Vitamin K1 injection and preparation method thereof

A technology for vitamins and injections, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., can solve the problems of poor stability, easy decomposition, and darkening of vitamin K1, and is suitable for industrial scale-up production, improving solubility, The effect of simple process
CN110876719AActive Publication Date: 2020-03-13ACADEMY OF MILITARY MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ACADEMY OF MILITARY MEDICAL SCI
Publication Date
2020-03-13

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Abstract

The invention relates to the field of medicines, and relates to a vitamin K1 injection and a preparation method thereof. In particular, the invention relates to a micelle solution and a preparation method thereof, and also relates to an injection containing the micelle solution and a preparation method thereof.
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Description

technical field

[0001] The invention relates to the field of medicine, in particular to the field of injection preparations. Background technique

[0002] The chemical name of vitamin K1 is 2-methyl-3-(3,7,11,15-tetramethylhexade-2-enyl)-1,4-naphthoquinone, and the molecular formula is C 31 h 46 o 2 , the molecular weight is 450.71, and its structural formula is shown in the following formula.

[0003]

[0004] Vitamin K1 is a yellow to orange-yellow, transparent and viscous liquid with an odorless or almost odorless odor. It is extremely unstable under light conditions and easily decomposed. Vitamin K1 is easily soluble in solvents such as chloroform, ether or vegetable oil, slightly soluble in ethanol, almost insoluble in water, and its refractive index is 1.525-1.528.

[0005] Vitamin K1 is an essential substance for the liver to synthesize prothrombin, and when it is deficient, it can cause coagulation disorders. When human blood lacks prothrombin, blood coagulat...

Claims

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