Low-dose miniature cone beam CT scanning system and method based on X-ray lens

Abstract

The invention relates to a low-dose miniature cone beam CT scanning system and method based on an X-ray lens. The system comprises a micro-focal spot X-ray source with a capillary focusing X-ray lens, a flat panel detector and an electric rotary translation stage, the micro-focal spot X-ray source with the capillary focusing X-ray lens comprises an X-ray controller and an X-ray tube which are used for emitting scanning light; the electric rotary translation table comprises an electric rotary table and a sample fixing device and is used for carrying out three-dimensional scanning on a sample; the flat panel detector is used for converting an optical signal into a digital signal; and the main control computer is used for controlling the micro-focal spot X-ray source, the flat panel detector and the electric rotary translation stage to carry out signal acquisition, control and image reconstruction. By adopting the system and the method, the problem of image uniformity deterioration caused by the X-ray beam hardening effect can be effectively relieved, penumbra blurring and the hardening artifact effect of the X-ray beam are reduced, the uniformity of the image is improved, and a CT scanning image with higher resolution is obtained.

Description

technical field [0001] The present application relates to the field of CT scanning imaging, in particular to an X-ray lens-based low-dose miniature cone-beam CT scanning system and method. Background technique [0002] With the development of structural and functional molecular imaging system technology, X-ray micro computed tomography (micro-CT), micro magnetic resonance imaging (micro-MRI), micro positron emission tomography (micro-PET) and micro single Photon emission computed tomography (micro-SPECT). Among them, the Micro-CT system can provide high-resolution images, fast data acquisition, high sensitivity to bone tissue and good sensitivity to soft tissue, especially when using contrast agents. [0003] There are two main factors affecting the spatial resolution of Micro-CT scanners: one is geometric factors, and the other is algorithmic factors. In terms of geometric factors, the effective detector aperture size is the basic factor restricting the spatial resolution...

AI Technical Summary

Problems solved by technology

However, the hardening effect of the X-ray beam is difficult to completely eliminate

[0006] Therefore, due to physical effects such as X-beam hardening, scattering, and instrument effects, the images obtained by the current Micro-CBCT system often have blurring artifacts, resulting in low spatial resolution, contrast resolution, and imaging uniformity of the reconstructed image.

Images