Cosmetic composition for regulating skin homeostasis balance and application thereof

A composition and cosmetic technology, applied in the directions of cosmetics, cosmetic preparations, preparations for skin care, etc., can solve the problems of products that do not have the dual system regulation of autophagy-lysosome and ubiquitin-proteasome at the same time, etc. To achieve the effect of improving cell purification and detoxification, enhancing activity and delaying aging

Active Publication Date: 2021-09-03
皙美(上海)化工科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, there is no product on the market that satisfies the dual system regulation of autophagy-lysosome and ubiquitin-proteasome

Method used

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  • Cosmetic composition for regulating skin homeostasis balance and application thereof
  • Cosmetic composition for regulating skin homeostasis balance and application thereof
  • Cosmetic composition for regulating skin homeostasis balance and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0048] In the following examples and comparative examples of the present invention, the composition with multi-target anti-aging and anti-wrinkle effects is prepared by the following process:

[0049] S1, preparation of bifidobacteria fermentation product lysate: select bifidobacteria with an inoculum amount of 5% in sterile medium, anaerobic fermentation at 37°C for 20 hours, pasteurization for 30 minutes, and low-temperature centrifugation to collect bifidobacteria cells , adding 6 times the amount of deionized water, resuspending the bifidobacterium bacteria, breaking the wall to release nutrients, and filtering to obtain the lysate of the fermentation product of bifidum yeast.

[0050] S2, preparation of milk extract: take food-grade milk for pre-treatment to remove substances that are prone to corruption, then finely filter, concentrate, separate the target protein through different isoelectric points, separate, and spray dry to obtain the milk extract;

[0051] S3, prepa...

Embodiment 8

[0080] Based on this, considering factors such as efficacy, cost and stability of the composition, preferred embodiment 8 (lysate of Bifida yeast fermentation product: milk extract: peach blossom extract = 1:3:0.2).

Embodiment 6

[0087] Based on this, considering factors such as efficacy, cost and stability of the composition, preferred embodiment 6 (lysate of Bifida yeast fermentation product: milk extract: peach blossom extract = 2:1:0.8).

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Abstract

The invention provides a cosmetic composition for regulating skin homeostasis balance and application thereof. The composition is composed of an active ingredients with a mass fraction of 1-5% and a cosmetic acceptable solvent, and the active ingredients are a bifida ferment lysate, a milk extract and a peach blossom extract according to a mass ratio of (1-4): (1-4): (0.2-0.8). The composition provided by the invention can improve the activity of autophagosome and proteasome, has a synergistic effect, achieves the effects of enhancing the antioxidant capacity of skin and removing skin aging waste so as to delay aging and whiten the skin, and can be used as a functional raw material to be added into cosmetics for application.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a cosmetic composition for regulating the homeostasis of the skin and an application thereof. Background technique [0002] Aging refers to a comprehensive state characterized by morphological changes, functional decline and metabolic disorders in the process of aging. It is an irreversible process that will inevitably occur in all organisms. In 2050, the world's elderly population over the age of 60 will reach 2.1 billion. With the intensification of the aging society, the longevity people pursue is no longer simply life extension, but healthy aging and graceful aging. [0003] Skin aging can be divided into endogenous aging (natural aging) caused by intrinsic factors and exogenous aging secondary to exogenous factors. Endogenous aging is the skin aging caused by biological internal factors, such as age aging, physiological aging, the decline of collagen and elastin synthe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9728A61K8/9789A61Q19/02A61Q19/08
CPCA61K8/986A61K8/9789A61K8/9728A61Q19/02A61Q19/08A61K2800/5922A61K2800/85A61K2800/805
Inventor 周秋娜金荣熙周春亚金炫延尹锺赫金延埈
Owner 皙美(上海)化工科技有限公司
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