Oral antibacterial composition as well as oral care solution prepared from same and application
A technology of oral care solution and composition, which is applied in the field of medicine, can solve problems such as oral microecological imbalance, failure to prevent oral diseases, and Candida albicans infection, and achieve the effects of reducing the number, improving the oral microenvironment, and caring for health
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Embodiment 1
[0035] Embodiment 1 oral antibacterial composition formula
[0036] This example provides a series of formulations of oral antibacterial compositions, which are formed by mixing the components shown in Table 1.
[0037] Table 1
[0038] combination Lysozyme (g) FOS (g) Rice Germ Extract (g) Recipe 1 0.5 1.5 3 Recipe 2 0.5 2 5 Recipe 3 1 1.5 3 Recipe 4 0.2 1.5 1 Recipe 5 0.2 1 1 Recipe 6 0.5 2 - Recipe 7 - 2 5 Recipe 8 0.5 - 5
Embodiment 2
[0039] Embodiment 2 antibacterial composition formula antibacterial activity experiment
[0040] 1. Antibacterial test method
[0041] According to 7.3 of QB 2738-2012 "Evaluation Method for Antibacterial and Antibacterial Effects of Daily Chemical Products" as the detection basis, to detect Streptococcus mutans, Porphyromonas gingivalis, Staphylococcus aureus, Escherichia coli, Candida albicans, common The inhibition rate of bacteria etc. is an investigation index, and the bacteriostasis effect of different bacteriostatic composition formulas among the embodiment 1 is evaluated. The specific operation method is as follows:
[0042] (1) Dilute Streptococcus mutans, Porphyromonas gingivalis, Staphylococcus aureus, Escherichia coli, Candida albicans, Prevotella intermedium and other bacteria with PBS (0.03mol / L phosphate buffer) solution to concentration 1×10 4 ~9×10 4 cfu / mL;
[0043] (2) Dilute the test sample to the specified concentration with sterile standard hard water;...
Embodiment 3
[0057] Embodiment 3 oral care liquid
[0058] 1. Raw materials
[0059] The ingredients of oral care solutions with different ratios are shown in Table 3.
[0060] table 3
[0061]
[0062]
[0063] 2. Preparation method of oral care solution
[0064] S1. Preparation of water-soluble components of group A: add humectant, foaming agent, sweetener, fructooligosaccharide, rice germ extract, water, and stir for 10-50 minutes;
[0065] S2. Preparation of oil-soluble components in group B: add solubilizer and essence, and stir for 10-50 minutes;
[0066] S3. Add group B to group A, stir for 10-50 minutes to obtain AB mixture;
[0067] S4. Add lysozyme into the fully mixed AB mixture, and stir for 10-50 minutes to obtain oral care solutions 1-9.
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