Targeted slow-release nasal film-forming spray capable of forming film to inhibit viruses and bacteria and production method of targeted slow-release nasal film-forming spray capable of forming film to inhibit viruses and bacteria

Abstract

The invention relates to the field of biology, in particular to a targeted slow-release nasal film-forming spray capable of forming a film to inhibit viruses and bacteria and a production method of the targeted slow-release nasal film-forming spray capable of forming the film to inhibit the viruses and the bacteria. The purpose is to solve the problems that existing common film-forming sprays cannot inhibit or kill viruses and bacteria in a targeted way, are short in action time, cannot effectively isolate survival environments of the viruses for a long term, and are low in virus replication inhibiting efficiency. According to the targeted slow-release nasal film-forming spray capable of forming the film to inhibit the viruses and the bacteria and the production method of the targeted slow-release nasal film-forming spray capable of forming the film to inhibit the viruses and the bacteria, a layer of soluble protective film is formed by adopting PVP, and a slow-release effect of CMC-NAis used. Survival environments of the viruses and the bacteria are effectively destroyed through a physical and biological double antibacterial mechanism, and effects of fighting inflammation, inhibiting the bacteria and isolating and killing viral microorganisms (including the bacteria and the viruses) are achieved. Through a targeting agent angiotensin 2 inhibitor and EDTA2Na, double advantagesof a technology prescription, with targeted administration and slow-release administration combined, and a component mechanism are achieved. The targeted slow-release nasal film-forming spray capableof forming the film to inhibit the viruses and the bacteria and the production method of the targeted slow-release nasal film-forming spray capable of forming the film to inhibit the viruses and thebacteria are applied to the field of medicines.

Description

technical field [0001] The invention relates to the field of biology, in particular to a targeted, slow-release, film-forming nasal cavity spray agent for inhibiting viruses and bacteria and a preparation method thereof. Background technique [0002] A virus is a microorganism composed of a nucleic acid molecule (DNA or RNA) and protein, without a cell structure but with life characteristics such as heredity and replication. The characteristics of viruses are: ① small in size, with a diameter of 20-200nm, and need to be observed with the help of an electron microscope, and can pass through a bacterial filter; ② simple in structure, as a non-cellular microorganism, the virus has no cell wall, cell membrane, or even a nucleus. The substance RNA or DNA is covered with a layer of protein capsid. The functions of the capsid are: ① antigenicity; ② protecting nucleic acid; ③ mediating the combination of virus and host cells; Most of the time, it is in a dormant state. Once it enco...

AI Technical Summary

Problems solved by technology

[0006] The present invention aims to solve the problem of the existing common film-spraying agents: they cannot be targeted to inhibit and kill viruses and bacteria, the action time is short, and they cannot effectively isolate the virus living environment for a long time and inhibit Due to the problem of low virus replication efficiency, a new type of targeted, slow-release, film-forming spray film agent is formed to isolate viruses, protect mucous membranes, stick viruses so that they cannot replicate, and destroy virus survival for a long time

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