56results about How to "Less gut residue" patented technology

The invention discloses a zinc gluconate orally disintegrating tablet for prevention and treatment of developmental retardation, undernourishment, apocleisis, ulcerative stomatitis, and skin acne, and its preparation. The tablet is prepared by using zinc gluconate as raw material, using bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, using bonding agent or dressing material based on specific situation, or charging right amount of effervescent agent, then using specific preparing procedure and employing a tablet compressing machine for pelleting. The tablet can be taken under the condition of waterless, it has the advantages of fast effect, improved compliance for the patients, and increased curative effect of the medicament.

An orally-disintegrating tablet of omeprazole and its derivative is prepared from omeprazole and its derivative, coating, filler, disintegrant, flavouring, flowing aid, lubricant and optional plasticizer. Its preparing process is also disclosed.

The invention discloses vonoprazan fumarate dispersible tablets, used for treating gastric and duodenal ulcers. The vonoprazan fumarate dispersible tablets are prepared from vonoprazan fumarate, with the addition of adjuvant materials. The vonoprazan fumarate dispersible tablets are rapid in disintegration and absorption, high in bioavailability, convenient to take, low in content of intestinal residues, light in side effects, sweet in taste and fragrant; and especially, the dispersible tablets are easy to improve the medication compliance of patients.

The invention discloses a sodium ferulate orally disintegrating tablet and its preparation, wherein the tablet is prepared by using sodium ferulate as raw material, using bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, using bonding agent or dressing material based on specific situation, or charging right amount of effervescent agent, then using specific preparing procedure and employing a tablet compressing machine for pelleting. The invention realizes quick disintegrating speed, good taste, the tablet can be taken under the condition of waterless, it has the advantages of fast effect, improved compliance for the patients, and increased curative effect of the medicament.

The invention discloses a domperidone orally disintergrating tablet and the preparation method. The domperidone orally disintergrating tablet of the invention contains effective dose of domperidone and pharmaceutical excipient which is capable of rapidly disintegrating and releasing medicine in the oral cavity. The preparation method adopts modern preparation technology and the product has stable quality. So the preparation method provides patients with a safe and effective domperidone orally disintergrating tablet which is absorbed rapidly.

The invention relates to hair-beautifying food for cat pets and a preparation method thereof. The food comprises the following components in part by weight: 3 to 8.7 parts of vitamin, 0.012 to 0.046 part of trace element, 0.15 to 0.5 part of unsaturated acid, 45 to 80 parts of starch, 15 to 40 parts of sucrose, 1 to 4 parts of flavoring, 2 to 6 parts of additive and 3 to 8 parts of bread yeast. The preparation method comprises the following steps of: mixing and screening a base material and other compositions respectively; puffing and molding the base material; and finally spraying a coating mixture on the base material, and performing tests to obtain a finished product. The hair-beautifying food for cat pets can be widely used for feeding the cats of different ages, can be used with other cat food together, makes the cats have healthy skins and smooth and luster hair, and has the effects of beautifying hair and features.

The invention discloses an azithromycin composition freeze-dried orally disintegrating tablet and a preparation method thereof, relates to the technical field of medicines and preparation methods thereof, and mainly solves the problems that the production process and the azithromycin preparation components are complicated, and the disintegrating tablet is low in disintegrating speed in the prior art. The azithromycin composition freeze-dried orally disintegrating tablet comprises the following components in percentage by weight: 10 to 24 percent of azithromycin, 24 to 50 percent of mannitol, 2 to 4 percent of gelatin, 32 to 74 percent of middle-substitution-degree hydroxypropyl-beta-cyclodextrin, 0.1 to 0.2 percent of sucralose and 50 percent of purified water. The preparation process of the azithromycin composition freeze-dried orally disintegrating tablet prepared by the components is simple, and the components are simple; and the azithromycin preparation can reduce the side effect of azithromycin, is convenient to take and tastes good.

