Method for predicting HIFU treatment focus position in human tissue based on nuclear magnetic resonance image

Abstract

The invention relates to a method for predicting an HIFU treatment focus position in a human tissue based on a nuclear magnetic resonance image. The method comprises steps: placing a body membrane in an annular nuclear magnetic resonance equipment working environment, and carrying out nuclear magnetic resonance T1 weighted imaging; processing the image according to a set image processing algorithm, storing and retaining acoustic parameter information of each tissue of the body membrane, pairing the information and fitting a relation curve; after a new biological tissue is put in, performing weighted imaging by the nuclear magnetic resonance equipment T1, performing automatic labeling to obtain an acoustic parameter matrix, and then performing MRI three-dimensional reconstruction to obtain a three-dimensional structure body; and adjusting the position and the incident angle of the high-intensity ultrasonic focused transducer, automatically calculating the position focus offset after determination, and displaying the schematic diagram of the original focus and the offset focus on a computer screen. According to the method, the offset position of the focusing point of the HIFU equipment in the biological tissue can be effectively predicted, so that medical personnel can better utilize diagnosis and treatment equipment to cure a patient.

Description

technical field [0001] The invention relates to a method for predicting focus displacement after ultrasonic waves pass through biological tissues, in particular to a method for predicting focus positions for HIFU treatment in human tissue based on nuclear magnetic resonance images. Background technique [0002] Nowadays, when ultrasound diagnosis is relatively mature, medical ultrasound-related research focuses more on ultrasound treatment of cancer. High Intensity Focused Ultrasound (HIFU) is to focus ultrasound on the target tissue, using the tissue penetration and energy deposition of ultrasound to focus the ultrasound generated outside the body onto the diseased tissue (treatment target) in the body, selectively Destroy malignant tissues deep in the body, and achieve the purpose of treating diseases through the thermal effect, mechanical effect and cavitation effect of ultrasound. This is a non-invasive method with great potential for treating tumors and some non-tumor d...

AI Technical Summary

Problems solved by technology

The HIFU treatment technology guided by B-ultrasound cannot be widely used due to the low resolution of B-ultrasound imaging and poor positioning accuracy

The MRI-guided HIFU medical equipment developed abroad can realize the temperature prediction of the lesion area, image tissue differentiation and detection of necrosis range, etc., but this technology is not yet mature in China and has not entered the stage of clinical treatment.

[0004] The second is that the structure of biological tissues is complex, and the sound field formed when HIFU focuses on transducer radiation will be affected by these factors, and the distribution and control of the sound field directly affect the curative effect of HIFU treatment

Because the individuals treated by HIFU are different, if only relying on the theoretical value in the actual treatment process, it will inevitably cause invariable damage to the non-lesional area

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