Preparation method of drug-loaded vegetable protein nanoparticles
A plant protein and nanoparticle technology, applied in the direction of microcapsules, active ingredients of hydroxyl compounds, non-active ingredients of polymer compounds, etc., can solve the problems of difficult particle size control, wide particle size distribution, and long time consumption, so as to improve production efficiency , Narrow particle size distribution, flexible adjustment effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0030] Take 0.05 g of zein and dissolve it in 50 mL of 80% (V / V) aqueous ethanol to obtain a 1 mg / mL zein solution. Get 0.1g curcumin, it is dissolved in 50mL 95% ethanol, obtains the curcumin solution of 2mg / mL. Weigh an appropriate amount of sodium citrate and citric acid, and prepare a 10 mM sodium citrate-150 μM citric acid buffer solution, so that the final pH value of the buffer solution is in the range of 7.2-7.5. The zein solution and the curcumin solution were divided into two 50mL syringes respectively, and fixed on the same syringe pump, and the flow rate of the syringe pump was set at 12mL / min. Divide the sodium citrate-citric acid buffer into two 100mL syringes and fix them on the same syringe pump, and set the flow rate of the syringe pump to 48mL / min. The four strands of material are fed with a flow rate ratio of 1:1:4:4, and the material is used to rinse the channel before feeding. After the inside of the mixer is stabilized, the product is collected at the ou...
Embodiment 2
[0032] Take 0.05 g of zein and dissolve it in 50 mL of 80% (V / V) aqueous ethanol to obtain a 1 mg / mL zein solution. Get 0.15g curcumin, it is dissolved in 50mL 95% ethanol, obtains the curcumin solution of 3mg / mL. Weigh an appropriate amount of sodium citrate and citric acid, and prepare a 10 mM sodium citrate-150 μM citric acid buffer solution, so that the final pH value of the buffer solution is in the range of 7.2-7.5. The zein solution and the curcumin solution were divided into two 50mL syringes respectively, and fixed on the same syringe pump, and the flow rate of the syringe pump was set at 12mL / min. Divide the sodium citrate-citric acid buffer into two 100mL syringes and fix them on the same syringe pump, and set the flow rate of the syringe pump to 48mL / min. The four strands of material are fed with a flow rate ratio of 1:1:4:4, and the material is used to rinse the channel before feeding. After the inside of the mixer is stabilized, the product is collected at the o...
Embodiment 3
[0034]Take 0.05 g of zein and dissolve it in 50 mL of 80% (V / V) aqueous ethanol to obtain a 1 mg / mL zein solution. Get 0.1g curcumin, it is dissolved in 50mL 95% ethanol, obtains the curcumin solution of 2mg / mL. Weigh an appropriate amount of sodium citrate and citric acid, and prepare a 10 mM sodium citrate-150 μM citric acid buffer solution, so that the final pH value of the buffer solution is in the range of 7.2-7.5. The zein solution and the curcumin solution were divided into two 50mL syringes respectively, and fixed on the same syringe pump, and the flow rate of the syringe pump was set at 12mL / min. Divide the sodium citrate-citric acid buffer solution into two 100mL syringes and fix them on the same syringe pump, and set the flow rate of the syringe pump to 72mL / min. The four strands of material are fed with a flow rate ratio of 1:1:6:6, and the material is used to rinse the channel before feeding. After the inside of the mixer is stabilized, the product is collected a...
PUM
Property | Measurement | Unit |
---|---|---|
concentration | aaaaa | aaaaa |
particle diameter | aaaaa | aaaaa |
particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com