The invention discloses an ethanesulfonic acid nintedanib dispersible tablet used for treating idiopathic pulmonary fibrosis (IPF). Ethanesulfonic acid nintedanib serves as the raw material, auxiliary materials are added, and the ethanesulfonic acid nintedanib dispersible tablet is prepared. The ethanesulfonic acid nintedanib dispersible tablet is rapid to disintegrate and absorb, high in bioavailability, convenient to take, less in intestinal tract residue, few in side effect and sweet in taste and has fragrance, medicine taking compliance of patients is particularly easy to improve, the taste of the preparation is improved, the sticking phenomenon cannot occur in the tabletting process, and industrial production is promoted.

The invention relates to a calcium gluconate orally disintegrating tablet which is prepared by using calcium gluconate as raw material, using bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, and using bonding agent clothing sheet material as required, or adding right amount of effervescent agent. The preparing process employs a tablet compressing machine for pelleting.

The invention relates to a wilsonii oral disintegrating tablet and its preparation process, wherein the tablet has the functions of enlivening the spleen, tonifying kidney and tranquillizing the mind, the preparation employs wilsonii extract as the raw material, and bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, bonding agent or dressing material can also be employed based on specific situation.

The invention discloses a meloxicam orally disintegrating tablet, which is of reasonable formula and good vioavailability, and the preparation method. The content of the principal agent of the meloxicam orally disintegrating tablet, meloxicam, is 5 to 20 percent. The excipient contains disintegrant, diluent or binder, adhesive, sweetener, arom atic agent, lubricant, etc. The preparation method adopts modern preparation technology and the product has stable quality. So the preparation method provides patients with safe and effective meloxicam orally disintegrating tablet.

The invention discloses pediatric compound anisodamine hydrobromide and chlorpheniramine maleate freeze-dried orally disintegrating tablets and a manufacturing method of the pediatric compound anisodamine hydrobromide and chlorpheniramine maleate freeze-dried orally disintegrating tablets, relating to the technical field of pharmaceuticals and pharmaceuticals manufacturing methods. The pediatric compound anisodamine hydrobromide and chlorpheniramine maleate freeze-dried orally disintegrating tablets comprise the following components by weight: 1.47-2% anisodamine hydrobromide, 0.14-0.2% chlorpheniramine maleate, 64-90% mannitol, 6-10% gelatin and 0.2-0.3% sucralose. The manufacturing method adopts the above components to manufacture the pediatric compound anisodamine hydrobromide and chlorpheniramine maleate freeze-dried orally disintegrating tablets. The freeze-dried orally disintegrating tablets have simple components, need no water for administration, do not need to be chewed, havea disintegration time of less than 2 minutes in an oral cavity of a human body, have the advantages of rapid absorption, high bioavailability, low intestinal tract residues, low hepatic first pass effect, less side effects and good mouthfeel, and are especially suitable for infant patients.

The invention relates to a pet food that is a cat food supplementing trace elements. The pet food comprises following components by weight: 3-10 parts of magnesium sulfate, 1-2 parts of ferrous sulphate, 0.1-0.5 part of copper sulphate, 0.05-0.3 part of manganese sulfate, 1-4 parts of zinc sulfate, 0.2-0.8 part of calcium iodate, 0.1-0.3 part of sodium selenite, 20-50 parts of starch, 10-40 parts of cane sugar, 5-20 parts of a flavoring agent, 0.5-2 parts of taurine, 5-15 parts of fish bone meal and 10-40 parts of baker's yeast powder. The pet food supplements the trace element components which domestic cats lack, improves absorption of the trace elements, and is characterized by good taste, high bioavailability, simple production equipment, easy operation and low cost. The pet food overcomes the disadvantages of common trace element preparations used for cats, namely inadequacy absorption, bad taste, and the like. According to the pet food, a manner of producing the cat food supplementing the trace elements by utilization of a common pet food production puffing technology in China is developed, is a major breakthrough for the pet food processing technology in China, makes up for blanks in the pet market in China, and takes the lead in the pet food processing technology in Tianjin and surrounding areas.

