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Deer blood formula granules as well as preparation method and application thereof

A technology of formula granules and deer blood, which is applied in the fields of blood diseases, cardiovascular system diseases, digestive system, etc., can solve the problems of primary products, insignificant curative effect, rough product processing, etc.

Pending Publication Date: 2021-09-10
长春金荷药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the northeast and northwest of my country are the main producing areas of deer, and deer resources are very rich, but the processing of deer blood is still in a relatively simple stage, the deep processing technology is not mature enough, the product processing is rough, the product is primary, the variety is single, and the curative effect is not significant , resulting in a great waste of deer blood resources

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  • Deer blood formula granules as well as preparation method and application thereof
  • Deer blood formula granules as well as preparation method and application thereof
  • Deer blood formula granules as well as preparation method and application thereof

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Experimental program
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Effect test

preparation example Construction

[0032] The preparation method of deer blood formula granules of the present invention is characterized in that it specifically comprises the following steps:

[0033] (1) Preparation of deer blood formula granule deer blood powder: deer blood powder is obtained after finely grinding the dried blood of sika deer or red deer;

[0034] (2) Add the deer blood powder into water, the mass ratio of deer blood powder to water is 1:8, and decoct for the first time. After decocting for 1 hour, filter while it is hot (sieve 100 mesh), and collect the first time Filtrate, keep the medicinal residue after filtering for the first time;

[0035] (3) Add water for the second time to the dregs after the first filtration, the mass ratio of dregs to water is 1:6, decoct for the second time, after decocting for 1 hour, filter while hot (sieving 100 mesh), collect the filtrate for the second time, and keep the dregs after the second filtration;

[0036] (4) Add water for the third time to the dr...

Embodiment 1

[0055] Extraction process: Traditional Chinese medicine formula granules refer to Chinese medicine decoction pieces that are extracted with water to make a finished product of a certain specification that can only be used for clinical formulas of traditional Chinese medicine in medical institutions. Since the extraction solvent of formula granules has been stipulated as water, and follow the decoction of traditional Chinese medicine decoction Methods: Therefore, the extraction process of deer blood formula granules is based on its active ingredients or index ingredients and the rate of ointment, and the four main influencing factors of soaking time, water addition, extraction time and frequency are tested to determine the corresponding Extract process parameters.

[0056] The deer blood has been identified to meet the deer blood standard on page 269 of the 2019 edition of the "Standards of Traditional Chinese Medicinal Materials in Jilin Province".

[0057] Selection of extrac...

Embodiment 2

[0097] ("Chinese Pharmacopoeia" 2020 Edition Four General Rules 0104) regulated under the granules.

[0098] Properties: After the investigation of the test samples, the properties of the formula granules are all purple-red to purple-black particles; the gas is slightly fishy and salty, so the properties of the deer blood formula granules are tentatively determined to be purple-red to purple-black particles; Fishy, ​​salty.

[0099] Particle size: According to the particle size determination method (Chinese Pharmacopoeia 2020 edition three appendix 0982 second method, sieving method), the test sample cannot pass the No. 1 sieve and the sum of No. 5 sieve does not exceed 15%, which meets the regulations.

[0100] Solubility: take 10g of granules, heat 200ml of water, stir for 5 minutes, the experimental analysis is shown in Table 6

[0101] Table 6 General inspection of granules

[0102] test group character The total of those that cannot pass through the No. 1 ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine formula granules, and discloses deer blood formula granules as well as a preparation method and application thereof. The preparation method comprises the following steps: processing dry blood of a deer animal such as a sika deer or a red deer, and processing the dried blood and a pharmaceutically acceptable auxiliary material dextrin to prepare the formula granules. The deer blood formula granules are prepared by the following steps: taking dry deer blood, finely grinding, adding water, decocting, filtering, concentrating clear paste, spray-drying, adding an auxiliary material dextrin, drying and granulating to prepare the finished product. The deer blood formula granules have the characteristics that the deer blood extracting solution is subjected to vacuum concentration and spray drying, dry granulation with high efficiency and low cost is adopted, processing parameters are strictly controlled, and the prepared formula granules are high in effective component content, small in dosage and excellent in quality, and sample quality inspection results all conform to regulations of Chinese Pharmacopoeia. The preparation method disclosed by the invention has stable manufacturing technique, the manufacturing process is simple and reasonable, the finished product has high stability, controllable quality and can be stored easily; the preparation method has wide popularization value and is suitable for further amplified production. The deer blood formula granules can be directly used for flexible traditional Chinese medicine clinical formula blending and compound medicine preparation, provides a new way for traditional Chinese medicine clinical medication, and the deer blood formula granules have wide market prospects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formula granules, and in particular relates to deer blood formula granules, a preparation method and application thereof. Background technique [0002] The whole body of deer is full of treasures and has medicinal value. It is a precious traditional Chinese medicine recorded in the Compendium of Materia Medica. At present, deer antler and deer whip have been widely used. Deer blood is also a precious resource. Sweet, salty, warm; GUIXIN, liver, kidney meridian; tonic, nourishing blood, hemostasis. Used for deficiency of essence and blood, low back pain, impotence, nocturnal emission, blood deficiency and palpitations, insomnia, lung impotence and hemoptysis, epistaxis, metrorrhagia, leukorrhea, sweet and salty, returns to the liver and kidney meridians, has the functions of nourishing yin and yang, benefiting It is a very valuable traditional Chinese medicine with the functio...

Claims

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Application Information

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IPC IPC(8): A61K35/14A61K9/16A61P1/14A61P29/00A61P15/10A61P15/00A61P7/06A61P9/06A61P25/20A61P11/00A61P7/04A61P11/02
CPCA61K35/14A61K9/1652A61P1/14A61P29/00A61P15/10A61P15/00A61P7/06A61P9/06A61P25/20A61P11/00A61P7/04A61P11/02
Inventor 赵丽华孙玉徐彦军
Owner 长春金荷药业有限公司