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Formula powder used for phenylketonuria patient, and preparation method for formula powder

A kind of technology of phenylketonuria and formula powder, applied in the field of formula powder and preparation thereof

Pending Publication Date: 2020-01-17
杨国民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, since phenylalanine is contained in general food, milk powder and breast milk, in order to deal with phenylketonuria, it is necessary to control the patient's diet and limit the intake of phenylalanine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The formula powder for patients with phenylketonuria of the present invention is prepared from the following components by mass percentage: vegetable oil fat powder 82.26%, compound amino acid 14%, nucleotide 0.03%, docosahexaenoic acid (DHA ) 0.05%, arachidonic acid (ARA) 0.09%, essence 0.1%, multivitamins 0.57% and multiminerals 2.9%, the formula powder does not contain phenylalanine.

[0032] The compound amino acid is composed of the following components by mass percentage: L-alanine 0.2-0.4%, L-arginine 0.2-0.5%, L-aspartic acid 0.7-1.0%, L-cystine 0.15% -0.35%, L-Glutamine 1.6-2.0%, Glycine 0.1-0.3%, L-Histidine 0.3-0.5%, L-Isoleucine 0.8-1.1%, L-Leucine 1.4-1.6% , L-lysine hydrochloride 0.8-1.2%, L-methionine 0.2-0.4%, L-proline 0.8-1.1%, L-serine 0.3-0.6%, L-threonine 0.5-0.7% , L-tryptophan 0.2-0.4%, L-tyrosine 0.8-1.2% and L-valine 0.8-1.2%.

[0033] The vegetable oil fat powder is prepared by spray drying solid glucose syrup, pregelatinized starch, fatty ac...

Embodiment 2

[0047] The formula powder for patients with phenylketonuria of the present invention is prepared from the following components in mass percentage:

[0048] Vegetable oil fat powder 79.883%, compound amino acid 14%, fructo-oligosaccharide (Fos) 0.1%, galacto-oligosaccharide (Gos) 0.9%, nucleotide 0.05%, docosahexaenoic acid (DHA) 0.0525%, di 0.0945% arachidonic acid (ARA), 0.3% essence, 0.12% multivitamin and 4.5% multivitamin, and the formula powder does not contain phenylalanine.

[0049] The compound amino acid is composed of the following components by mass percentage: L-alanine 0.2-0.4%, L-arginine 0.2-0.5%, L-aspartic acid 0.7-1.0%, L-cystine 0.15% -0.35%, L-Glutamine 1.6-2.0%, Glycine 0.1-0.3%, L-Histidine 0.3-0.5%, L-Isoleucine 0.8-1.1%, L-Leucine 1.4-1.6% , L-lysine hydrochloride 0.8-1.2%, L-methionine 0.2-0.4%, L-proline 0.8-1.1%, L-serine 0.3-0.6%, L-threonine 0.5-0.7% , L-tryptophan 0.2-0.4%, L-tyrosine 0.8-1.2% and L-valine 0.8-1.2%.

[0050] The vegetable oil f...

Embodiment 3

[0064] The formula powder for patients with phenylketonuria of the present invention is prepared from the following components in mass percentage:

[0065] Vegetable oil fat powder 88.296%, compound amino acid 8%, nucleotide 0.035%, docosahexaenoic acid (DHA) 0.045%, arachidonic acid (ARA) 0.081%, essence 0.5%, multivitamin 0.087% and Multimineral 2.956%, the formula does not contain phenylalanine.

[0066] The compound amino acid is composed of the following components by mass percentage: L-alanine 0.2-0.4%, L-arginine 0.2-0.5%, L-aspartic acid 0.7-1.0%, L-cystine 0.15% -0.35%, L-Glutamine 1.6-2.0%, Glycine 0.1-0.3%, L-Histidine 0.3-0.5%, L-Isoleucine 0.8-1.1%, L-Leucine 1.4-1.6% , L-lysine hydrochloride 0.8-1.2%, L-methionine 0.2-0.4%, L-proline 0.8-1.1%, L-serine 0.3-0.6%, L-threonine 0.5-0.7% , L-tryptophan 0.2-0.4%, L-tyrosine 0.8-1.2% and L-valine 0.8-1.2%.

[0067] The vegetable oil fat powder is prepared by spray drying solid glucose syrup, pregelatinized starch, fa...

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Abstract

The invention aims to disclose a formula powder used for a phenylketonuria patient, and a preparation method for the formula powder. The formula powder is prepared from the following ingredients in parts by weight: 60-90% of plant oil fatty powder, 8-20% of compound amino acid, 0-6.45% of Fos (Fructo oligosaccharide), 0-6.45% of Gos (galacto-oligosaccharide), 0.012-0.058% of nucleotide, 0.044-0.13% of vitamin complex and 1.195-4.717% of complex mineral substance, and does not contain phenylalanine. Compared with the prior art, fat, carbohydrates, amino acids, vitamins, mineral substances and the like are taken as a basic composition, a proportion is scientific, and the growth and development requirements of infants can be met. The plant oil fatty powder contains the fat and the carbohydrates, energy is provided for organisms, the compound amino acid supplements the growth and development requirements of a human body with necessary amino acids, in addition, phenylalanine is not added, the accumulation of alanine and a ketonic acid thereof is not generated, the intake of the amino acids of a patient is guaranteed, the normal metabolism of the amino acid of the organisms is maintained, and the purposes of the formula powder disclosed by the invention is realized.

Description

technical field [0001] The invention relates to a formula powder and a preparation method thereof, in particular to a formula powder for phenylketonuria patients and a preparation method thereof. Background technique [0002] Phenylketonuria (Phenylketonuria, PKU) is a common disorder of amino acid metabolism. It is due to an enzyme defect in the phenylalanine (PA) metabolic pathway, which prevents phenylalanine from being converted into tyrosine, resulting in phenylalanine. Amino acids and their ketoacids accumulate and are excreted in large quantities in the urine. [0003] Phenylketonuria is relatively common among hereditary amino acid metabolism deficiency diseases, with an incidence rate of 1 / 10000. Its mode of inheritance is autosomal recessive. The clinical manifestations are heterogeneous, and the main clinical features are mental retardation, psychoneurological symptoms, eczema, skin scratch signs, depigmentation, rat odor, etc., and abnormal EEG. [0004] If ph...

Claims

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Application Information

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IPC IPC(8): A23L33/12A23L33/125A23L33/15A23L33/155A23L33/16A23L33/175
CPCA23L33/12A23L33/175A23L33/125A23L33/15A23L33/155A23L33/16A23V2002/00A23V2200/30A23L33/115A23L33/00A23L33/10
Inventor 杨国民
Owner 杨国民
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