The invention discloses celecoxib effervescent tablets which are used for treating rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. The tablets can also be used for treating acute pain, dysmenorrhea, colorectal polyps and post-operative analgesia, lower back pain, shoulder periarthritis and tenosynovitis. According to the invention, celecoxib is adopted as a raw material, and auxiliary materials are added, such that the celecoxib effervescent tablets are prepared. The celecoxib effervescent tablets have the advantages of fast disintegration, fast absorption high bioavailability, convenient application, low intestinal residue, low side effect, and sweet taste and good fragrance. With the tablets and the method, patient medication compliance can easily be improved.

The invention relates to a doxycycline hydrochloride oral disintegrating tablet for domestic fowls and a preparation method thereof, wherein the composing components of the oral disintegrating tablet and the parts by weight thereof are respectively that 30-150 parts of doxycycline hydrochloride, 60-150 parts of microcrystalline cellulose, 25-60 parts of low-substituted hydroxypropyl cellulose, 50-120 parts of lactose, 30-100 parts of esibatan, 10-30 parts of milk king essence, 0.3-1 parts of saccharin sodium, and 1-3 parts of magnesium stearate. The oral disintegrating tablet has the advantages that manufacturing devices are simple, the operation is easy, the weight difference is small, and the cost is low, and breaks the conventional rule of just using freeze-dry technology to produce oral disintegrating tablets, opens up the technology for producing the oral disintegrating tablet just through adopting common powder type granule tablets in China, is an important breakthrough of the processing technology of preparations for oral use in China, and opens new possibilities in emergency treatment of animal drug markets in China.

The invention provides a pet cat food with an effect of beautifying the hair quality and hair color of a persian cat. The pet cat food is prepared from the following components in parts by weight: 3-8 parts of multi-vitamins, 3-6 parts of microelements, 55-150 parts of carbohydrate, 10-35 parts of animal protein, 15-55 parts of vegetable protein, 2-6 parts of an additive, 1-4 parts of a flavoring agent and 5-15 parts of a Chinese herbal medicine extract. The invention aims at providing the pet cat food with the effect of beautifying the hair quality and hair color of the persian cat, which is fast in absorption, high in bioavailability, few in intestinal residues and small in side effect.

The invention relates to a pet food calcium-supplement cat food and a preparation method thereof. The pet food calcium-supplement cat food comprises the following components in parts by weight: 28-40 parts of calcium-containing additive, 0.0018-0.006 part of vitamin, 18-50 parts of cane sugar, 7-15 parts of flavoring agent, 5-20 parts of starch, 0.5-2 parts of taurine and 10-40 parts of bread yeast powder. The main preparation method comprises the following steps: respectively mixing base stock and the vitamin, as well as the calcium-containing additive and the vitamin; shaping the base stock, carrying out spraying, drying and detecting and the like to prepare into finished product. The calcium-supplement cat food in the invention is chewed in an oral cavity, and is evenly distributed in a stomach; 10% of drug stays in the stomach for 5.5h; the drug has the characteristics of less residual in an intestinal tract, low side effect and high bioavailability, can effectively avoid gastric acid corrosion drug, is beneficial for improving the stability of the drug, can be widely used for cats in different ages, and also can be simultaneously used together with other cat food.

The present invention discloses an azithromycin orally disintegrating tablet and preparation method. The azithromycin orally disintegrating tablet of the present invention is composed of main medicine, excipients and coating materials, the preparation method adopts the modern preparation technology, the quality of the product is stable, and the invention can provide the azithromycin orally disintegrating tablet which is safe, effective, fast in absorption and high in bioavailability to broad patients.

