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A new type of artificial skin

A technology of artificial skin and shaping method, which is applied in the fields of prosthesis, medical science, etc., can solve the problem of high personnel and achieve the effect of improving skin ulceration

Active Publication Date: 2021-12-10
HUNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] In recent years, due to the development of protective measures and the standardization of the industrial system, fewer and fewer people died on the spot in accidents, but the number of people who died of various sequelae or even ineffective rescue due to the complicated treatment process was too high. How to apply the protection and treatment that is most conducive to the recovery of human body functions and postoperative healing after skin injury has become an urgent problem to be solved

Method used

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  • A new type of artificial skin
  • A new type of artificial skin
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Experimental program
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Embodiment Construction

[0024] Below in conjunction with implementing regulation this patent is described further.

[0025] 1) How to make multi-layer artificial skin:

[0026] Hyaluronic acid layer: Deionized water, formic acid and dimethylformamide are configured as a solution in a weight ratio of 1:2:1, and then 1 wt% of hyaluronic acid dry powder is dissolved to make a solution, and it is rapidly formed into an approximate circle shaped fiber layer.

[0027] PLGA layer: Dimethylformamide and tetrahydrofuran are configured as a solution at a weight ratio of 1:3, and then PLGA dry powder is dissolved at 0.3g / ml to make a solution, which is placed on the hyaluronic acid layer, and the fiber diameter is about 400nm- Between 1100nm.

[0028] Bacterial cellulose layer: the bacterial cellulose film produced by Acetobacter xylinum was sterilized, soaked in 1% NaOH solution, heated and cleaned in a water bath, and stored in ethanol. When in use, cut it to an appropriate size and dry it to a slightly mo...

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Abstract

This product is aimed at the field of tissue engineering and medical repair, using highly biocompatible materials for the production of fibrous membrane artificial skin. It is suitable for the immediate treatment of skin damage and chronic ulcers caused by various disasters. This product uses rapid prototyping technology to prepare artificial skin with multi-layer structure, which can change the structure and function according to the specific injury. Bacterial cellulose, PLGA, and hyaluronic acid are used as raw materials to imitate the real skin structure and maintain the stability of the wound microenvironment. Skin ulcers and difficult-to-heal problems caused by dysfunction, etc.

Description

technical field [0001] This patent is aimed at the field of tissue engineering and medical repair, using high biocompatibility materials to make fibrous membrane artificial skin, temporarily replacing defective skin, enhancing the immune system, regulating the temperature and humidity of the wound, and preventing microbial infection and inflammation. The flexible use of this product can provide immediate treatment to the injured after various accidents, so as to save time for a more complete treatment plan, or suppress the further impact of the wound on the body so that the injured can quickly recover their mobility. It can heal less serious skin lesions and has special effects on skin ulcers caused by chronic diseases. Background technique [0002] In recent years, due to the development of protective measures and the standardization of the industrial system, fewer and fewer people died on the spot in accidents, but the number of people who died of various sequelae or even ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/40A61L27/60A61L27/20A61L27/18A61L27/38A61L27/54A61L27/50
CPCA61L27/60A61L27/20A61L27/18A61L27/3804A61L27/54A61L27/50A61L2300/412C08L5/08C08L67/04C08L1/02
Inventor 谭志凯王建王昊明
Owner HUNAN UNIV
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