A kind of traditional Chinese medicine for treating rheumatoid arthritis
A rheumatoid and arthritis technology, applied in the field of traditional Chinese medicine for the treatment of rheumatoid arthritis, can solve the problems of limited drug efficacy, unbearable cost, and non-curative indicators, etc., achieve longer-lasting therapeutic effects, lower preparation costs, and lower usage cost effect
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Embodiment 1
[0066] Embodiment 1: the preparation of Chinese medicine
[0067] 1. Take the same amount of Ephedra, Fangfeng, Chuanwu, Asarum, Fenfangji, Diwu, Tripterygium wilfordii, Sophora flavescens, Coix seed, Artemisia annua, Comfrey, Myrrh, Chuanxiong, Frankincense, Qingfengteng, Shenjincao , turmeric, ginseng, Codonopsis pilosula and Araceae medicinal materials are mixed, boiled twice, and the extracts are combined.
[0068] 2. The combined extract was separated by preparative chromatography, and the extract was divided into 20 components. The chromatographic conditions are as follows: Innovative Tongheng DAC100 chromatograph, see the chromatographic separation diagram figure 1 , the preparative chromatographic column is a reverse phase C18 column (100×250mm, 10 μm, Acchrom), mobile phase: A-MeOH, B-0.1%FA / H 2 O, gradient elution conditions: 0-50-80min, 35%-95%-95%A. The flow rate is 320mL / min, and the detection wavelength is 254nm.
[0069] 3. Dry the separated and prepared 20 ...
Embodiment 2
[0108] Embodiment 2: health care insole and health care socks for the treatment of rheumatoid arthritis
[0109] Such as Figure 13 As shown, the present invention provides a kind of health care insole and the matching health care socks 5, wherein the health care insole includes a shoe insole main body 1 and a gel medicine slow-release tablet 2-4 detachably installed on the insole main body, and the gel The drug slow-release tablets 2-4 are in close contact with the main body 1 of the foot and the insole.
[0110] The sole of the health socks 5 is provided with a hollow structure 6-7, and its position corresponds to the gel drug slow-release tablet 2-3. When a person puts on the health care socks 5 and steps on the health care insole, the skin of the human foot directly contacts the drug sustained release tablet 2-3 through the hollow structure 6-7, so that the medicine or health care products in the gel drug sustained release tablet can pass through The skin is released int...
Embodiment 3
[0113] Embodiment 3: the preparation of chitosan / carboxymethyl chitosan drug sustained-release tablet
[0114] The present embodiment provides a kind of preparation method of chitosan / carboxymethyl chitosan medicine slow-release tablet, specifically as follows:
[0115] At a certain temperature, a certain amount of chitosan is dissolved in 2% acetic acid solution by volume to prepare a chitosan-acetic acid solution. Accurately weigh a certain amount of GST into the chitosan-acetic acid solution and stir at 50°C for 5min. Under magnetic stirring, add 2.5mL of liquid paraffin and emulsify for a period of time. Add a certain amount of Span80, and slowly drop a certain mass fraction of sodium tripolyphosphate solution 2.5mL at a rate of 0.2mL / min, and react for a period of time. Add carboxymethyl chitosan aqueous solution containing a certain quality drop by drop, continue to stir and react for a period of time, centrifuge, freeze-dry and save the sample.
[0116] Chitosan / carb...
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Abstract
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