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Medical multifunctional hemostatic dressing and preparation method thereof

A hemostatic dressing and multi-functional technology, applied in the field of biomedical materials, can solve problems such as low comprehensive performance, and achieve the effects of reducing secondary injury, promoting hemostasis, and shortening coagulation time.

Active Publication Date: 2021-06-25
HENAN YADU IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the research hotspots of traditional hemostatic dressings mainly focus on how to stop bleeding, and there are few studies on improving its comprehensive performance.

Method used

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  • Medical multifunctional hemostatic dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A medical multifunctional hemostatic dressing, characterized in that, from the side close to the skin, the medical multifunctional hemostatic dressing is a functional bottom layer, a hydrophilic layer and a protective layer; the functional bottom layer is a non-woven fabric loaded with porous slow-release particles; The hydrophilic layer is a porous sponge loaded with amino-modified pumice; the protective layer is a thermoplastic polyurethane film.

[0037] The non-woven fabric loaded with porous sustained-release particles comprises the following preparation process:

[0038] (1) Take 9 parts of reed flowers to remove impurities and wash them, then mix them with 4 parts of sodium carbonate and 55 parts of deionized water and react in a water bath at 105°C for 0.7h, filter, wash, dry and then mix the reed flowers with citric acid and sodium hypophosphite, mixed with water, reacted for 3.5 hours under hydrothermal conditions at 125°C, filtered, washed, and then dried in ...

Embodiment 2

[0048] A medical multifunctional hemostatic dressing, characterized in that, from the side close to the skin, the medical multifunctional hemostatic dressing is a functional bottom layer, a hydrophilic layer and a protective layer; the functional bottom layer is a non-woven fabric loaded with porous slow-release particles; The hydrophilic layer is a porous sponge loaded with amino-modified pumice; the protective layer is a thermoplastic polyurethane film.

[0049] The non-woven fabric loaded with porous sustained-release particles comprises the following preparation process:

[0050] (1) Take 8 parts of reed flowers to remove impurities and wash them, then mix them with 3 parts of sodium carbonate and 50 parts of deionized water and react in a water bath at 100°C for 1 hour, filter, wash, and dry them, then mix the reed flowers with citric acid and Sodium hypophosphite was mixed with water, reacted under hydrothermal conditions at 120°C for 4 hours, filtered, washed, and then ...

Embodiment 3

[0060] A medical multifunctional hemostatic dressing, characterized in that, from the side close to the skin, the medical multifunctional hemostatic dressing is a functional bottom layer, a hydrophilic layer and a protective layer; the functional bottom layer is a non-woven fabric loaded with porous slow-release particles; The hydrophilic layer is a porous sponge loaded with amino-modified pumice; the protective layer is a thermoplastic polyurethane film.

[0061] The non-woven fabric loaded with porous sustained-release particles comprises the following preparation process:

[0062] (1) Take 10 parts of reed flowers to remove impurities and wash them, then mix them with 5 parts of sodium carbonate and 60 parts of deionized water and react in a water bath at 110°C for 0.5h, filter, wash, dry and then mix the reed flowers with citric acid and sodium hypophosphite, mixed with water, reacted under hydrothermal conditions at 130°C for 3 hours, filtered, washed, and then dried in a...

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Abstract

The invention relates to the technical field of biomedical materials, and discloses a medical multifunctional hemostatic dressing and a preparation method thereof. The medical multifunctional hemostatic dressing sequentially comprises a functional bottom layer, a hydrophilic layer and a protective layer from the side close to the skin, The functional bottom layer is a non-woven fabric loaded with porous slow-release particles. The hydrophilic layer is porous sponge loaded with amino modified pumice. And the protective layer is a thermoplastic polyurethane film. Compared with the prior art, the dressing provided by the invention not only has relatively strong imbibition and liquid locking capabilities and can activate a blood coagulation system in a short time to quickly stop bleeding, but also provides a slightly moist environment for wound healing and can promote wound healing, and the dressing is not adhered to new granulation tissues, so that secondary pain caused by dressing change is reduced.

Description

technical field [0001] The invention relates to the technical field of biomedical materials, in particular to a medical multifunctional hemostatic dressing and a preparation method thereof. Background technique [0002] As the largest organ of the human body, the skin plays a role in maintaining the balance and stability of the human environment. However, daily life, surgery, etc. will cause skin damage and blood vessel rupture, which in turn will cause a series of effects on the body. Therefore, suitable materials are needed for hemostasis and repair of wounds. [0003] Traditional treatment methods mainly use hemostatic drugs and hemostatic dressings. Although hemostatic drugs have hemostatic effect, they are not easy to store, consume a large amount, easily cause allergies, easily form thrombus, have poor air permeability, and the wound is prone to redness and pus. Hemostatic dressings have become the focus of current research because of their advantages such as being m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/24A61L15/18A61L15/26A61L15/40A61L15/44A61L15/46A61L24/00A61L24/04A61L24/06A61L24/08
CPCA61L15/18A61L15/28A61L15/24A61L15/40A61L15/26A61L15/425A61L15/46A61L15/44A61L24/0005A61L24/0015A61L24/046A61L24/06A61L24/08A61L24/0036A61L2300/232A61L2300/30A61L2300/404A61L2300/418A61L2300/602A61L2400/04C08L5/08C08L5/04C08L1/286C08L29/04C08L71/02C08L79/00
Inventor 张正男段书霞邵蕊娜闫钧付迎坤常聪周静储旭韩颖柳小军田林奇林建香郭文远
Owner HENAN YADU IND
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