Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for producing fish peptide by using immobilized composite protease

A compound protease and protease technology, applied in the field of proteolysis, can solve the problems of low enzymatic hydrolysis efficiency and complicated enzymatic hydrolysis steps, and achieve the effects of simple preparation process, reduced production cost, and improved thermal stability

Active Publication Date: 2021-05-14
广东希普生物科技股份有限公司
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method uses two immobilized enzymes to carry out two-step enzymatic hydrolysis of squid minced meat, the enzymatic hydrolysis steps are relatively complicated, and the enzymatic hydrolysis efficiency is low

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The method for producing fish peptides using immobilized composite protease of the present embodiment comprises the following steps:

[0027] 1) Take 0.5 kg of gelatin and 2 kg of sodium alginate and dissolve them in 100 kg of water at a temperature of 60° C. to obtain a carrier solution.

[0028] 2) Add protease mixed solution to the carrier solution in step 1), the protease mixed solution is a mixture of alkaline protease and trypsin, the mass ratio of alkaline protease, trypsin and carrier solution is 4:2:100, stir to dissolve , to obtain a compound protease solution.

[0029] 3) drop the compound protease solution in step 2) to CaCl 2 Immobilized in the solution into particles with a particle size of 0.5-2.5mm, CaCl 2 CaCl in solution 2 The mass ratio to water is 1.5:100, stirring continuously during the immobilization process, the immobilization time is 30min, and the curing temperature is 25°C. After the immobilization is completed, filter with a 40-mesh sieve ...

Embodiment 2

[0032] The method for producing fish peptides using immobilized composite protease of the present embodiment comprises the following steps:

[0033] 1) Take 0.5 kg of gelatin and 2 kg of sodium alginate and dissolve them in 100 kg of water at a temperature of 60° C. to obtain a carrier solution.

[0034] 2) Add protease mixed solution to the carrier solution in step 1), the protease mixed solution is a mixture of alkaline protease and trypsin, the mass ratio of alkaline protease, trypsin and carrier solution is 4:2:100, stir to dissolve , to obtain a compound protease solution.

[0035] 3) drop the compound protease solution in step 2) to CaCl 2 Immobilized into particles with a particle size of 2-2.5mm in the solution, CaCl 2 CaCl in solution 2 The mass ratio to water was 2:100. Stir continuously during the immobilization process. The immobilization time was 50 minutes. The immobilization temperature was 28°C. Second-rate.

[0036] 4) Fresh fish and water are beaten and ...

Embodiment 3

[0038] The method for producing fish peptides using immobilized composite protease of the present embodiment comprises the following steps:

[0039] 1) Take 1 kg of gelatin and 2 kg of sodium alginate and dissolve them in 100 kg of water at a temperature of 60° C. to obtain a carrier solution.

[0040] 2) Add protease mixed solution to the carrier solution in step 1), the protease mixed solution is a mixture of alkaline protease and trypsin, the mass ratio of alkaline protease, trypsin and carrier solution is 6:4:100, stir to dissolve , to obtain a compound protease solution.

[0041] 3) drop the compound protease solution in step 2) to CaCl 2 Immobilized in the solution into particles with a particle size of 0.5-1.5 mm, CaCl 2 CaCl in solution 2The mass ratio to water was 2.5:100, stirring continuously during the immobilization process, the immobilization time was 30min, and the immobilization temperature was 22°C. After the immobilization was completed, the immobilized co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a method for producing fish peptides by using an immobilized composite protease. The method comprises the following steps: dissolving gelatin and sodium alginate in water to obtain a carrier solution, adding a protease mixed solution to the carrier solution, stirring and dissolving to obtain a composite protease solution , drop the compound protease solution into CaCl 2 Immobilize into microparticles in the solution, stir continuously in the immobilization process, filter to obtain immobilized composite enzyme particles after immobilization finishes, mix the immobilized composite enzyme particles in step 3) with fish paste, enzymolyze and stir, and the enzymolysis temperature is 40-60°C, enzymatic hydrolysis time is 2-10 hours, after enzymatic hydrolysis, sieve to separate the immobilized compound enzyme particles. The method can improve the thermostability of the protease, and the immobilized composite enzyme particles can be recycled and reused, thereby reducing the production cost. In addition, the use of immobilized composite enzyme particles for one-time enzymatic hydrolysis of fish paste has high enzymatic hydrolysis efficiency.

Description

technical field [0001] The invention belongs to the technical field of proteolysis, and in particular relates to a method for producing fish peptides by using immobilized composite protease. Background technique [0002] Fish has high protein content, complete types of essential amino acids, and has the characteristics of good composition ratio and balance. Fish peptide is not only an important nitrogen source, but also has a series of physiological functions in the body, such as lowering blood cholesterol, reducing body fat, and enhancing body immunity. [0003] There are many ways to prepare fish peptides, the main method is enzymatic hydrolysis. Fish protein enzymatic hydrolysis is the enzymatic hydrolysis of fish protein into fish peptides under the action of various proteases. However, due to the shortcomings of enzyme variability, low temperature resistance, and difficult recovery, the enzyme can be solidified and then enzymatically hydrolyzed. For example, the inve...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12N11/14C12N11/10C12N11/02C12P21/06
CPCC12N11/02C12N11/10C12N11/14C12P21/06
Inventor 劳泰财余忠丽恽辉王俊青程林春
Owner 广东希普生物科技股份有限公司