The invention relates to an amoxicillin oral disintegrating tablet for domestic fowls and a preparation method thereof, wherein the composing components of the amoxicillin oral disintegrating tablet and the parts by weight thereof are respectively that 300-800 parts of amoxicillin, 100-150 parts of clavulanate potassium, 140-200 parts of microcrystalline cellulose, 20-60 parts of low-substituted hydroxypropyl cellulose, 60-120 parts of lactose, 30-80 parts of esibatan, 10-50 parts of milk king essence, 0.5-1.5 parts of saccharin sodium, and 1.5-5 parts of magnesium stearate. The amoxicillin oral disintegrating tablet has the advantages that manufacturing devices are simple, the operation is easy, the weight difference is small, and the cost is low, and breaks the conventional rule of just using freeze-dry technology to produce oral disintegrating tablets, opens up the technology for producing the oral disintegrating tablet just through adopting common powder type granule tablets in China, is an important breakthrough of the processing technology of preparations for oral use in China, and opens new possibilities in emergency treatment of animal drug markets in China.

The invention discloses freeze-dried orally disintegrating tablets of a pediatric ribavirin composition, and a preparation method thereof, and relates to the technical fields of a drug and a drug preparation method. The pediatric ribavirin composition comprises the following components, by weight, 6.0-16.32% of ribavirin, 81.62-90.01% of mannitol, 1.96-3.84% of gelatin, and 0.09-0.14% of sucralose. The invention further discloses freeze-dried orally disintegrating tablets of the pediatric ribavirin composition, and a preparation method thereof, wherein the pediatric ribavirin composition is prepared from the components. The freeze-dried orally disintegrating tablets have the following characteristics that: the components are simple; no water is required during taking; no chewing is required; the disintegrating time in the human oral cavity is less than 2 seconds; the absorption is rapid; the biological availability is high; the residue in the intestinal tract is less; the side effect is low; the liver first pass effect is low; the taste is good; and the tablets are especially suitable for infant patient taking.

The invention relates to a hair beautifying pet food for dogs and a preparation method thereof. The pet food comprises the following components in parts by weight: 3-8.06 parts of vitamin, 0.012-0.046 part of trace element, 2-6 parts of unsaturated acid, 30-70 parts of starch, 15-40 parts of cane sugar, 1-4 parts of flavoring agent, 2-6 parts of additive agent and 3-8 parts of bread yeast powder.The preparation method comprises the following main steps of: respectively mixing and screening base materials and other compositions; then puffing and molding the base materials; and finally, spraying an external coating mixture on the base materials and obtaining a finished product through inspections. After the dog food is chewed in the oral cavity, the dog food can be uniformly distributed inthe stomach, and 10 percent of the product can be detained for 5.5 hours in the stomach. The pet food has the characteristics of less intestinal residue, low side effect, quick absorption, high bioavailability, and the like, can effectively avoid gastric acid from corroding medicaments and is beneficial to increasing the stability of the medicaments.

The invention relates to a doxycycline hydrochloride orally disintegrating tablet for livestock and poultry and a preparation method thereof. 150 parts, 25-60 parts of low-substituted hydroxypropyl cellulose, 50-120 parts of lactose, 30-100 parts of aspartame, 10-30 parts of fresh milk king essence, 0.3-1 part of sodium saccharin, magnesium stearate 1-3 servings. The present invention has simple production equipment, easy operation, small weight difference, and low cost, breaks the routine of producing orally disintegrating tablets only by freeze-drying process, and opens up the domestic production of orally disintegrating tablets by adopting general powder granule compression technology, It is a major breakthrough in domestic oral preparation processing technology, and it has opened up a new way for the domestic veterinary drug market to treat emergencies.

The invention relates to a pet food supplementing trace elements for dogs and a preparing method thereof. The pet food comprises following components by weight: 3-10 parts of magnesium sulfate, 1-2 parts of ferrous sulphate, 0.1-0.5 part of copper sulphate, 0.05-0.3 part of manganese sulfate, 1-4 parts of zinc sulfate, 0.2-0.8 part of calcium iodate, 0.1-0.3 part of sodium selenite, 20-50 parts of starch, 30-70 parts of cane sugar, 1-5 parts of a flavoring agent, and 3-7 parts of pig bone meal. The pet food supplements the trace element components which domestic dogs lack, improves absorption of the trace elements, and is characterized by good taste, high bioavailability, simple production equipment, easy operation and low cost. The pet food overcomes the disadvantages of common trace element preparations used for dogs, namely inadequacy absorption, bad taste, and the like. According to the pet food and the preparing method thereof, a manner of producing the dog food supplementing the trace elements by utilization of a common pet food production puffing technology in China is developed, is a major breakthrough for the pet food processing technology in China, makes up for blanks in the pet market in China, and takes the lead in the pet food processing technologies in Tianjin and surrounding areas.

