Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Hollow fiber membrane oxygenator

An oxygenator and fiber membrane technology, applied in the field of medical devices, can solve the problems of blood perfusion device without heat exchange function, unable to perform long-term extracorporeal circulation, prone to coagulation, bleeding, etc., and to reduce transmembrane pulmonary pressure difference. , Improve biocompatibility and reduce heat loss

Pending Publication Date: 2022-06-28
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. Ordinary membrane oxygenators and hemoperfusion devices are multi-piece devices. During the operation, the operator needs to open the package many times, install brackets for support, and need to connect multiple devices with pipelines. The whole process is connected There are many links and complicated operations, which affect the operation efficiency;
[0006] 2. The hemoperfusion device does not have a heat exchange function. Even if it is used together with a membrane oxygenator, it will inevitably lose a lot of heat during the operation of the pipeline, which will affect the surgical effect;
[0007] 3. Common membrane oxygenators and hemoperfusion devices are not coated with anticoagulant materials. During the operation of ECMO, a large dose of heparin is required for anticoagulation, which is prone to various complications such as coagulation and bleeding. prolonged extracorporeal circulation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Hollow fiber membrane oxygenator
  • Hollow fiber membrane oxygenator
  • Hollow fiber membrane oxygenator

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Below in conjunction with the accompanying drawings and specific embodiments, the overall scheme of the present invention is described in further detail:

[0034] see figure 1 , 2 , The structure of the specific embodiment of the present invention includes a blood perfusion system, a temperature change system and an oxygenation system, and the three systems are arranged in a coaxial concentric circle in sequence. The blood perfusion system includes the perfusion outlet switch 6, the perfusion conduit 7, the perfusion chamber shell 8 and the neutral resin particles 13; the variable temperature system includes the heat exchange chamber 4, the variable greenhouse shell 9 and the first blocking layer 16; the oxygen The oxygenation system includes an oxygenation chamber 3, an oxygenation chamber shell 18, an upper cover 14, a lower cover 15 and a second blocking layer 17; the perfusion blood pipe 7 communicates with the perfusion chamber shell 8, and neutral resin particles...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a hollow fiber membrane type oxygenator. The device comprises a blood perfusion system, a temperature changing system and an oxygenation system, the blood perfusion system comprises a perfusion device bleeding pipeline, a perfusion device chamber shell and neutral resin particles, the perfusion device bleeding pipeline is communicated with the perfusion device chamber shell, the perfusion device chamber shell is filled with the neutral resin particles, a vein blood inlet is formed in one side of the perfusion device chamber shell, and a vein blood outlet is formed in the other side of the perfusion device chamber shell. The temperature changing system comprises a heat exchange chamber and a temperature changing chamber shell, the heat exchange chamber is arranged on the outer side of the perfusion device chamber shell in a surrounding mode, the temperature changing chamber shell is arranged on the outer side of the heat exchange chamber in a surrounding mode, the oxygenation system comprises an oxygenation chamber and an oxygenation chamber shell, the oxygenation chamber is arranged on the outer side of the temperature changing chamber shell in a surrounding mode, and the oxygenation chamber shell is arranged on the outer side of the oxygenation chamber. The oxygenation chamber shell is provided with a water inlet, a water outlet, an exhaust port, an oxygenation blood outlet and an air inlet. The hemoperfusion device and the oxygenator are designed into an integrated device, so that the device is safer and more convenient to install and use, has a long-acting anticoagulation function, and meets the use of long-time ECMOs (extracorporeal circulation).

Description

technical field [0001] The invention relates to the field of medical devices, in particular to the development of a hollow fiber membrane oxygenator with blood perfusion and long-acting anticoagulation functions. Background technique [0002] ECMO is an important means of critical care and life support. Oxygenator, also known as artificial lung, is the core component of extracorporeal circulation (CPB) and extracorporeal membrane oxygenation (ECMO). The removal of carbon dioxide changes venous blood into arterial blood. At present, the hollow fiber membrane oxygenator in clinical application mainly has two functions of oxygenation and heat exchange. [0003] Patients using ECMO often express high levels of inflammatory factors in the body due to severe disease and sepsis, and a large number of inflammatory factors will continue to be produced during the operation of ECMO, which is closely related to the prognosis of patients. The hemoperfusion device contains an adsorbent...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/18A61M1/36
CPCA61M1/16A61M1/36
Inventor 闫炀郑幸龙王京玉
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products