Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for catalytically synthesizing anisole by using Na-NaOH/gamma-Al2O3

A technology of anisole and phenol, which is applied in the field of synthesis of anisole, can solve the problems of large amount of methylation reagents, high investment in equipment, and high cost of raw materials, and achieve the effects of good stability, good selectivity, and high activity

Pending Publication Date: 2020-02-21
YULIN UNIV
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this reaction is mostly carried out under high pressure, and the amount of methylating reagent is relatively large. Industrial production will result in high investment in equipment and high cost of raw materials, so that it has no cost advantage compared with the traditional dimethyl sulfate process.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for catalytically synthesizing anisole by using Na-NaOH/gamma-Al2O3

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Add phenol and dimethyl carbonate into the autoclave at a molar ratio of 1:3, and add 3% of the total mass of phenol and dimethyl carbonate in Na-NaOH / γ-Al 2 o 3 , under nitrogen protection at 190 ° C airtight reaction 2h. The reaction solution was detected by a gas chromatography spectrometer, and the conversion rate of phenol reached 98.52%, and the yield rate of anisole was 96.30%.

[0015] After the above reaction, directly centrifuge and recover Na-NaOH / γ-Al 2 o 3 proceed to the next reaction. See the reaction result figure 1 . Depend on figure 1 Visible, Na-NaOH / γ-Al 2 o 3 After repeated use 10 times, the conversion rate of phenol does not change substantially, and the yield of anisole does not change much at the beginning. After repeated use 6 times, it slightly decreases, but still remains above 90% overall, which shows that the catalyst of the present invention is reused. High activity and good stability.

Embodiment 2

[0017] Add phenol and dimethyl carbonate into the autoclave at a molar ratio of 1:2, and add 5% of the total mass of phenol and dimethyl carbonate in Na-NaOH / γ-Al 2 o 3 , under nitrogen protection at 180 ° C airtight reaction 3h. The reaction solution was detected by a gas chromatography spectrometer, and the conversion rate of phenol reached 81.85%, and the yield rate of anisole was 80.64%.

Embodiment 3

[0019] Add phenol and dimethyl carbonate into the autoclave at a molar ratio of 1:4, and add 5% of the total mass of phenol and dimethyl carbonate in Na-NaOH / γ-Al 2 o 3 , under nitrogen protection at 190 ° C airtight reaction 2h. The reaction solution was detected by a gas chromatography spectrometer, and the conversion rate of phenol reached 81.76%, and the yield rate of anisole was 80.75%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for catalytically synthesizing anisole by using Na-NaOH / gamma-Al2O3. The method comprises the following step: allowing solid superbase Na-NaOH / gamma-Al2O3 used as a catalyst to catalyze a reaction of phenol and dimethyl carbonate at 180 to 200 DEG C under the protection of nitrogen so as to synthesize the anisole. The method provided by the invention shows good reaction activity; the phenol conversion rate and anisole selectivity are high; meanwhile, the usage amount of the catalyst is small; and the catalyst has high reuse activity and good stability.

Description

technical field [0001] The invention belongs to the synthetic technical field of anisole, be specifically related to a kind of Na-NaOH / γ-Al 2 o 3 As a catalyst, it catalyzes the method of synthesizing anisole by reacting dimethyl carbonate and phenol. Background technique [0002] Anisole, also known as anisole, anisole, and methoxybenzene, is an important chemical raw material and organic synthesis intermediate, used to synthesize beer antioxidants, ethylene polymers, ultraviolet stabilizers, spices, insecticides, etc. , because of its special fragrance, people usually use it as an additive to soap or detergent, because it has a large dielectric constant and a high boiling point, and can be used as an excellent general reagent, initiator, solvent, thermostat filler, etc.; , because it can increase the octane number of gasoline, it can also be used as a gasoline additive instead of methyl tert-butyl ether. In recent years, the market demand for anisole has been increasing...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C41/16C07C43/205
CPCC07C41/16C07C43/205
Inventor 张智芳杨鹏任旭张璐吕波毕文强
Owner YULIN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com