Preparation method of traditional Chinese medicine wall-broken decoction pieces

A technology for broken wall decoction pieces and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., and can solve the problems of rapid dissolution of unfavorable medicinal ingredients, inability to form ultrafine powder, and difficulty in dissolving, etc. Conducive to human body absorption, high medicinal value, beneficial to absorption effect

Pending Publication Date: 2021-06-22
云南泰华丰功药业有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The broken-walled decoction pieces prepared by the current technology are not only fast, but also have small particles, which are difficult to dissolve during actual use, which is not conducive to the rapid dissolution of medicinal ingredients
In addition, there are still some deficiencies in the molding of the particles of the current broken-walled decoction pieces, and some superfine powders cannot even be molded, and the stability is relatively poor
Therefore, research and development of a preparation method of broken Chinese medicine decoction pieces, give full play to the advantages of using the whole ingredients of Chinese medicine broken wall decoction pieces, retain all the medicinal ingredients of traditional Chinese medicine by breaking the wall, which is more conducive to the absorption of medicinal ingredients by users , in order to alleviate the problem that the existing traditional Chinese medicine granules can only extract part of the medicinal ingredients after adding water to concentrate, it becomes very necessary and urgent

Method used

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  • Preparation method of traditional Chinese medicine wall-broken decoction pieces
  • Preparation method of traditional Chinese medicine wall-broken decoction pieces

Examples

Experimental program
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Effect test

Embodiment 1

[0022] A preparation method of broken ginseng decoction pieces, comprising the steps of:

[0023] (1) Picking and cleaning the ginseng, drying it, and passing it through a 100-120 mesh sieve to obtain coarse ginseng powder;

[0024] (2) Sterilize the ginseng coarse powder processed in step (1) at 60° C. in an incubator, and then irradiate it for 25 minutes under the intensity of an ultraviolet lamp of 1200W to carry out embrittlement treatment;

[0025] (3) Dry the brittle ginseng coarse powder until the material moisture is 8%, finely pulverize it to 30 mesh, then place the fine powder in a high-frequency nano-impact mill, and ultrafine pulverize it at -2°C for 3 hours;

[0026] (4) Put the micropowder after superfine pulverization in step (3) into a continuous fluidized bed drying granulator for granulation to obtain broken-wall decoction pieces of ginseng.

Embodiment 2

[0028] A preparation method for broken-wall decoction pieces of dendrobium, comprising the steps of:

[0029] (1) Dry the dendrobium after picking and cleaning, and pass through a 120 mesh sieve to obtain the coarse powder of dendrobium;

[0030] (2) The dendrobium coarse powder treated in step (1) is sterilized at 70° C. in an incubator, and then irradiated for 20 minutes under the intensity of an ultraviolet lamp of 1400W to carry out embrittlement treatment;

[0031] (3) Dry the embrittled dendrobium coarse powder until the material moisture is 7%, finely pulverize it to 60 mesh, then place the fine powder in a high-frequency nano-impact mill, and ultrafine pulverize it at -3°C for 2 hours;

[0032] (4) Put the micropowder after step (3) into a continuous fluidized bed drying and granulating machine for granulation to obtain broken-wall decoction pieces of Dendrobium nodii.

Embodiment 3

[0034] A preparation method of notoginseng broken wall decoction pieces, comprising the steps of:

[0035] (1) Dry the notoginseng after sorting and cleaning, and pass through a 100-mesh sieve to obtain coarse powder of notoginseng;

[0036] (2) Sterilize the notoginseng coarse powder treated in step (1) at 80° C. in an incubator, and then irradiate for 15 minutes under the intensity of an ultraviolet lamp of 1600W to carry out embrittlement treatment;

[0037] (3) Dry the embrittled notoginseng coarse powder until the moisture content of the material is 8%, finely pulverize it to 30 mesh, then place the fine powder in a high-frequency nano-impact mill, and pulverize it at -4°C for 1 hour;

[0038] (4) Put the micropowder after the superfine pulverization in step (3) into a continuous fluidized bed drying granulator for granulation to obtain broken-wall decoction pieces of notoginseng.

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Abstract

The invention belongs to the technical field of preparation of traditional Chinese medicine decoction pieces, and discloses a preparation method of traditional Chinese medicine wall-broken decoction pieces, which comprises the following steps: (1) selecting and cleaning medicinal materials, drying, and sieving with a 100-120-mesh sieve to obtain medicinal material coarse powder; (2) sterilizing the medicinal material coarse powder treated in the step (1) in a constant-temperature box, and then carrying out ultraviolet radiation for embrittlement treatment; (3) drying the embrittled crude powder of the medicinal materials, performing fine crushing, then putting the fine powder into a high-frequency nano impact mill, and performing superfine crushing for 1-3 hours; and (4) putting the micro powder subjected to superfine grinding in the step (3) into a continuous fluidized bed drying granulator, and granulating to obtain the traditional Chinese medicine wall-broken decoction pieces. According to the wall-breaking method, plant cell walls can be broken, effective components in the medicinal materials can be reserved to the maximum extent while the wall breaking rate reaches 99%, absorption of the human body is facilitated, the treatment effect is improved, the effective components can be 5-10 times that of a traditional mode, the effective components of traditional Chinese medicine cannot be lost, and the medicinal value is high.

Description

technical field [0001] The invention belongs to the technical field of preparation of decoction pieces of traditional Chinese medicine, and in particular relates to a preparation method of broken-wall decoction pieces of traditional Chinese medicine. Background technique [0002] Broken-wall decoction pieces of traditional Chinese medicine is a traditional Chinese medicine decoction piece processed in powder form by using modern ultrafine pulverization technology. Ultrafine pulverization technology is a new technology that has developed rapidly in recent years. For example, the active ingredients in Chinese medicinal materials such as Ganoderma lucidum, Cordyceps, and Panax notoginseng are distributed in the cells. When decocting conventional decoction pieces, only part of the active ingredients can be released. The utilization rate is only 10-30%. However, if the Chinese medicine decoction piece is crushed to about 300 mesh, the cell wall breaking rate will reach more than ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K36/8984A61K36/54A61K36/8994
CPCA61K36/258A61K36/8984A61K36/54A61K36/8994A61K2236/13A61K2236/17A61K2236/15
Inventor 罗家瑞周文峰周华健
Owner 云南泰华丰功药业有限公司
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