Hoof nail polypeptide tablet and preparation process thereof

A preparation process and technology of hoof nails, applied in the field of hoof nail polypeptide tablets and its preparation, can solve the problems of inability to exert the hoof hoof polypeptide function, affect the hoof hoof polypeptide effect, uneven drug mixing, etc., and achieve the improvement of endometrial blood vessels Effects of blood flow disturbance, reduction of vascular permeability, and avoidance of adverse reactions

Pending Publication Date: 2020-04-14
重庆天致药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, hoof nail peptides are mostly used in other drugs, or directly use hoof nail peptides to cooperate with other drugs to treat diseases. There is no precedent for using hoof nail polypeptides to make tablets. The current method of using hoof nail polypeptides to treat diseases It is impossible to play a better role of hoof nail polypeptide, and the existing pills or decoctions, uneven drug mixing, high loss rate, imprecise purification, etc. affect the role of hoof nail polypeptide to a certain extent

Method used

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  • Hoof nail polypeptide tablet and preparation process thereof

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Effect test

Embodiment 1

[0037] The invention provides a hoof nail polypeptide tablet and a preparation process thereof. The hoof nail polypeptide tablet consists of 35 parts of hoof nail polypeptide, 5 parts of corn starch, 15 parts of sucrose, 5 parts of carboxymethyl starch sodium, 0.2 parts of magnesium stearate, 0.5 parts of Part silicon dioxide, 8 parts of ethanol (60%) and 20 parts of ethanol (80%) are made, wherein when making coating, add 2.5 parts of pharmaceutical film coating premix.

[0038] Hoof nail polypeptide sheet preparation process such as figure 1 Shown:

[0039] Step 1, removing the outer packaging of the hoof nail polypeptide raw material;

[0040] Step 2, material preparation, prepare 35-40 parts of hoof nail polypeptide, 5-10 parts of corn starch, 15-20 parts of sucrose, 5-10 parts of carboxymethyl starch sodium, 0.2-0.4 parts of magnesium stearate, 0.5-0.8 parts of Silica, 8-12 parts of ethanol (60%) and 20-25 parts of ethanol (80%), add three quarters of water to 95% ethan...

Embodiment 2

[0057] The difference between embodiment two and embodiment one is only that the hoof nail polypeptide sheet is composed of 40 parts of hoof nail polypeptide, 10 parts of cornstarch, 20 parts of sucrose, 10 parts of carboxymethyl starch sodium, 0.4 part of magnesium stearate, 0.8 part of dioxide Silicon, 12 parts of ethanol (60%) and 25 parts of ethanol (80%), wherein 4.5 parts of pharmaceutical film coating premix are added when making the coating.

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Abstract

The invention discloses a hoof nail polypeptide tablet and a preparation process thereof. The hoof nail polypeptide tablet is prepared from 35-40 parts of hoof nail polypeptide, 5-10 parts of corn starch, 15-20 parts of cane sugar, 5-10 parts of sodium carboxymethyl starch, 0.2-0.4 part of magnesium stearate, 0.5-0.8 part of silicon dioxide, 8-12 parts of ethyl alcohol (60%) and 20-25 parts of ethyl alcohol (80%). The preparation method comprises the following steps: Step 1, removing outer packing of the hoof polypeptide raw material; Step 2, preparing materials; Step 3, crushing; Step 4, preparing materials; Step 5, granulating; and Step 6, drying and the like. The problems of nonuniform mixing, high loss rate, inaccurate purification and the like of existing pills or decoctions influencing the effect of hoof nail polypeptide to some extent are solved.

Description

technical field [0001] The invention relates to the field of medicine processing, in particular to a hoof nail polypeptide tablet and a preparation process thereof. Background technique [0002] The hoof of the pig (Susscrofa domestica Brisson) is referred to as the hoof of pigs, also known as pig hoof, pig hoof and pig zygote. Pig's trotter armor is a traditional Chinese medicinal material, which is salty in taste and non-toxic. It enters the Yangming Jing and has certain medicinal value. In "Shen Nong's Materia Medica", there is a record of the use of hoofnails as medicine. In the "Compendium of Materia Medica" of Ming Dynasty, there are "hanging hoofnails", "taste is salty and non-toxic, and it is mainly used to treat five hemorrhoids. Akagi-burning and smoke, to get rid of all evil sore gas" record. [0003] Modern pharmacological studies of traditional Chinese medicine have shown that trotter nails mainly contain chemical components such as keratin, peptides, amino ac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/28A61K47/36A61K47/26A61K47/12A61K47/04A61K38/02A61P7/04A61P9/14A61P1/00
CPCA61K9/2806A61K9/2059A61K9/2018A61K9/2013A61K9/2009A61K9/2095A61K9/2893A61K38/02A61P7/04A61P9/14A61P1/00
Inventor 刘玉琴
Owner 重庆天致药业股份有限公司
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