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Protein compound liquid for improving skin glossiness and preparation method thereof

A technology for improving skin and gloss, applied in the field of medical cosmetology, it can solve the problems of limited minimally invasive recovery effect, inability to meet multi-functional skin care requirements, and single function.

Inactive Publication Date: 2021-06-04
武汉美吉高科生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there are still two problems with this type of technology today. One is that it relies on the body's own repair, and its minimally invasive recovery effect is limited and the effect is relatively slow; the other is that it has a single function and cannot meet the multi-functional skin care requirements.

Method used

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  • Protein compound liquid for improving skin glossiness and preparation method thereof
  • Protein compound liquid for improving skin glossiness and preparation method thereof
  • Protein compound liquid for improving skin glossiness and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] This example provides a method for preparing exosomes.

[0041] Its specific operation is as follows:

[0042] (1) Take the jelly between the umbilical cord blood vessels and between the blood vessels and the adventitia, cut them into tissue pieces, separate and culture them to obtain primary mesenchymal stem cells, and subculture the primary mesenchymal stem cells, Collect 2-3 generations of passaged cells.

[0043] (2) The passaged cells were cultured for 36 hours in serum-free medium HyloneMEM empty medium, and the cell supernatant was collected;

[0044] (3) Centrifuging the cell supernatant to remove cell debris, then performing ultrafiltration to remove impurities, and collecting the ultrafiltrate;

[0045] (4) Add TotalexosomeIsolation exosome extract to the ultrafiltrate and incubate overnight, then concentrate by centrifugation to obtain a concentrated solution, filter and sterilize, and freeze-dry at -80°C to obtain a freeze-dried exosome powder .

Embodiment 2

[0047] This example provides a protein compound solution for improving skin gloss with different proportions of raw materials.

[0048] Its specific preparation method is as follows:

[0049] Type I collagen, tranexamic acid, vitamin C and sodium hyaluronate were added to physiological saline according to the ratio shown in Table 1 and mixed to obtain a mixed solution;

[0050] The exosome freeze-dried powder prepared in Example 1 was added to the mixed solution according to the ratio in Table 1 and mixed to obtain different types of protein compound solutions.

[0051] The weight percent of each raw material is shown in Table 1.

[0052] The weight percent (wt %) of protein compound solution of table 1

[0053]

[0054]

Embodiment 3

[0069] In this embodiment, the products of embodiment 2 and comparative examples 1-2 are tested.

[0070] The specific operation steps of the test are as follows:

[0071]Screen and test those who are not allergic to the components in the protein compound liquid of the embodiment and the comparative example, 100 cases of surgery, including 50 cases of men and 50 cases of women, whose age range is 30 to 40 years old, and are divided into 10 groups , five men and five men in each group.

[0072] Among them, the CBS-807 skin analysis system was used to detect the spots, moisture, wrinkles, elasticity and skin color of the skin before the experiment.

[0073] The subjects who used the S2-1 model product were the experimental group 1, the subjects who used the S2-2 model product were the experimental group 2, the subjects who used the S2-3 model product were the experimental group 3, and the S2-4 model was used as the experimental group The subjects of the product are the experim...

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Abstract

The invention provides a protein compound solution for improving skin glossiness and a preparation method thereof. The protein compound solution comprises the following components in percentage by weight of 0.2 to 2 weight percent of collagen, 0.01 to 0.05 weight percent of tranexamic acid, 0.02 to 0.06 weight percent of vitamin C, 0.1 to 0.5 weight percent of sodium hyaluronate, 0.5 to 2 weight percent of exosome and the balance of normal saline. According to the compound liquid, collagen and sodium hyaluronate are added, the thickness of skin is increased, meanwhile, the exosome is added, the recovery speed of a minimally invasive wound is increased, the recovery effect is further enhanced, and by adding tranexamic acid and vitamin C, the skin can be whitened while wrinkles are removed.

Description

technical field [0001] The invention belongs to the field of medical cosmetology, and in particular relates to a protein compound solution for improving skin gloss and a preparation method thereof. Background technique [0002] Nowadays, in order to pursue high-speed, fast and more effective skin care, people are gradually changing from the traditional external skin care mode to medical beauty skin care. [0003] Deep activation is to use extremely fine microneedles to deliver physiological saline to the subcutaneous area in a fixed-point, fixed-layer, and quantitative manner. The skin starts a self-healing system due to minimal trauma. In the process of repairing the subcutaneous minimally invasive surface, various cell repair factors will be produced. , Various factors cooperate with each other to promote self-protection and regeneration at different levels, so as to continuously increase the thickness of the subcutaneous layer, so as to achieve the effect of smoothing wri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/65A61K8/44A61K8/67A61K8/73A61Q19/00A61Q19/02A61Q19/08C12N5/0775
CPCA61K8/44A61K8/65A61K8/676A61K8/735A61K8/99A61K2800/5922A61Q19/00A61Q19/02A61Q19/08C12N5/0668C12N2509/00
Inventor 汪良明黄嘉钰汪福强汪洋汪杰彭强
Owner 武汉美吉高科生物科技有限公司
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