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Traditional Chinese medicine composition with anti-inflammatory and repairing effects and preparation method

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and preparation with anti-inflammatory and repairing effects, can solve the problems of waste and ineffective use of functional components of mulberry seeds, etc., to improve the use effect, promote skin metabolism, resist skin irritating effects

Inactive Publication Date: 2020-11-20
SHANGHAI JAKA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Mulberry seeds, the seeds of mulberry, are distributed on the surface of mulberry fruit. Because mulberry seeds are by-products left after mulberry processing, they are only used in feed at present, and mulberry seeds contain a large number of functional components that have not been effectively utilized, resulting in a great waste

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0051] S1: Prepare materials;

[0052] S2: Preparation of mulberry seed extract A and additives:

[0053] Take mulberry seeds, wash and dry, shear and pulverize, pass through a 40-mesh sieve, then place in n-hexane, extract in a water bath at 60°C for 3 hours, and filter to obtain filtrate and filter residue;

[0054] Take the filter residue, place it in 70% ethanol solution, extract it in a water bath at 45°C for 40 minutes, and filter it with suction to obtain the mulberry seed extract A;

[0055] Take the filtrate, add phosphoric acid, mix and stir at 40°C for 30 minutes, let stand for 6 hours, continue to filter, neutralize and remove acid, and obtain mulberry seed extract B; take mulberry seed extract B, add N,N-dimethyl-1, 3-Propanediamine, reacted at 160°C for 4 hours, removed N,N-dimethyl-1,3-propanediamine by rotary evaporation, then added the first solvent, and reacted under reflux for 3 hours to obtain material C;

[0056] Take material C, add potassium hydroxide ...

example 2

[0065] S1: Prepare materials;

[0066] S2: Preparation of mulberry seed extract A and additives:

[0067] Take mulberry seeds, wash and dry, shear and pulverize, pass through a 40-mesh sieve, then place in n-hexane, extract in a water bath at 63°C for 3.5 hours, and filter to obtain the filtrate and filter residue;

[0068] Take the filter residue, place it in 70% ethanol solution, extract it in a water bath at 46°C for 45 minutes, and filter it with suction to obtain the mulberry seed extract A;

[0069] Take the filtrate, add phosphoric acid, mix and stir at 42°C for 35 minutes, let stand for 6.5 hours, continue to filter, neutralize and remove acid, and obtain mulberry seed extract B; take mulberry seed extract B, add N,N-dimethyl-1 , 3-propanediamine, reacted at 162°C for 4.5 hours, removed N,N-dimethyl-1,3-propanediamine by rotary evaporation, then added the first solvent, and refluxed for 3.5 hours to obtain material C;

[0070] Take material C, add potassium hydroxide...

example 3

[0079] S1: Prepare materials;

[0080] S2: Preparation of mulberry seed extract A and additives:

[0081] Take mulberry seeds, wash and dry, shear and pulverize, pass through a 40-mesh sieve, then place in n-hexane, extract in a water bath at 65°C for 4 hours, and filter to obtain filtrate and filter residue;

[0082] Take the filter residue, place it in 70% ethanol solution, extract it in a water bath at 48°C for 50 minutes, and filter it with suction to obtain the mulberry seed extract A;

[0083] Take the filtrate, add phosphoric acid, mix and stir at 45°C for 40 minutes, let stand for 7 hours, continue to filter, neutralize and remove acid, and obtain mulberry seed extract B; take mulberry seed extract B, add N,N-dimethyl-1, 3-Propanediamine was reacted at 165°C for 5 hours, and N,N-dimethyl-1,3-propanediamine was removed by rotary evaporation, then the first solvent was added, and the reaction was refluxed for 4 hours to obtain material C;

[0084] Take material C, add po...

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Abstract

The invention discloses a traditional Chinese medicine composition with anti-inflammatory and repairing effects and a preparation method. The method comprises the following steps: treating additives,and regulating ph value with stirring, so that oleamidopropyl betaine and conjugated linoleic acid in the additives react under the condition to form sustained-release vesicles at room temperature; and then adding a prepared mulberry seed extracting solution A, a mixed extracting solution, a bitter gourd extracting solution and a calyx seu fructus physalis extracting solution immediately, and coating the components in the extracting solutions by using the sustained-release vesicles so as to obtain the traditional Chinese medicine composition. The prepared traditional Chinese medicine composition not only has a medicine slow release function, the stability of the traditional Chinese medicine composition is improved, the use effect of the traditional Chinese medicine composition is improved,meanwhile, the adopted traditional Chinese medicinal materials are all pure traditional Chinese medicinal materials, and the traditional Chinese medicinal composition has the functions of resisting aging, preserving moisture, promoting skin metabolism, resisting bacteria, diminishing inflammation and the like, and can be used for skin surface care, eczema treatment and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with anti-inflammatory and repairing effects and a preparation method. Background technique [0002] Mulberry, also known as mulberry and mulberry, is one of the precious medicinal and edible fruits. Mulberry is the fruit of the mulberry tree of the family Morusaceae. Many people in our country like its ripe fruit—red and white, with plump flesh and rich juice. Medical experts believe that mulberry tastes slightly sour and cold, and has the effects of enhancing the body's immune effect, preventing anemia, quenching thirst, and moisturizing the intestines. Therefore, mulberry has been generally considered by people to be a class of food that has both nutritional supplements and health care effects. There are more and more green and diverse foods and Chinese herbal medicine powders created with mulberries as raw mate...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P29/00A61P17/00
CPCA61K36/39A61K36/42A61K36/43A61K36/45A61K36/484A61K36/489A61K36/539A61K36/605A61K36/81A61K36/9066A61K2236/15A61K2236/17A61K2236/19A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P17/00A61P29/00A61K2300/00
Inventor 田军卢伊娜
Owner SHANGHAI JAKA BIOTECH CO LTD
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