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Radix Rehmanniae Recens extraction method, Radix Rehmanniae Recens extracting solution, fresh rehmannia root particles and composition

An extraction method, the technology of fresh rehmannia, is applied in the direction of medical formula, plant raw materials, wave energy or particle radiation treatment materials, etc. It can solve the problems that hinder the development of fresh medicine preparations, microorganisms are easily unqualified, and affect the curative effect of diseases, etc., and achieve high industrial efficiency. Application value, reduction of food risk, comprehensive effect of active ingredients

Inactive Publication Date: 2020-12-01
GUANGDONG YIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are large differences between raw rehmannia and fresh rehmannia in terms of chemical composition, pharmacological effects, usage and dosage, etc., which will inevitably affect its curative effect on certain diseases.
[0004] In the modern technology, there is a kind of traditional Chinese medicine fresh rehmannia slices and its processing technology. The method is to quickly dry the fresh rehmannia slices at a temperature below 100°C. This method solves the preservation problem of fresh rehmannia to a certain extent, but after 4 to 12 hours The roasting and dehydration drying of fresh rehmannia glutinosa is basically the same as the raw rehmannia glutinosa process of slowly roasting to about 80% dry, which has lost the "fresh use" characteristics of fresh rehmannia glutinosa, resulting in the inactivation of some active components and a decrease in medicinal value
Although the traditional Chinese medicine decoction method can be used to retain the "fresh" characteristics of fresh medicine, the extraction efficiency of this method is low, the functional components are single, and there is a serious problem in fresh medicine preparations that microorganisms are easily unqualified. And this problem is also one of the important problems hindering the development of fresh medicine preparations

Method used

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  • Radix Rehmanniae Recens extraction method, Radix Rehmanniae Recens extracting solution, fresh rehmannia root particles and composition
  • Radix Rehmanniae Recens extraction method, Radix Rehmanniae Recens extracting solution, fresh rehmannia root particles and composition
  • Radix Rehmanniae Recens extraction method, Radix Rehmanniae Recens extracting solution, fresh rehmannia root particles and composition

Examples

Experimental program
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Effect test

preparation example Construction

[0059]The present invention also provides a method for preparing fresh Dihuang granules, including the following steps:

[0060]S201: Provide fresh rehmannia glutinosa extract;

[0061]The extraction method of the fresh rehmannia glutinosa extract is as described in steps S101-S105, and will not be repeated here.

[0062]S202: Concentrate, dry, and granulate the fresh Rehmannia glutinosa extract.

[0063]Among them, the drying method can be a method commonly used in the art, which is not particularly limited here, including but not limited to: freeze drying, spray drying, belt drying, vacuum drying, and air-blast drying. use. The granulation method can be granulated by granulating equipment commonly used in the art.

Embodiment 1

[0066]The preparation method of fresh Dihuang granules includes the following steps:

[0067]a. Remove the reeds, fibrous roots and silt from the harvested fresh rehmannia glutinosa, wash and drain the surface water; spread the fresh rehmannia glutinosa after draining the surface water on a clean platform, and place it under ultraviolet light. Bacterium 1h;

[0068]b. Crush the sterilized fresh Rehmannia glutinosa into pieces with a coarse crusher, put it into a homogenizer, add 3 times the amount of water, and homogenize at 5°C for 30 minutes, and filter to obtain fresh rehmannia glutinosa homogenate juice and medicine residue;

[0069]c. Take the fresh rehmannia glutinosa homogenate juice and sterilize it in an ultra-high temperature instantaneous sterilizer at 100~200℃ for 30 seconds to obtain the first concoction, and then concentrate the first concoction at 40~65℃ under reduced pressure. The relative density is 1.02, and the first concentrated medicinal juice is obtained;

[0070]d. Take t...

Embodiment 2

[0073]The preparation method of fresh Dihuang granules includes the following steps:

[0074]a. Remove the reeds, fibrous roots and silt from the harvested fresh rehmannia glutinosa, wash and drain the surface water; spread the fresh rehmannia glutinosa after draining the surface water on a clean platform, and place it under ultraviolet light. Bacterium 1h;

[0075]b. Crush the sterilized fresh Rehmannia glutinosa into pieces with a coarse crusher, put it into a homogenizer, add 3 times the amount of water, and homogenize at 5°C for 30 minutes, and filter to obtain fresh rehmannia glutinosa homogenate juice and medicine residue;

[0076]c. Take the fresh rehmannia glutinosa homogenate juice and sterilize it in an ultra-high temperature instant sterilizer at 100~200℃ for 30 seconds to obtain the first concoction, and then concentrate the first concoction at 40~65℃ under reduced pressure. The relative density is 1.02, and the first concentrated medicinal juice is obtained;

[0077]d. Take fresh R...

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Abstract

The invention provides a Radix Rehmanniae Recens extraction method, a Radix Rehmanniae Recens extracting solution, Radix Rehmanniae Recens particles and a composition. The Radix Rehmanniae Recens extraction method comprises the following steps: taking Radix Rehmanniae Recens plants for ultraviolet sterilization; crushing and homogenizing the Radix Rehmanniae Recens subjected to ultraviolet sterilization to obtain juice and medicine residues; carrying out ultrahigh-temperature instantaneous sterilization on the juice to obtain first medicine juice; decocting medicine residues to obtain second medicine juice; and combining the first medicine juice and the second medicine juice to prepare the Radix Rehmanniae Recens extracting solution. According to the Radix Rehmanniae Recens extraction method, a Radix Rehmanniae Recens preparation with high microorganism percent of pass and comprehensive functional components can be obtained.

Description

Technical field[0001]The invention relates to the technical field of traditional Chinese medicine extraction, in particular to a fresh rehmannia glutinosa extraction method, a fresh rehmannia glutinosa extract, a fresh rehmannia glutinosa granule and a composition.Background technique[0002]Fresh Rehmannia glutinosa is the fresh root of Rehmannia glutinosa Libosch. It is sweet, bitter, and cold in nature. It has the effects of clearing heat and promoting fluid, cooling blood, and hemostasis. It is used for heat disease, yin, crimson tongue, polydipsia, and poisonous hair. Spots, vomiting blood, epistaxis, throat swelling and sore throat, are fresh medicinal materials commonly used in traditional Chinese medicine, and have been used in my country for more than 2,000 years. The Lily Rehmannia Decoction contained in "The Synopsis of the Golden Chamber" is composed of lily and fresh rehmanniae juice to treat lily disease without vomiting and sweating, and the shape of the disease remains...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K41/17A61K9/16A61L2/04A61L2/10A61K125/00
CPCA61K9/16A61K36/804A61K2236/31A61K2236/331A61K2236/53A61L2/0023A61L2/0047A61L2202/21
Inventor 张志鹏鲁云徐杰田清清魏梅孙冬梅程学仁
Owner GUANGDONG YIFANG PHARMA
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