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United application of quercetin and antibacterials

A technology of combined application of antibacterial drugs, applied in the direction of antibacterial drugs, resistance to vector-borne diseases, medical preparations containing active ingredients, etc., can solve life-threatening health, serious bacterial resistance, long cycle and other problems, Achieve the effect of reducing dosage, enhancing antibacterial efficacy and reducing bacterial resistance

Pending Publication Date: 2020-05-05
CHINA AGRI UNIV
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Problems solved by technology

However, with the frequent and large-scale use of antimicrobials around the world, bacterial resistance is becoming more and more serious, and the emergence of "super bacteria" has become a worldwide problem, threatening life and health at all times
However, the development of new antibacterial drugs is currently costly and takes a long time, and drug combination has great potential as a solution to the problem of bacterial resistance

Method used

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  • United application of quercetin and antibacterials
  • United application of quercetin and antibacterials
  • United application of quercetin and antibacterials

Examples

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Embodiment Construction

[0024] In order to clearly illustrate the technical characteristics of this program, the following describes this program through specific implementation methods.

[0025] A combined application of quercetin and antibacterial drugs, characterized in that the combined use of quercetin and antibacterial drugs can produce synergistic antibacterial efficacy, reduce the minimum antibacterial sepsis and minimum bactericidal concentration of antibacterial drugs, and be used in the preparation of new drugs and improve antibacterial Application of drugs in clinical effect.

[0026] Described bacterium is Gram-negative bacteria, preferably, is represented by pathogenic Escherichia coli and standard Escherichia coli.

[0027] The antibacterial drug is any one of tetracycline, chlortetracycline, oxytetracycline and doxycycline;

[0028] Preferably, the antibacterial drug can also be any one of ofloxacin, norfloxacin, ciprofloxacin, florfenicol, cefquinome, and ceftiofur.

[0029] The pr...

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Abstract

The invention provides united application of quercetin and antibacterials, and belongs to the field of antibacterials. The technical scheme adopted by the invention lies in that through the united medication of the quercetin and the antibacterials, synergistic antibacterial potency can be produced, the minimum inhibitory concentration and the minimum bactericidal concentration of the antibacterials can be reduced, and the quercetin and the antibacterials can be applied to preparation of new medicines and improvement of clinical effects of the antibacterials. The united application disclosed bythe invention has the beneficial effects that the united medication of the combination of the quercetin and the antibacterials can restrain the growth of bacteria, besides, the quercetin has the effect of synergistically resisting escherichia coli with the antibacterials, the antibacterials can restrain the growth of pathogenic bacteria at lower dosage, the antibacterial potency of the antibacterials is reinforced, the production of drug resistance of bacteria can be reduced, the effect of resisting bacterium infection is improved, the usage dosage of the antibacterials is reduced, and a compound recipe or a combination can be applied to prevention and treatment of bacterial infection diseases.

Description

technical field [0001] The present invention relates to a kind of antimicrobial drug field, relate in particular to a kind of combined application of quercetin and antibacterial drug. Background technique [0002] Antimicrobials have played an important role in reducing disease and death in animals, and their discovery and application have made significant contributions to human and animal health. However, with the frequent and large-scale use of antimicrobials worldwide, bacterial resistance is becoming more and more serious, and the emergence of "super bacteria" has become a worldwide problem, threatening life and health at all times. However, the development of new antimicrobial drugs is currently costly and takes a long time, and drug combination has great potential as a solution to the problem of bacterial drug resistance. Contents of the invention [0003] The object of the present invention is to provide a kind of can inhibit bacterial growth, simultaneously querce...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61K31/65A61P31/04
CPCA61K31/352A61K31/65A61P31/04Y02A50/30
Inventor 郝智慧戴存春曲少奇王苹苹黄亭亭
Owner CHINA AGRI UNIV
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