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Marine active protein composition with weight-losing and lipid-lowering effects and preparation method of marine active protein composition

A technology of active protein and composition, applied in the field of medicine, can solve the problem of no synergistic combination of phycoerythrin, krill oil and fucoxanthin, and achieve low production cost, obvious effect, and good safety

Pending Publication Date: 2022-01-21
南通中科海洋科学与技术研究发展中心 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the prior art, there is no report on the synergistic combination of phycoerythrin, krill oil and fucoxanthin provided by the present invention

Method used

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  • Marine active protein composition with weight-losing and lipid-lowering effects and preparation method of marine active protein composition
  • Marine active protein composition with weight-losing and lipid-lowering effects and preparation method of marine active protein composition
  • Marine active protein composition with weight-losing and lipid-lowering effects and preparation method of marine active protein composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: A kind of marine active protein composition tablet

[0030] (1) Porphyra was crushed by adding deionized water, put into -20°C refrigerator and freeze-thawed 3 times repeatedly, after the crude extract was filtered, 70% ammonium sulfate solid was added for salting out, and the precipitate was taken for dialysis, and the solution after dialysis was heated at 6000rpm, 4°C, ultrafiltration for 20 minutes, after ultrafiltration, the solution was vacuum freeze-dried, and the purity of food-grade phycobiliprotein was obtained;

[0031] (2) Crush the Antarctic krill, add 95% ethanol and soak at 4-30°C for 2 hours; then stir, separate the extract, and extract the filter residue 3 times; combine the extracts, and remove them at 55°C with a rotary steamer ethanol in the extract to obtain the crude extract of Antarctic krill oil, and then further refined with activated carbon to obtain food-grade krill oil.

[0032] (3) Pulverize the kelp, then add absolute ethanol ...

Embodiment 2

[0034] Embodiment 2: A kind of marine active protein composition oral liquid

[0035] The phycoerythrin, krill oil and fucoxanthin obtained according to steps (1)-(3) in Example 1 were compounded according to 2:10:1, and then added to the mixture containing 20% ​​simple syrup and 0.1% In the distilled water of sodium benzoate, 50 milliliters, 100 milliliters and 200 milliliters of oral liquids of different specifications are made according to the conventional oral liquid preparation method.

Embodiment 3

[0036] Embodiment 3: A kind of marine active protein composition capsule

[0037] Compound phycoerythrin, krill oil and fucoxanthin according to 2:3:1, accounting for 75% of the main raw materials, and then add excipients (medicinal starch: glucose: hydrolyzed gelatin: glycine = 30:10 :1:1) accounted for 25%, mixed evenly, and made into capsules according to the conventional capsule preparation method.

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Abstract

The invention relates to a natural marine-derived active protein composition and a preparation method thereof. The composition comprises phycoerythrin, krill oil and fucoxanthin, wherein the composition can be prepared into tablets, capsules, oral liquid, granules, pills or powder and the like containing the composition with the assistance of other auxiliary materials. The composition disclosed by the invention is extracted by taking natural marine-derived foods as raw materials, is high in safety, has the effects of remarkably reducing body weight and regulating blood fat, and has the effects of remarkably preventing and treating hyperlipidemia, preventing obesity, reducing body weight, regulating blood fat, preventing cardiovascular related diseases and the like.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a marine active protein composition with weight-loss and lipid-lowering effects and a preparation method thereof. Background technique [0002] Modern medicine has proved that excessive obesity can lead to cardiovascular diseases such as hyperlipidemia, hyperglycemia and hypertension, as well as digestive system diseases such as cholecystitis, and even related diseases such as breast cancer and colon cancer. With the continuous improvement of living standards, people's diet structure is biased toward high fat and high sugar, resulting in an increasing incidence of obesity, and the mortality rate of some diseases related to obesity is also increasing. Therefore, obesity and its related diseases have serious impact on people's health. Obese people are often accompanied by diseases related to dyslipidemia. Dyslipidemia refers to the total cholesterol (TC), triglyceride (TG), high...

Claims

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Application Information

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IPC IPC(8): A23L33/185A23L33/105A23L33/115
CPCA23L33/185A23L33/105A23L33/115A23V2002/00A23V2200/332A23V2200/3262A23V2250/21A23V2250/548
Inventor 王广策王立军羌玺顾文辉牛建峰
Owner 南通中科海洋科学与技术研究发展中心
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