Preparation method of lucid ganoderma extracting solution

A technology for extracting liquid and extracting liquid, which is applied to skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc. Ingredient content, shelf life extension, shelf life extension effect

Active Publication Date: 2021-07-16
SICHUAN ACAD OF CHINESE MEDICINE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In recent years, there have been extensive researches on Ganoderma lucidum extract, which is unstable and prone to precipitation and deterioration after long-term storage. As a traditional Chinese medicine extract, the existing refining methods mainly include alcohol precipitation, adsorption clarification, enzymatic clarification, Adding flocculants, centrifugation and ultrafiltration membrane filtration, these methods are cumbersome to operate, and after removing impurities through precipitation, the active ingredients are lost, reducing the content of active ingredients and reducing the efficacy, especially when the Ganoderma lucidum extract is used in In cosmetics, it is more unstable, prone to precipitation and deterioration, lower stability, lower efficacy, and affect use

Method used

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  • Preparation method of lucid ganoderma extracting solution
  • Preparation method of lucid ganoderma extracting solution
  • Preparation method of lucid ganoderma extracting solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 Preparation of high-quality Ganoderma lucidum extract of the present invention

[0022] Take Ganoderma lucidum, add 10-20 times the amount of water to decoct, decoct 2-4 times in total, each time for 0.5-1.5 hours, combine the decoction liquid, concentrate, and obtain Ganoderma lucidum extract containing 0.1g of Ganoderma lucidum crude drug per 1ml, Take 100ml of Ganoderma lucidum extract, let it stand at 2°C for 20d, filter it with a 0.22um microporous membrane, add 5ml of 0.1% ZTC1+1 (natural clarifier) ​​solution to the filtrate, first stir at 550r / min for 1min, then stir at 35r / min for 15min , centrifuged at a speed of 3500r / min for 15min, took the supernatant and added 65ml of glycerol, mixed evenly, and obtained.

Embodiment 2

[0023] Example 2 Preparation of high-quality Ganoderma lucidum extract of the present invention

[0024] Take Ganoderma lucidum, add 10-20 times the amount of water to decoct, decoct 2-4 times in total, 0.5-1.5 hours each time, combine the decoction liquid, concentrate, and obtain Ganoderma lucidum extract containing 0.5g of Ganoderma lucidum crude drug per 1ml, Take 100ml of Ganoderma lucidum extract, let it stand at 4°C for 30d, filter it with a 0.45um microporous membrane, add 5ml of 0.1% chitosan solution to the filtrate, stir at 500r / min for 2min, then 40r / min for 10min, then stir at a speed of 3000r / min Centrifuge under the condition of 1 / min for 20min, take the supernatant and add 45ml of glycerin and 1ml of S68 (xinanediol), mix well, and get final product.

Embodiment 3

[0025] Example 3 Preparation of high-quality Ganoderma lucidum extract of the present invention

[0026] Take Ganoderma lucidum, add 10-20 times the amount of water to decoct, decoct 2-4 times in total, 0.5-1.5 hours each time, combine the decoction liquid, concentrate, and obtain Ganoderma lucidum extract containing 0.5g of Ganoderma lucidum crude drug per 1ml, Take 100ml of Ganoderma lucidum extract, let it stand at 8°C for 40d, filter it with a 0.45um microporous membrane, add 5ml of 0.1% gelatin solution to the filtrate, first stir at 600r / min for 1min, then 45r / min for 10min, then at a speed of 4000r / min Centrifuge under the condition of 30min, take the supernatant, add 45ml of butanediol and 1ml of S68, mix well, and obtain.

[0027] Further illustrate the beneficial effect of the present invention by test example below:

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Abstract

The invention discloses a preparation method of a high-quality lucid ganoderma extracting solution. The preparation method of the high-quality lucid ganoderma extracting solution comprises the following steps of taking lucid ganoderma as a raw material, adding water, extracting, concentrating to obtain the lucid ganoderma extracting solution, standing at 2-8 DEG C for 20-40 days, adding a clarifying agent, filtering, adding auxiliary materials acceptable in cosmetics, medicines or foods, and uniformly mixing to obtain the lucid ganoderma extracting solution. The lucid ganoderma extracting solution prepared by the method is excellent in quality, not easy to precipitate and high in stability, can be applied to the fields of the cosmetics, the medicines, the foods and the like, and is simple in method, easy to operate and excellent in market application prospect.

Description

technical field [0001] The invention specifically relates to a preparation method of ganoderma lucidum extract. Background technique [0002] As a traditional Chinese medicinal material with thousands of years of medicinal history, Ganoderma lucidum has high medicinal value. Studies have confirmed that the chemical components in Ganoderma lucidum are mainly ergosterol, fungal lysozyme and acid protease. The water-soluble extract contains water-soluble protein, aspartic acid, glutamic acid, arginine, lysine and other amino acids, polypeptides and polysaccharides. Modern scientific research has found that the polysaccharides in Ganoderma lucidum have the effects of improving immunity, lowering blood lipids, and anti-oxidation. [0003] In recent years, there have been extensive researches on Ganoderma lucidum extract, which is unstable and prone to precipitation and deterioration after long-term storage. As a traditional Chinese medicine extract, the existing refining methods...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9728A61Q19/00A61K36/074A23L31/00
CPCA61K8/9728A61Q19/00A61K36/074A23L31/00A61K2800/10A61K2236/331A61K2236/51A61K2236/53A23V2002/00A23V2250/208
Inventor 罗霞许晓燕罗舒
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
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