Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition and preparation method and application thereof

The technology of a composition and traditional Chinese medicine is applied in the field of traditional Chinese medicine composition and its preparation, which can solve the problems of unsatisfactory curative effect, decreased life quality, low immunity and the like, and achieve the effects of improving body immunity, reducing cancer pain and recovering appetite.

Active Publication Date: 2020-05-29
成都菱祐生物科技有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The incidence of malignant tumors has been increasing year by year with the negative effects of social development on the environment. At present, modern medical methods for the treatment of malignant tumors are mainly surgery, drug chemotherapy and radiotherapy, but the curative effect is not satisfactory. The efficiency is only 10-20%, and the effective rate of combined chemotherapy is only about 30%-40%. After the operation and long-term chemotherapy, the tumor patients are in a state of low immunity, and the risk of suffering from the second tumor is greatly increased. , decreased quality of life
And the side effects of chemicals have appeared one by one in the process of application, and the consequences of their side effects are sometimes greater than the severity of their therapeutic effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition and preparation method and application thereof
  • Traditional Chinese medicine composition and preparation method and application thereof
  • Traditional Chinese medicine composition and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0042] The preparation method of the invention is simple, has high extraction rate of active ingredients of the medicine, remarkable curative effect, is accurate and reliable, can more comprehensively guarantee the curative effect and quality of the compound traditional Chinese medicine, is suitable for clinical popularization and application, and has good practicability. Pharmacodynamic experiments have confirmed that the traditional Chinese medicine preparation of the present invention has a significant inhibitory effect on liver cancer cell models in vivo and in vitro, and does not cause pathological damage to the liver, kidney and intestinal tract. The preparation method has the advantages of small dosage, convenient administration, and good stability. , less side effects and other advantages.

[0043] In the present invention, the traditional Chinese medicine composition can be abbreviated as AH-05.

[0044] A Chinese medicine composition provided by the present invention...

Embodiment 1

[0045] Embodiment 1: Chinese medicine composition of the present invention

[0046] 6 parts of Gentiana, 9 parts of Banzhilian, 6 parts of Sophora flavescens, 20 parts of reed root, 12 parts of Agrimony, 10 parts of mistletoe, 15 parts of Prunella vulgaris, 10 parts of Salvia miltiorrhiza, and 20 parts of Astragalus.

[0047] Preparation method: Mix the raw materials and crush them into coarse powder, then soak the coarse powder of medicinal materials with 0.5% hydrochloric acid aqueous solution at room temperature for 2 hours, and then perform ultrasonic extraction: ultrasonic time 40min / time, ultrasonic frequency 20KHz, dosing volume 8 Double the amount / time, repeat the extraction twice; extraction solvent: 0.2-1.0% hydrochloric acid aqueous solution, combine the filtrates, concentrate under reduced pressure to 2 / 3-1 / 2 volume, then adjust the pH to 10 with ammonia water, centrifuge to discard the precipitate, Then use dichloromethane to extract the supernatant (the ratio is ...

Embodiment 2

[0048] Embodiment 2: Chinese medicine composition pharmaceutical composition analysis of the present invention

[0049] The traditional Chinese medicine composition of Example 1 of the present invention is subjected to major component analysis. The analysis method is as follows:

[0050] 1. Dragendorff reagent method:

[0051] Pre-solution: 0.85g of bismuth subnitrate is dissolved in 10ml of glacial acetic acid, added with 40ml of water, dissolved, and obtained.

[0052] Take 5ml before use, add 5ml of potassium iodide solution (4→10), add 20ml of glacial acetic acid, dilute with water to 100ml, and obtain.

[0053] Detection method: take 1m1 sample of dilute acid solution and add 1-2 drops of reagent, resulting in yellow to orange turbidity or precipitation.

[0054] 2. Hager reagent method

[0055] Dissolve 1g of picric acid in 100ml of water.

[0056] Detection method: take 1ml sample neutral solution, add 1-2 drops of reagent, and produce yellow crystal precipitate. ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition is a hydrochloric acid extract of gentian, sculellaria barbata, radix sophorae flavescentis, rhizoma phragmitis, hairyvein agrimony, mistletoe, selfheal, salvia miltiorrhiza and astragalus membranaceus. The hairyvein agrimony, mistletoe, salvia miltiorrhiza and rhizoma phragmitis in the traditional Chinese medicine composition are combined to achieve the effect of directly inhibiting tumor cell growth; astragalus membranaceus and salvia miltiorrhiza are combined to benefit qi, tonify the middle warmer, strengthen body resistance and eliminate pathogenic factors;gentian has the effects of protecting liver and benefiting gallbladder. All the medicines are used together to reach the focus, so that the traditional Chinese medicine composition can protect liver and gallbladder, increase body autoimmunity, relieve fever and relieve pain and has the effects of resisting tumors and strengthening body resistance and tonifying qi.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition and its preparation method and application. Background technique [0002] The incidence of malignant tumors has been increasing year by year with the negative effects of social development on the environment. At present, modern medical methods for the treatment of malignant tumors are mainly surgery, drug chemotherapy and radiotherapy, but the curative effect is not satisfactory. The efficiency is only 10-20%, and the effective rate of combined chemotherapy is only about 30%-40%. After the operation and long-term chemotherapy, the tumor patients are in a state of low immunity, and the risk of suffering from the second tumor is greatly increased. , quality of life declines. And the side effects of chemicals have appeared one by one in the process of application, and the consequences of the side effects a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/899A61P35/00A61P1/16
CPCA61K36/185A61K36/481A61K36/489A61K36/515A61K36/536A61K36/537A61K36/539A61K36/73A61K36/899A61K2236/33A61K2236/53A61K2236/55A61P1/16A61P35/00A61K2300/00
Inventor 李显勇李燕雏陈露尹卫华阮秀娟李琪
Owner 成都菱祐生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com