Casein zymolyte with sleep aiding function, casein zymolyte composition and preparation method of casein zymolyte composition

A technology of caseinase and compound composition, which is applied in the direction of drug combinations, medical preparations containing active ingredients, hydrolyzed protein components, etc., can solve the problems of large side effects, insignificant effects, and slight effects of drugs, and achieve excellent effects and effective effects. Visible, sleep-promoting effect

Pending Publication Date: 2021-09-24
北京姿美堂生物技术股份有限公司
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  • Description
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Problems solved by technology

[0003] Among the sleep aid products on the market now, the side effects of the medicine are large, and the health food is mainly melatonin, but the effect of these melatonin health food is not obvious. At the same time, melatonin is a hormone. Addiction, resistance and other problems; there are also some sleep aids and tranquilizing foods, but the effect is minimal

Method used

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  • Casein zymolyte with sleep aiding function, casein zymolyte composition and preparation method of casein zymolyte composition
  • Casein zymolyte with sleep aiding function, casein zymolyte composition and preparation method of casein zymolyte composition
  • Casein zymolyte with sleep aiding function, casein zymolyte composition and preparation method of casein zymolyte composition

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preparation example Construction

[0026] The present invention also provides a method for preparing the enzymatic hydrolyzate of casein, comprising the following steps: 1) ultrasonically treating the bovine casein aqueous solution for 0.5 to 3 hours to obtain the feed liquid to be enzymatically hydrolyzed; 2) compounding the feed liquid to be enzymatically hydrolyzed with Mixing hydrolytic enzymes for enzymolysis to obtain an enzymolysis feed solution; 3) ultrafiltering the enzymolysis feed solution to obtain a casein hydrolyzate.

[0027] In the present invention, the bovine casein aqueous solution is ultrasonically treated for 0.5-3 hours to obtain the feed liquid to be enzymatically hydrolyzed. In the present invention, the bovine casein aqueous solution is preferably obtained by mixing bovine casein with water, and the mass percentage of bovine casein in the bovine casein aqueous solution is preferably 4% to 10%, more preferably 5%. ~9%; the present invention has no special limitation on the source of the ...

Embodiment 1

[0051] Preparation of casein hydrolyzate with sleep-promoting function:

[0052] (a) Raw material pretreatment: Bovine casein (purchased from Shaanxi Chenming Biotechnology Co., Ltd., specifications: 99% casein mass percentage content; dissolved into 5% bovine casein aqueous solution with pure water, and then ultrasonic cell pulverizer (Shanghai Zhengqiao Scientific Instrument Co., Ltd., model ZQ-650, power 650W) ultrasonic 2h;

[0053] (b) Enzymolysis: use compound hydrolase to carry out enzymolysis, compound hydrolase is:

[0054] Papain (purchased from Nanning Pangbo Bioengineering Co., Ltd., 500,000 U / g),

[0055] Bromelain (purchased from Nanning Pangbo Bioengineering Co., Ltd. 500,000 U / g),

[0056] Bacillus subtilisin (purchased from Novozymes (China) Biotechnology Co., Ltd. 500,000 U / g), neutral protease (purchased from Nanning Pangbo Bioengineering Co., Ltd. 200,000 U / g)

[0057] The above four enzymes are prepared according to the mass ratio of 1:1:1:1 to obtain a...

Embodiment 2

[0074] A kind of casein hydrolyzate composition

[0075] The product composition is as follows:

[0076] Casein hydrolyzate 17% (17kg) prepared in embodiment 1, gamma-aminobutyric acid 13% (13kg), tealeaves theanine 5% (5kg), jujube seed powder 5% (5kg), passion fruit Fruit powder 2% (2kg), sour cherry fruit powder 2% (2kg), sorbitol 46% (46kg), microcrystalline cellulose 8% (8kg), food flavor 0.7% (0.7kg) and magnesium stearate 1.3 % (1.3 kg).

[0077] Preparation:

[0078] Pass the above-mentioned casein hydrolyzate, γ-aminobutyric acid, tea theanine, jujube seed powder, passion fruit powder, and sour cherry fruit powder through a 80-mesh sieve;

[0079] Weigh the sieved raw materials and related auxiliary materials according to the formula quantity (the auxiliary materials are sorbitol, microcrystalline cellulose, food flavor, magnesium stearate, mainly to improve the taste, increase the tablet adhesion, disintegrate, smooth properties, etc.), put it into a three-dimens...

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Abstract

The invention provides a casein zymolyte with a sleep aiding function, a casein zymolyte composition and a preparation method of the casein zymolyte composition, and belongs to the technical field of health food. The average relative molecular weight of the casein zymolyte is 1000-3000Da; the content of decapeptide YLGYLEQLLR in the casein zymolyte is 1.5%-2.5%; and the casein zymolyte composition is prepared from the following components in parts by weight: 1-35 parts of casein zymolyte, 1-30 parts of gamma-aminobutyric acid, 1-20 parts of tea leaf theanine, 1-20 parts of semen ziziphi spinosae powder, 1-20 parts of passion fruit powder and 1-20 parts of sour cherry fruit powder. The casein zymolyte has the effects of remarkably improving sleep, improving sleep quality and slowing down nervous mood; and the casein zymolyte composition can effectively promote sleep and shorten sleep time, and compared with the prior art, the casein zymolyte composition is excellent in effect.

Description

technical field [0001] The invention belongs to the technical field of health food, and in particular relates to a casein hydrolyzate with sleep-promoting function, a casein hydrolyzate composition and a preparation method thereof. Background technique [0002] In today's society, the pace of life is gradually accelerating, and modern people's work pressure is increasing day by day, and they often work overtime until late at night; over time, lack of sleep has become a common problem among modern people. Many people have insomnia symptoms due to tension, anxiety, and excessive pressure. Working and studying during the day will lead to lack of energy and sleepiness, which will seriously affect people's health for a long time. Most people have the following symptoms: Difficulty falling asleep, unable to sleep soundly, sleep time is gradually reduced; Waking up early, unable to fall asleep after waking up; Waking up frequently from nightmares, not recovering energy after sleepi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/18A23L33/175A23L33/10A23L19/00A23J3/34A61K38/01A61P25/20
CPCA23L33/18A23L33/175A23L33/10A23L19/01A23J3/344A61K38/01A61K31/197A61K31/198A61K36/725A61K36/185A61K36/736A61P25/20A23V2002/00A23V2200/322A23V2250/55A23V2250/038A23V2250/0646A23V2250/642A23V2250/51084A23V2250/5114A23V2250/264A23V2250/032A61K2300/00
Inventor 徐熙明董彦博宫建辉王胜男
Owner 北京姿美堂生物技术股份有限公司
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