Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of ultrafiltration membrane with anticoagulation hemodialysis function

A hemodialysis and ultrafiltration membrane technology, applied in ultrafiltration, dialysis system, semipermeable membrane separation, etc., can solve problems such as affecting the life safety of dialysis patients, reducing dialysis efficiency, etc., to alleviate coagulation problems, easy operation, anticoagulation The effect of improving blood ability

Pending Publication Date: 2021-11-26
SHENZHEN CHENGDELAI IND CO LTD
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The appearance of blood coagulation will reduce the efficiency of dialysis and even affect the life safety of dialysis patients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] In order to enable those skilled in the art to better understand the present invention, the technical solution of the present invention will be further described below in conjunction with the examples.

[0015] A method for preparing an ultrafiltration membrane with anticoagulant hemodialysis function of the present invention is characterized in that: the specific operation steps are as follows:

[0016] S1: Add hydrogen peroxide to a suspension of a polymer containing monoethylenically unsaturated dicarboxylic anhydride basic structural units in an inert diluent to prepare an unsaturated peroxycarboxyl polymer, and use atom transfer radical polymerization , to obtain a copolymer with free carboxyl groups;

[0017] S2: The copolymer prepared in S1 is blended with film-forming polymers such as PVC (S-70&S-65)&PVP&PEG400 by emulsification spinning,

[0018] S3: Then add dimethylacetamide (DMAc), thickener and vinyl chloride, and heat to 58±5°C; stir to prepare the membra...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of an ultrafiltration membrane with an anticoagulation hemodialysis function. The method comprises the following specific operation steps: S1, adding hydrogen peroxide into a suspension of a polymer containing a monoolefinic unsaturated dicarboxylic anhydride basic structure unit in an inert diluent for reaction to prepare an unsaturated peroxy carboxyl polymer; S2, blending, emulsifying and spinning the copolymer prepared in the S1 and film-making polymers such as PVC (S-70&S-65)& PVP&PEG400; S3, then adding dimethylacetamide (DMAc), a thickening agent and vinyl chloride-vinyl acetate, and heating to 58 + / -5 DEG C; and stirring to prepare a membrane preparation solution, and spinning to prepare the hollow fiber type hemodialysis membrane; S4, reacting for 0.1-500h at the temperature of 20-100 DEG C through an amide reaction catalyst and water according to the mass ratio of (0.001-100): (0.01-10): 1000 to prepare a heparin solution; and S5, after the solvent is fully replaced, soaking the hemodialysis membrane in the heparin solution, grafting heparin to the surface of the hemodialysis membrane, and obtaining the ultrafiltration membrane with the anticoagulation hemodialysis function.

Description

technical field [0001] The invention belongs to the technical field of hemodialysis ultrafiltration membranes, and in particular relates to a method for preparing an ultrafiltration membrane with anticoagulant hemodialysis function. Background technique [0002] Hemodialysis is an effective alternative therapy for the treatment of acute and chronic renal failure. Clinically applied hemodialysis equipment consists of a dialysis machine, a water treatment system, a dialysate system and a dialyzer. Among them, the performance of the dialyzer directly affects the dialysis effect, and the hemodialysis membrane is the main part that determines the performance of the dialyzer. It uses the principle of a semi-permeable membrane and uses the solute gradient, osmotic gradient and water pressure gradient on both sides of the membrane to achieve It is a membrane material for the purpose of removing toxins and excessive water retention in the body, replenishing the substances needed in t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01D67/00B01D69/08B01D69/02B01D61/14A61M1/18
CPCB01D67/0006B01D67/0011B01D67/0093B01D69/08B01D69/02B01D61/145A61M1/16B01D2325/36
Inventor 欧阳葵会刘裕芳
Owner SHENZHEN CHENGDELAI IND CO LTD