The invention relates to a domestic dog food facilitating calcium absorption and a preparation method thereof. The domestic dog food comprises the following components in parts by weight: 10-15 parts of calcium lactate, 0.001-0.005 part of vitamin D3, 0.0005-0.002 part of vitamin A, 40-80 parts of saccharose, 2-4 parts of flavouring agent and 3-8 parts of corn starch. By adopting the domestic dog food disclosed in the invention, calcium lacking in the body of a domestic dog can be supplemented, and calcium absorption can be increased. In addition, the domestic dog food has the advantages of good taste, high bioavailability, simple production equipment, easy operation and low cost. Defects of incomplete absorption, poor taste and the like of conventional dog calcium formulation are overcome, and a new path of producing calcium supplement dog food by adopting the general bulking technology for producing pet food domestically is opened up. The preparation method of the domestic dog food is a significant breakthrough of domestic pet food processing technology, and the blank of domestic pet market is filled up. The applicant becomes a leader enterprise for pet food processing technology in Tianjin and surrounding areas.

The invention discloses a sodium ferulate orally disintegrating tablet and its preparation, wherein the tablet is prepared by using sodium ferulate as raw material, using bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, using bonding agent or dressing material based on specific situation, or charging right amount of effervescent agent, then using specific preparing procedure and employing a tablet compressing machine for pelleting. The invention realizes quick disintegrating speed, good taste, the tablet can be taken under the condition of waterless, it has the advantages of fast effect, improved compliance for the patients, and increased curative effect of the medicament.

The invention discloses a ranolazing dispersible tablet, which is prepared by the following steps: taking ranolazing as a raw material and adding ingredients. The ranolazing dispersible tablet provided by the invention has the advantages that the disintegration is quick, the absorption is quick, the bioavailability is high, the medicine-taking is convenient, the residue of the intestinal tract isless, the side effect is less, the taste is sweet and fragrant and the patient medication compliance is especially easy to be improved.

The invention relates to a calcium gluconate orally disintegrating tablet which is prepared by using calcium gluconate as raw material, using bulking agent, crumbling agent, flavoring agent, flow aid, and lubricating agent as adjuvant, and using bonding agent clothing sheet material as required, or adding right amount of effervescent agent. The preparing process employs a tablet compressing machine for pelleting.

The invention relates to a pet food calcium-supplement cat food and a preparation method thereof. The pet food calcium-supplement cat food comprises the following components in parts by weight: 28-40 parts of calcium-containing additive, 0.0018-0.006 part of vitamin, 18-50 parts of cane sugar, 7-15 parts of flavoring agent, 5-20 parts of starch, 0.5-2 parts of taurine and 10-40 parts of bread yeast powder. The main preparation method comprises the following steps: respectively mixing base stock and the vitamin, as well as the calcium-containing additive and the vitamin; shaping the base stock, carrying out spraying, drying and detecting and the like to prepare into finished product. The calcium-supplement cat food in the invention is chewed in an oral cavity, and is evenly distributed in a stomach; 10% of drug stays in the stomach for 5.5h; the drug has the characteristics of less residual in an intestinal tract, low side effect and high bioavailability, can effectively avoid gastric acid corrosion drug, is beneficial for improving the stability of the drug, can be widely used for cats in different ages, and also can be simultaneously used together with other cat food.

A oral-cavity effervescent talbet for treating cardiovascular and cerebrovascular diseases, such as coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction, etc. is prepared from breviscapine, diluent, disintegrant, effervescent agent, flavouring, flowing aid,and lubricant.