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Plasma protein isolate A immune adsorption device
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A plasma separation and immunoadsorption technology, applied in the field of medical devices, can solve the problems of manual operation errors, easy to nourish bacteria, and can not guarantee the patient's safe treatment.
Inactive Publication Date: 2019-12-31
THE FIRST PEOPLES HOSPITAL OF CHANGZHOU
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[0003] The existing protein A immunoadsorption device for plasma separation cannot be operated automatically when eluting and regenerating the adsorption column during the treatment of patients, which may easily lead to manual operation errors. Not only cannot the safe treatment of patients be guaranteed, but also The work intensity of the medical staff is high, its safety performance is poor, the surface is easy to nourish bacteria, and the hygienic condition is poor
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Embodiment 1
[0050] A plasma separation protein Aimmunoadsorption device, such as figure 1 As shown, it includes arterial end puncture needle 1, blood pump 3, arterial jug 4, plasma separator 6, first connecting pipe 7, first tee 8, plasma pump 9, plasma jug 26, adsorption column 28, second three Tong 30, second connecting tube 31, venous pot 5, puncture needle 2 at the venous end, and adsorption column flushing unit;
[0051] Such as figure 1 As shown, the liquid inlet of the blood pump 3 is fixedly communicated with one end of the arterial puncture needle 1 through a pipeline, and the upper end of the arterial jug 4 is fixedly communicated with the liquid outlet of the blood pump 3 through a pipeline. , the upper end of the plasma separator 6 is fixedly communicated with the bottom end of the arterial jug 4 through a pipe, one end of the first connecting pipe 7 is fixedly communicated with the bottom end of the plasma separator 6, and the second The left port of a tee 8 is fixedly com...
Embodiment 2
[0076] The difference from Example 1 is that the outer surface of the box body 37 is also provided with a protective layer, and the protective layer is prepared by the following method:
[0077] Take the following raw materials and weigh them by weight: 16 parts of epoxy resin, 8 parts of calciumcarbonatepowder, 10 parts of copperoxidepowder, 12 parts of nano-silver powder, 8 parts of titanium dioxide powder, 10 parts of acrylic emulsion, 2 parts of alcohol ester twelve, three 2 parts of ethanolamine, 1 part of emulsified silicone oil and 30 parts of water;
[0078] S1. Add the weighed acrylic emulsion, alcohol ester dodeca, triethanolamine, emulsified silicone oil and water into the mixer and stir for 15 minutes at a stirring speed of 500r / min to prepare a mixed solution;
[0084] The difference with embodiment 2 is the preparation of protective layer, and its specific preparation method is as follows:
[0085] Take the following raw materials and weigh them by weight: 20 parts of epoxy resin, 9 parts of calciumcarbonate powder, 12 parts of copperoxide powder, 14 parts of nano-silver powder, 9 parts of titanium dioxide powder, 13 parts of acrylic emulsion, 3 parts of alcohol ester twelve, three 3 parts of ethanolamine, 2 parts of emulsified silicone oil and 35 parts of water;
[0086] S1. Add the weighed acrylic emulsion, alcohol ester dodeca, triethanolamine, emulsified silicone oil and water into the mixer and stir for 18 minutes at a stirring speed of 550r / min to prepare a mixed solution;
[0087] S2, adding epoxy resin, calcium carbonate powder, copper oxide powder, nano-silver powder and titanium dioxide powder into a pulverizer for pulverization until the particle diameter of the material is not greater than 100nm to obtain a mixed powder...
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Abstract
The invention discloses a plasmaprotein isolate A immune adsorption device. The device comprises an artery end puncture needle, a blood pump, an artery pot, a plasma separator, a first connecting pipe, a first tee joint, a plasma pump, a plasma pot, an adsorption column, a second tee joint, a second connecting pipe, a vein pot, a vein end puncture needle and an adsorption column flushing unit, the adsorption column flushing unit comprises a third connecting pipe, a pre-flushing liquid storagebottle, an eluent storage bottle, an equilibrium liquid storagebottle, a fourth connecting pipe, a waste liquid discharging pipe, a waste liquid collecting barrel, a first electromagnetic valve, a second electromagnetic valve and a third electromagnetic valve. According to the invention, the purposeof eluting and regenerating the adsorption column in treatment of a patient can be achieved, automatic operation can be realized, the phenomenon that errors are easily caused by manual operation canbe avoided, the patient can be effectively ensured to be safely treated, the working intensity of medical personnel can be effectively reduced, the safety performance is better, and the device is clean and sanitary.
Description
technical field [0001] The invention relates to the technical field of medical equipment, more specifically, it relates to a plasma isolate protein A immunoadsorption device. Background technique [0002] Plasma adsorption is that after the blood is drawn out, it first enters the plasma separator to separate the formed components of the blood (blood cells, platelets) from the plasma, and the formed components are returned to the patient, and then the plasma enters the adsorber (adsorption column) to absorb and remove some specific substances. After absorption, the plasma is returned to the patient. Plasma adsorption is mainly divided into two categories according to the characteristics of the adsorbent. One is molecular sieve adsorption, which uses the principle of molecular sieve to non-specifically adsorb substances corresponding to the charge and molecular size through the charge and pores carried by the adsorbent, such as Activated carbon, resin, carbonized resin and ca...
Claims
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Application Information
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