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Ganoderma lucidum strain and application thereof

A technology of Ganoderma lucidum and strains, applied in the field of Ganoderma lucidum strains and their uses, can solve the problems of uneven quality of Ganoderma lucidum and large differences in efficacy, and achieve the effects of good application prospects, high yield and stable genetic traits.

Active Publication Date: 2022-03-01
SICHUAN ACAD OF CHINESE MEDICINE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the origin and variety of Ganoderma lucidum, the quality of Ganoderma lucidum varies greatly in my country, and the efficacy varies greatly.

Method used

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  • Ganoderma lucidum strain and application thereof
  • Ganoderma lucidum strain and application thereof
  • Ganoderma lucidum strain and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1, Ganoderma lucidum bacterial strain of the present invention

[0023] The Ganoderma lucidum strain of the present invention is derived from a wild Ganoderma lucidum ZL2 from Mount Emei, Sichuan, and is obtained through systematic breeding. The base is Ganoderma lucidum (Leyss.ex Fr.) Karst., a polyporaceae fungus, which is preserved in the General Microbiology Center (CGMCC) of the China Microbiological Culture Collection Management Committee (CGMCC), and the preservation address is No. 1 Beichen West Road, Chaoyang District, Beijing Court No. 3, the preservation date is November 8, 2021, the preservation number is CGMCC NO.23844, and the classification is named Ganoderma lucidum (Ganodermalucidum).

[0024] Key characteristic properties of this Ganoderma lucidum strain:

[0025] 1. Appearance

[0026] It has typical morphological characteristics of Ganoderma lucidum (Leyss.ex Fr.) Karst.]. The fruiting body is umbrella-shaped, the cap is kidney-shaped, ...

Embodiment 2

[0030] Embodiment 2, preparation of Ganoderma lucidum water extract of the present invention

[0031] The Ganoderma lucidum of Example 1 was powdered in advance, soaked in water for 0.5h, poured out the soaked water, then added 10 times the volume of water, boiled for 1h, filtered to obtain the extract, and the filter residue was extracted twice, and the extract was collected 3 times, and the extracted Liquid filtration, concentration to 1g / ml, water extract of Ganoderma lucidum.

[0032] The beneficial effects of the present invention are demonstrated through specific test examples below.

experiment example 1

[0033] Experimental example 1, research on characteristics and quality of Ganoderma lucidum strain

[0034] 1. Production cycle: about 100 days.

[0035] 2. Appearance: It has the typical morphology of Ganoderma lucidum (Leyss.ex Fr.) Karst.]. The fruiting body is umbrella-shaped, the cap is kidney-shaped, 10-16cm in diameter, 1-2cm thick, hard, light yellow-brown, shiny, with annular ribs and radial wrinkles, thin and truncated edges, often slightly involuted , yellowish white ventrally.

[0036] 3. Yield: According to the conventional bag material cultivation technology, the output is ≥63g / kg. bag material.

[0037] 4. Quality: After testing, 6.53% of extracts, 1.37% of polysaccharides, 0.65% of triterpenes and sterols, all tests should meet the standards of "Pharmacopoeia of the People's Republic of China" (2020 Edition, Part One).

[0038] The experimental results show that the ganoderma lucidum strain has stable and consistent genetic traits, conforms to the standard o...

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Abstract

The invention provides a ganoderma lucidum strain and application thereof, and relates to the field of traditional Chinese medicines. The ganoderma lucidum strain is ganoderma lucidum which is preserved in China General Microbiological Culture Collection Center (CGMCC) and has a preservation number of CGMCC NO.23844. The ganoderma lucidum strain has the characteristics of stable hereditary character, high yield and excellent quality. Meanwhile, the ganoderma lucidum strain has a remarkable anti-inflammatory effect, can be used for preparing anti-inflammatory drugs or cosmetics, can also be used for preparing food or health-care food, and has a good application prospect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a ganoderma lucidum strain and its application. Background technique [0002] Ganoderma sp. belongs to Basidiomycetes, Polyporales, Polyporaceae, Ganoderma. It is an important medicinal fungus and is widely used in traditional Chinese medicine. Pharmacological effects are discussed more. "Shen Nong's Materia Medica" records that Ganoderma lucidum has the functions of strengthening the body, nourishing and strengthening, and prolonging life. Modern pharmacology and clinical trials have further proved that Ganoderma lucidum has anti-aging, anti-virus, anti-oxidation, anti-tumor, enhancing immunity, and liver protection. . Among them, Chizhi is one of the only two Ganoderma lucidums included in the Pharmacopoeia of the People's Republic of China. [0003] "The Pharmacopoeia of the People's Republic of China" (2020 Edition Part One) stipulates that the water content of ...

Claims

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Application Information

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IPC IPC(8): C12N1/14A61K8/9728A61K36/074A61P29/00A61Q19/00A23L31/00A23L33/00C12R1/645
CPCA61K36/074A61P29/00A61K8/9728A61Q19/00A23L31/00A23L33/00A61K2236/331A61K2236/39A61K2236/51A23V2002/00A23V2200/30A23V2250/208Y02A50/30
Inventor 罗霞罗舒高应娟贺黎铭江南姚珂宋怡余梦瑶李芳周州
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
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