Preparation and application of a probiotics with liver damage protection

Abstract

The invention discloses the preparation and application of a proanthocyanidin preparation with liver damage protection effect, which is prepared by fermentation of grape seed proanthocyanidin powder, fermentation medium and compound bacterial liquid; the compound bacterial liquid is composed of Saccharomyces cerevisiae H2 and fermented milk Bacillus O is mixed, and the addition ratio of Saccharomyces cerevisiae H2 and Lactobacillus fermentum O is 2:3; the fermentation medium consists of the following components: 26-27 parts by weight of glucose, 10-11 parts by weight of peptone, yeast extract 4-5 parts by weight of powder, 1-2 parts by weight of dipotassium hydrogen phosphate, 1-2 parts by weight of ammonium citrate, 0.1-0.3 parts by weight of magnesium sulfate, and 950-1000 parts by weight of water. The preparation and application of the proanthocyanidin preparation with the protective effect on liver damage, through the selection of low-cost crudely extracted commercial grape seed proanthocyanidin powder, its impurities and degree of polymerization are relatively high, and the average degree of polymerization of proanthocyanidin can be reduced and reduced by joint fermentation. It is stably dissolved in the complex bacterial liquid, so that the ingredients of the preparation can be absorbed and utilized by the body to prevent liver damage.

Description

technical field [0001] The invention relates to the technical field of biological preparations, in particular to the preparation and application of a probiotic preparation with liver damage protection. Background technique [0002] my country's grape production is at the leading level in the world. With the rapid development of the grape processing industry, more and more grape waste is produced. At present, some of these wastes are used to produce low-value products such as fertilizers, activated carbon, and biogas raw materials, and most of them are directly treated as garbage. However, grape seeds are not only rich in nutrients such as vitamins, amino acids, and minerals, but also contain a large amount of proanthocyanidins; moreover, proanthocyanidins extracted from grape seeds have strong antioxidant properties and can efficiently scavenge free radicals. Its ability is superior to that of vitamin C. 20 times. Therefore, the rational extraction and utilization of proan...

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the prior art, the present invention provides the preparation and application of a probiotic preparation with liver damage protection, which has the advantages of preventing and treating liver damage diseases caused by oxidative stress, and effectively alleviates the damage caused by oxidative stress in the body. The problem of damage

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