Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Waterproof easy-to-peel wound dressing and preparation method thereof

A wound dressing and easy-peeling technology, applied in medical science, bandages, etc., can solve the problems of non-waterproof wound dressing and not allowing patients to bathe, etc., and achieve a good separation effect

Inactive Publication Date: 2020-01-17
RENMIN UNIVERSITY OF CHINA
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Fourth, many wound dressings are not waterproof, which brings about the problem that patients are not allowed to take a bath in order to avoid wound infection after surgery

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Waterproof easy-to-peel wound dressing and preparation method thereof
  • Waterproof easy-to-peel wound dressing and preparation method thereof
  • Waterproof easy-to-peel wound dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] 1.1g monomer acrylic acid (in formula I, R 1 is H, n is 0), 0.02g N,N'-methylenebisacrylamide (crosslinking agent) and 0.02g hydrotalcite (strengthening agent) are dissolved in 10ml water, stirred at 60°C for 1h, passed into Nitrogen, the purpose is to feed nitrogen to remove oxygen in the reactor and water. At the same time, configure 10 mg / ml of ammonium persulfate solution (initiator), drop the initiator dropwise into the reactor containing the monomer, and after 2 hours, carry out high-pressure sterilization to obtain a hydrogel dressing with good adhesion , to treat the non-adhesive skin surface, spray physiological saline solution at room temperature, the waterproof effect is as follows figure 2 As shown, when water is dripped on the wound dressing, the water droplets stay on the surface of the wound dressing and do not penetrate into the wound dressing.

[0042] In the above examples, based on the total mass of monomeric acrylic acid, N,N'-methylenebisacrylami...

Embodiment 2

[0047] 1.1g monomeric acrylic acid (R 1 is H, n is 0), 0.02g N,N'-methylenebisacrylamide (crosslinking agent) and 0.02g hydrotalcite (strengthening agent) are dissolved in 10ml water, stirred at 60°C for 1h, passed into Nitrogen, the purpose is to feed nitrogen to remove oxygen in the reactor and water. At the same time, configure 10 mg / ml of ammonium persulfate solution (initiator), drop the initiator dropwise into the reactor containing the monomer, and after 2 hours, carry out high-pressure sterilization to obtain a hydrogel dressing with good adhesion ; Treat the non-adhesive skin surface of the prepared hydrogel dressing, and spray ferric chloride solution at normal temperature to achieve waterproof effect.

[0048] The hydrogel dressing prepared in this example can adhere well to the skin.

Embodiment 3

[0050] 1.1 g monomeric cinnamic acid (R 1is phenyl, n is 0), 0.06g N,N'-methylenebisacrylamide (crosslinking agent) and 0.02g hydrotalcite (strengthening agent) are dissolved in 10ml water, stirred at 60°C for 1h, passed Nitrogen is introduced to remove the oxygen in the reactor and water. At the same time, configure 10 mg / ml of potassium persulfate solution (initiator), drop the initiator dropwise into the reactor containing the monomer, and after 2 hours, carry out high-pressure sterilization to obtain a hydrogel dressing with good adhesion ; Treat the non-adhesive skin surface of the prepared hydrogel dressing, and spray ferric chloride solution at normal temperature to achieve waterproof effect.

[0051] The hydrogel dressing prepared in this example can adhere well to the skin.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention discloses a waterproof easy-to-peel wound dressing and a preparation method thereof. The preparation method comprises: in an inert atmosphere, in the presence of a cross-linking agent and an initiator, carrying out a free radical polymerization reaction on a monomer in water to obtain the wound dressing, wherein the monomer has the following functional groups 1) and 2): 1) a carbon-carbon double bond, and 2) carboxyl or phenolic hydroxyl, and in a waterproof film forming process, the non-adhesive skin surface of the dressing is required to be sprayed with or soaked in a saline solution, and the saline solution is selected from physiological saline, a magnesium chloride solution, a ferric chloride solution, citric acid and the like. According to the invention, the waterproof easy-to-peel wound dressing can further comprise other common additives such as a sterilizing agent and the like in the field; and the surface of the hydrogel dressing of the invention is waterproof, and the hydrogel dressing can be well separated by soaking too much or a large amount of hydrogel dressing.

Description

technical field [0001] The invention relates to a waterproof and easy-to-peel wound dressing and a preparation method thereof. Background technique [0002] With the aging population and the widespread use of antiplatelet drugs to prevent cardiovascular events, wounds or extensive wound exposure are becoming more and more common in trauma or emergency surgery situations, and surgical dressing changes often encounter the challenge of wounds or wounds that are difficult to peel , Patients are faced with problems such as scabbing and pain when changing dressings after surgery, including burns, sprains, bedsores, abrasions, cuts, ulcers, surgical trauma, etc., threatening the safety of patients at all times. Ideally, use a waterproof easy-peel dressing. Hydrogel can provide a moist environment, and has antibacterial, antioxidative, antiviral and other effects. Medical hydrogel dressings have the functions of strong adhesion to wounds, pain relief, hemostasis and wound closure,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C08F220/06C08F220/04C08F222/38C08K3/22C08J3/075C08L33/02A61L26/00
CPCA61L26/0004A61L26/0014A61L26/008C08F220/04C08F220/06C08J3/075C08J2333/02C08K3/22C08L33/02C08F222/385
Inventor 孙迪刘杰
Owner RENMIN UNIVERSITY OF CHINA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com