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Compound lysine hydrochloride and zinc gluconate orally disintegrating tablet

The technology of oral disintegrating tablets and lysine glucosamine, which is applied in the field of pharmaceutical preparations, can solve the problems of inconvenience and stability in taking, unstable storage, unstable tablets, etc. Simple to use effect

Active Publication Date: 2021-02-09
DISHA PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Purpose of the invention: In view of the inconvenience and stability problems of the current Zinc Lysine Tablets, the purpose of this invention is to provide an orally disintegrating Zinc Lysine Tablet and solve the problem of unstable storage
[0008] The test found that adding a certain amount of sodium lauryl sulfate and fumaric acid to the prescription can solve the problem of tablet instability in high-temperature and high-humidity environments

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1. Lysine hydrochloride 40g, zinc gluconate 35g, sodium lauryl sulfate 2g, fumaric acid 4g, mannitol (granulated) 73g, sucrose 4g, croscarmellose sodium 40g, hard Magnesium fatty acid 2g. Prepare 1000 tablets according to the preparation method described in the technical scheme of the manual, and pack them in aluminum and plastic.

Embodiment 2

[0028] Example 2. Lysine hydrochloride 40g, zinc gluconate 35g, sodium lauryl sulfate 3g, fumaric acid 5g, mannitol (granulated) 71g, sucrose 4g, croscarmellose sodium 40g, Magnesium stearate 2g. Prepare 1000 tablets according to the preparation method described in the technical scheme of the manual, and pack them in aluminum and plastic.

Embodiment 3

[0029] Example 3. Lysine hydrochloride 40g, zinc gluconate 35g, sodium lauryl sulfate 4g, fumaric acid 6g, mannitol (granulated) 69g, sucrose 4g, croscarmellose sodium 40g, hard Magnesium fatty acid 2g. Prepare 1000 tablets according to the preparation method described in the technical scheme of the manual, and pack them in aluminum and plastic.

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PUM

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Abstract

The invention relates to a compound lysine hydrochloride and zinc gluconate orally disintegrating tablet, and belongs to the technical field of pharmaceutical preparations. The compound lysine hydrochloride and zinc gluconate orally disintegrating tablet contains 40 g of lysine hydrochloride, 35 g of zinc gluconate, 2-4 g of sodium dodecyl sulfate, 4-6 g of fumaric acid, 69-73 g of mannitol (granulated), 4 g of sucrose, 40 g of croscarmellose sodium and 2 g of magnesium stearate. The invention provides the stable compound lysine hydrochloride and zinc gluconate orally disintegrating tablet.

Description

technical field [0001] The invention relates to an orally disintegrating tablet of zinc lysine and belongs to the technical field of pharmaceutical preparations. Background technique [0002] Zinc Lysine is used to prevent and treat diseases caused by lysine and zinc deficiency. Most of the commercially available zinc lysine dosage forms are granules, and there are also dosage forms such as oral tablets, oral liquid preparations, and soft capsules. [0003] Lysine is an amino acid that the human body needs and cannot synthesize by itself. It can be made into hydrochloride and added to the prescription to make the required dosage form. Lysine hydrochloride is easily soluble in water, slightly soluble in alcohol, and insoluble in ether. The main function is to promote growth, enhance physical fitness, increase appetite, improve malnutrition, improve insomnia, and improve memory. Help produce antibodies, hormones and enzymes, improve the body's immunity. It can also promote...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/315A61K31/198A61K9/20A61K47/38A61K47/26A61K47/20A61K47/12A61P3/02
CPCA61K9/0056A61K9/2013A61K9/2018A61K9/2054A61K31/198A61K33/30A61P3/02A61K2300/00
Inventor 胡月杨德斌李洋张孟
Owner DISHA PHARMA GRP