the advantages of excellent blood sugar reduction function, good taste, small toxic and side effects, massive acting targets and the like.

Description

technical field [0001] The invention belongs to the field of health food processing, and relates to a preparation method of flavonoid-rich papaya buccal tablets. Background technique [0002] Diabetes is the third most common disease after tumors and cardiovascular diseases. Due to unhealthy living habits and various pressures, young people are suffering from diabetes, which seriously affects the quality of life. Toxic and side effects caused by drug treatment, such as gastrointestinal reactions, edema, heart, liver and kidney dysfunction, etc. Because natural products have the characteristics of multiple pathways, multiple targets, and few side effects, medical workers at home and abroad have shifted the goal of treating diabetes from chemical drugs to screening active ingredients for lowering blood sugar from natural products, giving full play to the role of natural active ingredients in the treatment of diabetes. and its unique advantages in complications. [0003] Chu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L19/00A23P10/28
CPCA23L33/105A23L19/01A23P10/28A23V2002/00
Inventor 王振宇王佳慧赵梦雅刘双韩晓旭
Owner HARBIN INST OF TECH
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