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Cosmetic preservative system

A technology of preservatives and cosmetics, which is applied in the field of new preservative systems, can solve the problems of lack of protection against it, unsafe products, and few cosmetic products of Enterobacter persicae, to achieve bacterial adaptability and resistance Reduced sexual problems, prevention of allergic or irritating effects, well tolerated effects

Pending Publication Date: 2021-01-01
BOOTS PURE DRUG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Without an effective preservative system, cosmetic products that are susceptible to the growth and multiplication of Enterobacter vulgaris may quickly receive little or no protection against it, rendering the product unsafe for human use

Method used

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  • Cosmetic preservative system
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  • Cosmetic preservative system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0192] Formulation Example 1——skin care cream

[0193]

[0194]

[0195] Production method:

[0196] 1. Add tetrasodium EDTA to water and let it dissolve.

[0197] 2. Using homogenization, distribute the carbomer and continue homogenizing for 5 minutes or until hydrated.

[0198] 3. Add methylparaben and ethylparaben, heat up to 70-75°C.

[0199] 4. Weigh out the oil phase in a separate container and heat to 70-75°C. (Caprylic / capric triglyceride, cetearyl alcohol, glyceryl stearate, cetyl alcohol, PEG-100 stearate, dimethicone, PEG-20 stearate, and Flavonyl Palmitate)

[0200] 5. When both phases are at 70-75°C, add the oil phase to the water phase and homogenize for 2 minutes.

[0201] 6. Add potassium hydroxide and homogenize for 2 minutes.

[0202] 7. Cool to room temperature.

[0203] 8. Add the phenoxyethanol and chlorhexidine digluconate while stirring.

[0204] 9. Dissolve ascorbyl glucoside in 2% water, neutralize with potassium hydroxide and stir to f...

Embodiment 2

[0210] Formulation Example 2——SPF skin care cream

[0211] Material %w / w C12-15 Alkyl Benzoate 5 Butylmethoxydibenzoylmethane 3 Ethylhexyl Methoxycinnamate 5 cetearyl alcohol 2 Ethylhexylglycerin 0.15 Glyceryl Stearate 2 cetyl alcohol 2 PEG-100 stearate 2 Polydimethylsiloxane 1.5 PEG-20 stearate 0.5 Phenoxyethanol 0.4 carbomer 0.2 Methylparaben 0.2 Ethyl p-hydroxybenzoate 0.15 Potassium hydroxide 0.06 denatured ethanol 0.5 Chlorhexidine digluconate 0.075 Tetrasodium EDTA 0.05 water to 100

Embodiment 3

[0212] Formulation Example 3 - Gel

[0213]

[0214]

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PUM

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Abstract

According to the present invention, there is provided a cosmetic composition comprising a cosmetically acceptable carrier and a preservative system, wherein the preservative system comprises (i) an antimicrobial agent; (ii) a chelating agent comprising ethylenediamine tetraacetic acid (EDTA) or a derivative thereof; and (iii) an antimicrobial booster agent selected from the group consisting of ethylhexylglycerin, caprylyl glycol, hydroxy acetophenone, caprylhydroxamic acid, phenethyl alcohol, p -anisic acid, glyceryl caprylate, levulinic acid, sodium levulinate, propanediol, hexanediol, pentylene glycol, capryloyl glycine, methylpropanediol, phenylpropanol, sodium anisate, and combinations thereof, and the antimicrobial agent is present in an amount of from about 0.001% to about 1% by weight of the composition.

Description

technical field [0001] The present invention relates to novel preservative systems and the use of these systems in cosmetics. Background technique [0002] Microbial contamination of cosmetic products is a problem and is a major cause of product recalls and financial loss to the industry. Cosmetic products are ideal substrates for the survival and development of various microorganisms as they possess water and many nutrients that promote their growth 1 . [0003] The presence of certain microorganisms in cosmetic products poses a health risk to consumers, for example, in the form of skin irritation, allergic contact dermatitis and infections, especially in the eyes, mouth or wounds. Furthermore, the presence of microorganisms may negatively affect sensory properties, eg, odor, viscosity and color of cosmetic products. [0004] The use of preservatives capable of reducing the microbial load to acceptable levels improves the microbiological quality of cosmetic products. Re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/41A61K8/34A61K8/35A61K8/40A61K8/368A61K8/37A61K8/36A61K8/44A61K8/43A61Q19/00
CPCA61K8/34A61K8/345A61K8/35A61K8/36A61K8/368A61K8/37A61K8/375A61K8/40A61K8/41A61K8/418A61K8/43A61K8/44A61K2800/51A61K2800/524A61K2800/592A61Q19/00Y02A50/30A61K8/33A61K8/342A61K8/42A61K8/498A61K2800/10A61K2800/5922
Inventor 保罗·詹姆斯·汤姆林森马克·约翰逊杰克·托马斯·希克斯
Owner BOOTS PURE DRUG CO LTD
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