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Fel ursi cooling patch and preparation method thereof

A technology of cooling paste and bear bile is applied in pharmaceutical formulations, medical preparations containing active ingredients, heating appliances for treatment and other directions, and can solve the problems of no longer cooling effect, worse cooling effect, no cooling effect, etc. , to achieve the effect of alleviating the side effects of fever, high biological safety and high production efficiency

Active Publication Date: 2020-06-19
青岛兔护士海洋生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the existing technologies and cooling stickers sold on the market still have insufficient cooling effects. It will no longer play a cooling role and needs to be replaced, and if it is replaced too frequently, it will undoubtedly increase the operational inconvenience and economic burden of patients with fever; Other symptoms also have no therapeutic and / or palliative effect to better alleviate the suffering of a febrile patient

Method used

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  • Fel ursi cooling patch and preparation method thereof
  • Fel ursi cooling patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Bear bile cooling patch of the present invention is made of the following components by weight percentage:

[0041] Carbomer 0.5%, Sodium Benzoate 0.1%, Bear Bile Powder 0.05%, Agar 12%, Distilled Water 54.5%, Glycerin 25%, Polyvinylpyrrolidone (K30) 0.6%, Carboxymethylcellulose Sodium 0.5%, Sodium Polyacrylate (NP700) 4%, aluminum glycylate 0.3%, ethylenediaminetetraacetic acid disodium (EDTA-2Na) 0.08%, borneol 0.03%, menthol 0.04%, absolute ethanol 2%, tartaric acid 0.3%;

[0042] The preparation method comprises the following steps:

[0043](1) Sodium benzoate was dissolved in distilled water (24.5%), and stirred for 60 min until uniform; carbomer was dissolved in distilled water (5%), and the swollen carbomer was added in aqueous sodium benzoate, stirred for 60 min until uniform; agar was dissolved In distilled water (10%), heat to 70°C until completely dissolved, add the agar aqueous solution to the sodium benzoate-carbomer mixed solution while hot, stir for 60 m...

Embodiment 2

[0052] Bear bile cooling patch of the present invention, the same part as embodiment 1 will not be repeated, the difference is that the consumption of the following components is adjusted to: bear bile powder 0.03%, borneol 0.04%, menthol 0.05%.

Embodiment 3

[0054] For the bear bile cooling patch of the present invention, the same parts as those in Example 1 will not be repeated, the difference is that the dosage of the following components is adjusted to: agar 10%, sodium polyacrylate (NP700) 6%.

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Abstract

The invention discloses a fel ursi cooling patch. The fel ursi cooling patch is mainly prepared from the following components by weight: 0.05%-5% of carbomer, 0%-0.5% of aseptic, 0.01%-0.1% of fel ursi powder, 0%-40% of agar, 40%-75% of water, 15%-40% of glycerol, 0%-5% of polyvinylpyrrolidone, 0%-5% of ionic cellulose gum, 1%-15% of polyacrylate, 0%-5% of aluminum glycinate, 0%-0.5% of edetate, 0%-0.5% of borneol, 0%-0.5% of menthol, 0%-5% of ethanol and 0%-5% of antioxidant. The fel ursi cooling patch provided by the invention not only can achieve effective cooling and long-acting cooling effects, but also can effectively alleviate inflammation, spasm and other symptoms that are simultaneously accompanied with fever; and the fel ursi cooling patch has high bio-safety and is suitable forbeing used by fever patients and particularly patients suffering from the fever for a long time.

Description

technical field [0001] The invention belongs to the technical field of cooling stickers, and in particular relates to a bear bile cooling sticker and a preparation method thereof. Background technique [0002] Fever is a common clinical symptom, which is usually caused by virus, bacterial infection or other diseases. It may also be accompanied by inflammation, red eyes, swelling and pain, headache, nasal congestion and other symptoms. Work is a big inconvenience. [0003] Effective ways to treat fever mainly include: oral medicine cooling and physical cooling, etc. The disadvantages of oral medicine cooling are relatively large side effects, drug resistance may develop, and the cooling effect is not good. Physical cooling methods can avoid these problems. [0004] Among the methods of physical cooling, cooling stickers have been accepted by more and more people because of their practicability and convenience. Cooling patch, also called antipyretic patch, cold compress patc...

Claims

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Application Information

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IPC IPC(8): A61K35/413A61K9/70A61P29/00A61F7/02
CPCA61K35/413A61K9/7061A61P29/00A61F7/02A61F2007/0261A61F2007/0219Y02A50/30
Inventor 李育强智倩倩孔晓颖赵璐
Owner 青岛兔护士海洋生物科技有限公司
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