A moisture-permeable, hemostatic, antibacterial wound dressing and preparation method thereof

A wound dressing and moisture-permeable technology, applied in the medical field, can solve the problems of weak antibacterial effect, significant antibacterial ability, and biological cytotoxicity of ZnO particles, and achieve good moisture permeability, good antibacterial ability, and simple preparation process.
CN113069587BActive Publication Date: 2022-04-29JIANGNAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGNAN UNIV
Publication Date
2022-04-29

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Abstract

The invention discloses a moisture-permeable, hemostatic and antibacterial wound dressing and a preparation method thereof, belonging to the field of medical technology. The present invention first synthesized novel quaternary ammonium antibacterial agent QAS 18 , and then graft the quaternary ammonium antibacterial agent onto the surface of ZnO nanoparticles to prepare ZnO‑QAS 18 particles, followed by electrospinning and spray coating of zein protein and ZnO‑QAS 18 The wound dressing was prepared in the form of granules. The wound dressing of the invention has good moisture permeability, certain hemostatic ability, remarkable antibacterial effect, good biocompatibility, convenient preparation process and no pollution.
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Description

technical field

[0001] The invention relates to a moisture-permeable, hemostatic and antibacterial wound dressing and a preparation method thereof, belonging to the field of medical technology. Background technique

[0002] The problem of wound infection caused by microorganisms has always been a threat to human health. Wound infections caused by pathogens such as bacteria often lead to problems such as suppuration and inflammation. If the bacterial infection in the wound is not treated in a timely and effective manner, it may even cause the body to die. In a natural environment, damaged skin is easily invaded by microorganisms such as bacteria, so timely treatment of wounds can largely avoid infection.

[0003] Zein is the main storage protein in corn with abundant reserves and wide sources. As a natural plant protein, zein has good biocompatibility and degradability. Zein molecular chains are rich in sulfur-containing amino acids and hydrophobic amino acids, so disulfide ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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