Preparation for improving sleep by using phellinus igniarius and preparation method thereof

A technology for improving sleep and Phellinus, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, and medical raw materials derived from fungi, etc. Problems, achieve the effect of soothing emotions, improving sleep, and soothing emotions

Pending Publication Date: 2021-07-13
XUZHOU UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, apart from the chemical sleeping pills and sedatives that directly induce sleep, there are no ideal drugs that can improve sleep but have no effect on direct sleep.
With the clinical use, the side effects of chemical hypnotics and sedatives that directly lead to sleep are becoming more and more prominent, and it is not easy to take long-term medication, and it is not suitable as a daily sleep-improving drug application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1 prepares the preparation utilizing Phellinus phylloxera to improve sleep

[0016] Consists of the following components: Phellinus extract 2500g, Vitamin B 6 4g, lactose 300g, magnesium stearate 100g.

[0017] The Phellinus extract is prepared by the following method: take Phellinus, pulverize, pass through a 60-mesh sieve, add 12 times the amount of water, and extract at 90°C for 3 hours; repeat the extraction once and combine twice The extract solution was cooled to room temperature, concentrated under reduced pressure to 1 / 8 of the original volume, added 95% ethanol solution of 3 times the volume of the concentrated solution, left standing at 4°C for 8 hours, and centrifuged to collect the precipitate; Reconstituted, spray-dried, that is.

[0018] The preparation method of the preparation for improving sleep by using Phellinus fungus is as follows: take the Phellinus fungus extract, vitamin B 6 and lactose, mixed evenly by equal addition method, using...

Embodiment 2

[0019] Embodiment 2 prepares the preparation that utilizes Phellinus to improve sleep

[0020] Composed of the following components: Phellinus extract 2000g, Vitamin B 6 3g, lactose 320g, magnesium stearate 90g.

[0021] The Phellinus extract is prepared by the following method: take Phellinus, pulverize, pass through an 80-mesh sieve, add 8 times the amount of water, and extract at 100°C for 2 hours; repeat the extraction once and combine twice The extract solution was cooled to room temperature, concentrated under reduced pressure to 1 / 10 of the original volume, added 2 times the volume of the concentrated solution in 95% ethanol solution, left standing at 4°C for 8 hours, and centrifuged to collect the precipitate; the precipitate was washed with water Reconstituted, spray-dried, that is.

[0022] The preparation method of the preparation for improving sleep by using Phellinus fungus is as follows: take the Phellinus fungus extract, vitamin B 6 and lactose, mixed evenly...

Embodiment 3

[0023] Embodiment 3 prepares the preparation that utilizes Phellinus to improve sleep

[0024] Consists of the following components: Phellinus extract 3000g, Vitamin B 6 5g, lactose 280g, magnesium stearate 90g.

[0025] The Phellinus extract is prepared by the following method: take Phellinus, pulverize, pass through an 80-mesh sieve, add 20 times the amount of water, and extract at 85°C for 3 hours; repeat the extraction once, and combine the two The second extract was cooled to room temperature, concentrated under reduced pressure to 1 / 5 of the original volume, added 3 times the volume of 95% ethanol solution of the concentrated solution, allowed to stand at 4°C for 8 hours, and centrifuged to collect the precipitate; It is reconstituted with water, spray-dried, and obtained.

[0026] The preparation method of the preparation for improving sleep by using Phellinus fungus is as follows: take the Phellinus fungus extract, vitamin B 6 and lactose, mixed evenly by equal add...

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PUM

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Abstract

The invention discloses a preparation for improving sleep by using phellinus igniarius. The preparation is prepared from the following components: 2000 to 3000g of phellinus igniarius extract, 3 to 5g of vitamin B6, 280 to 320g of lactose and 90 to 110g of magnesium stearate. The phellinus igniarius extract is prepared by the following method: taking phellinus igniarius, crushing, adding water, and extracting; repeatedly extracting for one time, combining the two leaching solutions, cooling to room temperature, concentrating under reduced pressure, adding 95% ethanol solution, standing, centrifugally separating and collecting precipitate; and redissolving the precipitate with water, and carrying out spray drying, thereby obtaining the product. According to the preparation for improving sleep by using the phellinus linteus, the phellinus linteus extract has the effects of resisting anxiety, calming and hypnotizing; vitamin B6 is a necessary substance for maintaining normal functions of a nervous system, and can more effectively pacify emotion. The preparation disclosed by the invention can effectively relieve mood and improve sleep for high-pressure people and people with poor sleep.

Description

technical field [0001] The invention relates to a preparation for improving sleep by using Phellinus fungus and a preparation method thereof. Background technique [0002] As our country enters the reality of aging and faster and faster pace of life, insomnia has become a serious factor affecting people's health and quality of life. Insomnia is the inability to fall asleep or stay asleep, resulting in a lack of sleep. Also known as sleep and sleep maintenance disorders, it is a common disease caused by various reasons such as difficulty in falling asleep, too short sleep depth or frequency, early awakening and insufficient sleep time or poor quality. Insomnia often brings great pain and psychological burden to patients, and can damage other aspects of the body due to the abuse of insomnia drugs. [0003] At present, except for the chemical hypnotics and sedatives that directly cause sleep, there is no ideal drug that can improve sleep but has no effect on direct sleep. Al...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P25/20A61K31/4415
CPCA61K36/07A61K31/4415A61P25/20A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 陈安徽刘恩岐巫永华邵颖张建萍
Owner XUZHOU UNIV OF TECH
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